The prevalence of kidney stone disease is increasing,afflicting 7%-11% of the United States population.Multiple systemic conditions,including obesity and diabetes,are also on the rise.Further,the literature has demons...The prevalence of kidney stone disease is increasing,afflicting 7%-11% of the United States population.Multiple systemic conditions,including obesity and diabetes,are also on the rise.Further,the literature has demonstrated a strong association between metabolic syndrome,its components,and kidney stone disease.In this article,we aim to review the associations of metabolic syndrome and nephrolithiasis,discussing the pathophysiology,urinary parameters,and clinical presentations.With this knowledge,urologists will have a more comprehensive understanding of this complex population of metabolic stone formers enabling improved patient management and treatment of stone disease.展开更多
文摘The prevalence of kidney stone disease is increasing,afflicting 7%-11% of the United States population.Multiple systemic conditions,including obesity and diabetes,are also on the rise.Further,the literature has demonstrated a strong association between metabolic syndrome,its components,and kidney stone disease.In this article,we aim to review the associations of metabolic syndrome and nephrolithiasis,discussing the pathophysiology,urinary parameters,and clinical presentations.With this knowledge,urologists will have a more comprehensive understanding of this complex population of metabolic stone formers enabling improved patient management and treatment of stone disease.