Effect of Individualized Exercise Therapy on Cancer-related Fatigue and Negative Emotion in Patients with Gastrointestinal Tumor during Perioperative Period

[Objectives]To investigate the effect of exercise therapy in gastric cancer patients during perioperative period.[Methods]100 patients with gastric cancer who underwent elective operation in the Department of Gastrointestinal Surgery of Taihe Hospital Affiliated to Hubei University of Medicine were divided into observation group and control group by convenience sampling.The control group received routine nursing measures,and the experimental group received exercise therapy intervention measures on the basis of the control group.The patients were evaluated by the General Information Questionnaire,Self-Rating Anxiety Scale,Self-Rating Depression Scale and Cancer-related Fatigue Scale at the time of admission,the second week and the sixth week after operation.[Results]The time effect,intervention effect and interaction effect of anxiety score,depression score and cancer-related fatigue score were significant(all P<0.05)and the index of enhanced recovery after surgery was significant(P<0.05)in the two groups at the second and sixth week after operation.[Conclusions]Exercise therapy is beneficial to promoting the enhanced recovery after surgery in advance,reduce cancer-related fatigue,negative emotion and accelerate rehabilitation in patients with gastrointestinal tumors.

Knowledge Representation and Reasoning for Complex Time Expression in Clinical Text

Temporal information is pervasive and crucial in medical records and other clinical text,as it formulates the development process of medical conditions and is vital for clinical decision making.However,providing a holistic knowledge representation and reasoning framework for various time expressions in the clinical text is challenging.In order to capture complex temporal semantics in clinical text,we propose a novel Clinical Time Ontology(CTO)as an extension from OWL framework.More specifically,we identified eight timerelated problems in clinical text and created 11 core temporal classes to conceptualize the fuzzy time,cyclic time,irregular time,negations and other complex aspects of clinical time.Then,we extended Allen’s and TEO’s temporal relations and defined the relation concept description between complex and simple time.Simultaneously,we provided a formulaic and graphical presentation of complex time and complex time relationships.We carried out empirical study on the expressiveness and usability of CTO using real-world healthcare datasets.Finally,experiment results demonstrate that CTO could faithfully represent and reason over 93%of the temporal expressions,and it can cover a wider range of time-related classes in clinical domain.