Functions of Karez to Xinjiang Agriculture in the Qing Dynasty from the Perspective of Historical Documents

Desertification is increasingly serious in Xinjiang,and the construction of water conservancy is a precondition for the development of agriculture.The main project for the development of agriculture and water conservancy in Xinjiang is to build Karez,which played a vital role in the development of Xinjiang agriculture in the Qing Dynasty.It has been recorded many times in historical documents of the Qing Dynasty,such as Lin Zexu s Diary,Tao Baolian s Diary,Xinjiang Atlas and Zuo Zongtang s Memorial to the Emperor,etc.,which recorded the situation and historical origin of Karez.Karez made a significant contribution to the development of agriculture in the Qing Dynasty.It increased the cultivated land in Xinjiang at that time,and increased the types and yields of crops.It is conducive to the stability and development of Xinjiang s economy.Until today,Karez is still an important water source for agricultural irrigation in Xinjiang.

Agricultural Changes in Xinjiang in the Sixth Year of Guangxu s Reign from the Perspective of the Monument for Building Qarqi Canal

The Monument for Building Qarqi Canal was inscribed in the sixth year of Guangxu s reign in the Qing Dynasty(1880).This inscription made a detailed record of the event when the Qing army expelled the invading army of Mohammad Yaqub Beg,whenever the Qing army regained a place,it immediately started recruiting exiled people,restoring agriculture,building water conservancy and did other rehabilitation works.The army of the Qing Dynasty successively established rehabilitation bureaus in various parts of southern Xinjiang to be responsible for the rehabilitation works.These once again set off a climax in the development of water conservancy in multi-ethnic areas in Xinjiang,and laid the foundation for the rapid development of agricultural development and water conservancy in Xinjiang during the Guangxu s reign in the Qing Dynasty.

CCAAT/enhancer binding proteins play a role in oriLyt-dependent genome replication during MHV-68 de novo infection

Murine gammaherpesvirus 68(MHV-68),a member of the gammaherpesvirus family,replicates robustly in permissive cell lines and is able to infect laboratory mice.MHV-68 has emerged as a model for studying the basic aspects of viral replication and host–virus interactions of its human counterparts.Herpesvirus genome replication is mediated through a cis-element in the viral genome called the origin of lytic replication(oriLyt).A family of transcription factors,CCAAT/enhancer binding proteins(C/EBPs),assists in oriLyt-mediated DNA replication during gammaherpesvirus reactivation.In this study,we examined the role of C/EBPs in gammaherpesvirus DNA replication during de novo infection,using MHV-68 as a model.We found that C/EBP α and β bind to the CCAAT boxes in the MHV-68 oriLyt core region both in vitro and in vivo,as demonstrated by electrophoretic mobility shift assay and chromatin immunoprecipitation assay.A dominant negative form of C/EBPs significantly impaired the lytic replication efficiency of MHV-68 on both the plasmid and genome levels in a replication assay,indicating that functional C/EBPs are required for maximal MHV-68 genome DNA replication.Collectively,our data demonstrate that C/EBPs interact with the oriLyt core region and play an important role in MHV-68 lytic DNA replication during de novo infection.