Background Gastropoda,the largest class within the phylum Mollusca,houses diverse gut microbiota,and some gastropods serve as intermediate hosts for parasites.Studies have revealed that gut bacteria in gastropods are ...Background Gastropoda,the largest class within the phylum Mollusca,houses diverse gut microbiota,and some gastropods serve as intermediate hosts for parasites.Studies have revealed that gut bacteria in gastropods are associated with various biological aspects,such as growth,immunity and host-parasite interactions.Here,we summarize our current knowledge of gastropod gut microbiomes and highlight future research priorities and perspectives.Methods A literature search was undertaken using PubMed,Web of Science and CNKI for the articles on the gut microbiota of gastropods until December 31,2022.We retrieved a total of 166 articles and identified 73 eligible articles for inclusion in this review based on the inclusion and exclusion criteria.Results Our analysis encompassed freshwater,seawater and land snails,with a specific focus on parasite-transmitting gastropods.We found that most studies on gastropod gut microbiota have primarily utilized 16S rRNA gene sequencing to analyze microbial composition,rather than employing metagenomic,metatranscriptomic,or metabolomic approaches.This comprehensive review provided an overview of the parasites carried by snail species in the context of gut microbiota studies.We presented the gut microbial trends,a comprehensive summary of the diversity and composition,influencing factors,and potential functions of gastropod gut microbiota.Additionally,we discussed the potential applications,research gaps and future perspectives of gut microbiomes in parasite-transmitting gastropods.Furthermore,several strategies for enhancing our comprehension of gut microbiomes in snails were also discussed.Conclusions This review comprehensively summarizes the current knowledge on the composition,potential function,influencing factors,potential applications,limitations,and challenges of gut microbiomes in gastropods,with a specific emphasis on parasite-transmitting gastropods.These findings provide important insights for future studies aiming to understand the potential role of gastropod gut microbiota in controlling snail populations and snail-borne diseases.展开更多
基金supported by the National Key R&D Program of China(Nos.2020YFC1200100,2020YFC1200103,2021YFC2300800 and 2016YFC1200500)the National Natural Science Foundation of China(Nos.82202560,82161160343 and 82272361)+5 种基金the R&D Program in Key Areas of Guangdong Province(No.2022B1111030002)the Fundamental Research Funds for the Central University(No.22qntd4813)the Science and Technology Planning Project of Guangdong Province(No.2021B1212040017)the 111 Project(No.B12003)the 6th Nuclear Energy R&D Project(No.20201192)the National Parasitic Resource Center and Ministry of Science and Technology(No.NPRC-2019-194-30).
文摘Background Gastropoda,the largest class within the phylum Mollusca,houses diverse gut microbiota,and some gastropods serve as intermediate hosts for parasites.Studies have revealed that gut bacteria in gastropods are associated with various biological aspects,such as growth,immunity and host-parasite interactions.Here,we summarize our current knowledge of gastropod gut microbiomes and highlight future research priorities and perspectives.Methods A literature search was undertaken using PubMed,Web of Science and CNKI for the articles on the gut microbiota of gastropods until December 31,2022.We retrieved a total of 166 articles and identified 73 eligible articles for inclusion in this review based on the inclusion and exclusion criteria.Results Our analysis encompassed freshwater,seawater and land snails,with a specific focus on parasite-transmitting gastropods.We found that most studies on gastropod gut microbiota have primarily utilized 16S rRNA gene sequencing to analyze microbial composition,rather than employing metagenomic,metatranscriptomic,or metabolomic approaches.This comprehensive review provided an overview of the parasites carried by snail species in the context of gut microbiota studies.We presented the gut microbial trends,a comprehensive summary of the diversity and composition,influencing factors,and potential functions of gastropod gut microbiota.Additionally,we discussed the potential applications,research gaps and future perspectives of gut microbiomes in parasite-transmitting gastropods.Furthermore,several strategies for enhancing our comprehension of gut microbiomes in snails were also discussed.Conclusions This review comprehensively summarizes the current knowledge on the composition,potential function,influencing factors,potential applications,limitations,and challenges of gut microbiomes in gastropods,with a specific emphasis on parasite-transmitting gastropods.These findings provide important insights for future studies aiming to understand the potential role of gastropod gut microbiota in controlling snail populations and snail-borne diseases.
