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基于TCGA数据库分析B3GAT3基因在肝癌中的表达及临床意义 被引量:1
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作者 陈哲垚 侯德富 +3 位作者 彭莉蓉 刘琼 于爱清 王启广 《湖南师范大学学报(医学版)》 2022年第6期70-75,共6页
目的:基于TCGA数据库等公共数据库中的癌症数据,分析B3GAT3基因在原发性肝癌中的表达及其临床意义.方法:基于TCGA数据库等公共数据库中的原发性肝癌患者的基因表达相关数据和相应的临床资料,采用GEPIA、UALCAN数据库工具分析B3GAT3 mRN... 目的:基于TCGA数据库等公共数据库中的癌症数据,分析B3GAT3基因在原发性肝癌中的表达及其临床意义.方法:基于TCGA数据库等公共数据库中的原发性肝癌患者的基因表达相关数据和相应的临床资料,采用GEPIA、UALCAN数据库工具分析B3GAT3 mRNA、蛋白在肝癌与正常组织之间的表达情况,比较B3GAT3基因在肝癌各临床病理分期之间的表达差异,然后进行Kaplan-Meier生存分析评估其对肝癌患者生存期的影响,最后用SPSS24.0软件做ROC曲线分析该基因作为肝癌的一个诊断指标的可行性.结果:B3GAT3 mRNA、蛋白在肝癌组织中表达比正常组织高;B3GAT3表达与肝癌的临床分期没有显著的相关性(P>0.05);B3GAT3高表达组的肝癌患者的总体生存率(OS)(P=2.4e-7<0.05)和无病生存率(DFS)(P=0.0066<0.05)低于B3GAT3低表达组的患者;B3GAT3 mRNA的表达水平是影响原发性肝癌患者OS(HR=2.5,P=6e-7<0.05)和DFS(HR=1.5,P=0.0067)的一个危险因素.B3GAT3基因作为诊断原发性肝癌的诊断指标具有一定的价值(AUC=0.740).结论:B3GAT3基因在原发性肝癌中的表达升高,但该基因在肝癌不同临床病理分期中的表达没有显著差异.B3GAT3基因高表达与肝癌患者的预后不良相关,B3GAT3基因对于肝癌患者预后是一个危险因素.该基因对肝癌的诊断有一定的意义. 展开更多
关键词 原发性肝癌 TCGA数据库 B3GAT3基因
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Relativistic viscous hydrodynamics with angular momentum 被引量:1
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作者 Duan She Anping Huang +1 位作者 defu hou Jinfeng Liao 《Science Bulletin》 SCIE EI CAS CSCD 2022年第22期2265-2268,共4页
Hydrodynamics is a general theoretical framework for describing the long-time large-distance behaviors of macroscopic physical systems.It has many important applications in various branches of physics,from cosmic expa... Hydrodynamics is a general theoretical framework for describing the long-time large-distance behaviors of macroscopic physical systems.It has many important applications in various branches of physics,from cosmic expansion and galaxy/star evolutions at the very large scales to relativistic nuclear collisions at the very small scales.The core of hydrodynamics is about physical quantities protected by exact conservation laws,such as energy,momentum and conserved charges.Past hydrodynamic studies almost entirely focus on the energy–momentum conservation and charge conservation.Only very recently,there has been a rapidly increasing interest in understanding the role of angular momentum conservation in the hydrodynamic context and its implications for spin transport of underlying constituents. 展开更多
关键词 MOMENTUM HYDRODYNAMIC entirely
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Mesonic condensation in isospin matter under rotation 被引量:1
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作者 Hui Zhang defu hou Jin-Feng Liao 《Chinese Physics C》 SCIE CAS CSCD 2020年第11期1-6,共6页
We investigate mesonic condensation in isospin matter under rotation.Using the two-flavor NJL effective model in the presence of global rotation,we demonstrate two important effects of rotation on its phase structure:... We investigate mesonic condensation in isospin matter under rotation.Using the two-flavor NJL effective model in the presence of global rotation,we demonstrate two important effects of rotation on its phase structure:a rotational suppression of the scalar-channel condensates,in particular,the pion condensation region;and a rotational enhancement of the rho condensation region with vector-channel condensate.A new phase diagram for isospin matter under rotation is mapped out on the ω−μI plane where the three distinct phases,corresponding to the σ,π,ρ-dominated regions,respectively,are separated by a second-order line at low isospin chemical potential as well as a first-order line at high rotation and are further connected at a tri-critical point. 展开更多
关键词 phase structure rotating isospin matter mesonic condensate
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Mass spectra and decay of mesons under strong external magnetic field
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作者 Shuyun Yang Meng Jin defu hou 《Chinese Physics C》 SCIE CAS CSCD 2022年第4期70-78,共9页
We study the mass spectra and decay process of σ and π_(0) mesons under a strong external magnetic field.To achieve this goal,we deduce the thermodynamic potential in a two-flavor,hot and magnetized Nambu-Jona-Lasin... We study the mass spectra and decay process of σ and π_(0) mesons under a strong external magnetic field.To achieve this goal,we deduce the thermodynamic potential in a two-flavor,hot and magnetized Nambu-Jona-Lasinio model.We calculate the energy gap equation through the random phase approximation(RPA).Then we use the Ritus method to calculate the decay triangle diagram and self-energy in the presence of a constant magnetic field B.Our results indicate that the magnetic field has little influence on the mass of π_(0) at low temperatures.However,for quarks andσmesons,their mass clearly changes,which reflects the influence of magnetic catalysis(MC).The presence of a magnetic field accelerates the decay of the meson while the presence of a chemical potential will decrease the decay process. 展开更多
