Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9...Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017).展开更多
The announcement of the Nobel Prize in Physiology or Medicine 2017 gave us a mixture of excitement and surprise.Although researchers in circadian rhythm community have been expecting this from the committee of Nobel P...The announcement of the Nobel Prize in Physiology or Medicine 2017 gave us a mixture of excitement and surprise.Although researchers in circadian rhythm community have been expecting this from the committee of Nobel Prize for quite a few years, several people had guessed that the Nobel Prize in Medicine this year would go to some scientists who discovered immune checkpoints or to those who developed gene editing tools. The Nobel Prize laureate is generally considered as a positive hero in modern science.展开更多
基金The authors declare no Competing Financial or Non-Financial Interests.This work was supported by National Center for International Research(2017B01012)National Natural Science Foundation of China(Grant Nos.31771299,81600380 and 31600958)Natural Science Foundation of Jiangsu Proving(BK20160313,BK20160317).
文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017).
基金supported by the National Natural Science Foundation of China (31771299 to Dejing Pan)
文摘The announcement of the Nobel Prize in Physiology or Medicine 2017 gave us a mixture of excitement and surprise.Although researchers in circadian rhythm community have been expecting this from the committee of Nobel Prize for quite a few years, several people had guessed that the Nobel Prize in Medicine this year would go to some scientists who discovered immune checkpoints or to those who developed gene editing tools. The Nobel Prize laureate is generally considered as a positive hero in modern science.
