Effect of Jianshen Lishui Decoction on C-reactive protein and procalcitonin in patients with acute cerebral hemorrhage

Objective:To investigate the effect of Jianshen Lishui decoction on C-reactive protein and Procalcitonin in patients with acute Cerebral Hemorrhage.Methods:120 patients with acute spontaneous Cerebral Hemorrhage were randomly divided into two groups:Control Group and the Observation Group.The Control Group was treated with routine Western medicine.The Observation Group was treated with Jianshen Lishui decoction on the basis of the Control Group.The observation period was 4 weeks,the changes of nerve function,C-reactive protein and Procalcitonin were observed before treatment and 3d,7d,14d and 4w after treatment.Results:After treatment,the scores of neurologic impairment,C-reactive protein and Procalcitonin decreased gradually with the time of treatment(3d-4w),and the scores of neurologic impairment,C-reactive protein and Procalcitonin decreased gradually,there was no difference in the score of nerve function,C-reactive protein and Procalcitonin between the two groups(P>0.05),the score of nerve function,C-reactive protein and Procalcitonin in the Observation Group were lower than those in the Control Group(P<0.05).Conclusion:Jianshen Lishui decoction can improve the neurological function of patients with acute Cerebral Hemorrhage,reduce the expression of C-reactive protein,Procalcitonin.

Effect of Buyang Huanwu Decoction on the proliferation,migration and adhesion of endothelial progenitor cells in rats with acute myocardial infarction

Objective:To investigate the intervention effect of Buyang Huanwu Decoction on endothelial progenitor cell function(EPCs),and to explore the therapeutic mechanism of Buyang Huanwu Decoction.Methods:This research take 54 rats were divided into blank group,the control group,model group,Chinese medicine,western medicine group and combine traditional Chinese and western medicine group,tonifying Yang also five decoction and atorvastatin calcium for acute myocardial infarction(AMI)rats group intervention,by using the method of density gradient centrifugation separation training each rat endothelial progenitor cells,using tetramethyl azo salt trace enzyme reaction colorimetry,used in the determination of adhesion ability and improved Boyden chamber,the method of analysis and comparison between groups of endothelial progenitor cells proliferation,adhesion and migration.Results:In 7 days,14 days and 4 weeks,acute myocardial infarction model of rat peripheral blood EPCs count,proliferation,migration and adhesion ability were compared with control group were significantly decline,tonifying Yang also five decoction group,western medicine control group and combine traditional Chinese and western medicine group of peripheral blood EPCs count,proliferation,migration and adhesion ability compared with model group were significantly increased(P<0.05),and combine traditional Chinese and western medicine group is the traditional Chinese medicine and western medicine group on the improvement of the function of EPCs effect more significantly(P<0.05).Conclusion:Statins combined with Buyang Huanwu Decoction can better improve the endothelial function of AMI rats than traditional Chinese medicine or western medicine.Further clinical studies on statins may better improve the endothelial function of AMI patients,and provide a new research entry point for improving the long-term prognosis of AMI patients.

A High-order Internal Model Based Iterative Learning Control Scheme for Discrete Linear Time-varying Systems

In this paper, an iterative learning control algorithm is proposed for discrete linear time-varying systems to track iterationvarying desired trajectories. A high-order internal model(HOIM) is utilized to describe the variation of desired trajectories in the iteration domain. In the sequel, the HOIM is incorporated into the design of learning gains. The learning convergence in the iteration axis can be guaranteed with rigorous proof. The simulation results with permanent magnet linear motors(PMLM) demonstrate that the proposed HOIM based approach yields good performance and achieves perfect tracking.

Development of a colloidal gold-based immunochromatographic strip for rapid detection of Rice stripe virus

Rice stripe virus(RSV) causes dramatic losses in rice production worldwide. In this study, two monoclonal antibodies(MAbs) 16E6 and 11 C1 against RSV and a colloidal gold-based immunochromatographic strip were developed for specific, sensitive, and rapid detection of RSV in rice plant and planthopper samples. The MAb 16E6 was conjugated with colloidal gold and the MAb 11C1 was coated on the test line of the nitrocellulose membrane of the test strip. The specificity of the test strip was confirmed by a positive reaction to RSV-infected rice plants and small brown planthopper(SBPH), and negative reactions to five other rice viruses, healthy rice plants, four other vectors of five rice viruses, and non-viruliferous SBPH. Sensitivity analyses showed that the test strip could detect the virus in RSV-infected rice plant tissue crude extracts diluted to 1:20 480(w/v, g/mL), and in individual viruliferous SBPH homogenate diluted to 1:2560(individual SPBH/μL). The validity of the developed strip was further confirmed by tests using field-collected rice and SBPH samples. This newly developed test strip is a low-cost, fast, and easy-to-use tool for on-site detection of RSV infection during field epidemiological studies and paddy field surveys, and thus can benefit decision-making for RSV management in the field.