关键词 magnetic field NJL model decay constant mass spectra
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Perturbation solutions of relativistic viscous hydrodynamics for longitudinally expanding fireballs
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作者 Ze-Fang Jiang Duan She +1 位作者 C.B.Yang defu hou 《Chinese Physics C》 SCIE CAS CSCD 2020年第8期164-171,共8页
The solutions of the relativistic viscous hydrodynamics for longitudinally expanding fireballs are investig-ated with the Navier-Stokes theory and Israel-Stewart theory.The energy and the Euler conservation equations ... The solutions of the relativistic viscous hydrodynamics for longitudinally expanding fireballs are investig-ated with the Navier-Stokes theory and Israel-Stewart theory.The energy and the Euler conservation equations for the viscous fluid are derived in Rindler coordinates,by assuming that the longitudinal expansion effect is small.Under the perturbation assumption,an analytical perturbation solution for the Navier-Stokes approximation and numerical solutions for the Israel-Stewart approximation are presented.The temperature evolution with both shear viscous ef-fect and longitudinal acceleration effect in the longitudinal expanding framework are presented.The specific temper-ature profile shows symmetric Gaussian shape in the Rindler coordinates.Further,we compare the results from the Israel-Stewart approximation with the results from the Bjorken and the Navier-Stokes approximations,in the pres-ence of the longitudinal acceleration expansion effect.We found that the Israel-Stewart approximation gives a good description of the early stage evolutions than the Navier-Stokes theory. 展开更多
关键词 heavy ion collision longitudinal expanding fireball viscous hydrodynamics Rindler coordinate
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Running coupling constant at finite chemical potential and magnetic field from holography
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作者 Xun Chen Lin Zhang defu hou 《Chinese Physics C》 SCIE CAS CSCD 2022年第7期8-14,共7页
According to gauge/gravity duality,we use an Einstein-Maxwell-dilaton(EMD)model to study the running coupling constant at finite chemical potential and magnetic field.First,we calculate the effect of temperature on th... According to gauge/gravity duality,we use an Einstein-Maxwell-dilaton(EMD)model to study the running coupling constant at finite chemical potential and magnetic field.First,we calculate the effect of temperature on the running coupling constant and find the results are qualitatively consistent with lattice guage theory.Subsequently,we calculate the effect of chemical potential and magnetic field on running coupling.It is found that the chemical potential and magnetic field both suppress the running coupling constant.However,the effect of the magnetic field is slightly larger than that of chemical potential for a fixed temperature.Compared with the confinement phase,the magnetic field has a large influence on the running coupling in the deconfinement phase. 展开更多
关键词 holographic QCD magnetic field running coupling
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Comparing potential-driven DBI-inspired non-minimal kinetic coupling(Dinkic) inflation with observational data
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作者 Jun Chen Wenjie hou +1 位作者 Taotao Qiu defu hou 《Chinese Physics C》 SCIE CAS CSCD 2018年第4期198-207,共10页
In our previous work [1], a new kind of inflation model was proposed, which has the interesting property that its perturbation equation of motion gets a correction of k4, due to the non-linearity of the kinetic term.N... In our previous work [1], a new kind of inflation model was proposed, which has the interesting property that its perturbation equation of motion gets a correction of k4, due to the non-linearity of the kinetic term.Nonetheless, the scale-invariance of the power spectrum remains valid, both in large-k and small-k limits. In this paper, we investigate in detail the spectral index, the index running and the tensor/scalar ratio in this model, especially in the potential-driven case, and compare the results with the current PLANCK/BICEP observational data.We also discuss the tensor spectrum in this case, which is expected to be tested by future observations of primordial gravitational waves. 展开更多
关键词 INFLATION power spectrum gravitaional waves
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