Background.MALT(Mucosal Associated Lymphoid Tissue)lymphomas of the conjunctiva belong to the extranodal marginal zone B-cell lymphomas.This site,while standard,is uncommon.Case-report.A pink papular tumor developed o...Background.MALT(Mucosal Associated Lymphoid Tissue)lymphomas of the conjunctiva belong to the extranodal marginal zone B-cell lymphomas.This site,while standard,is uncommon.Case-report.A pink papular tumor developed on the lower eyelid of a 59-year-old woman.Sarcoidosis was diagnosed 9 years earlier associated with mediastinal lymphadenopathy and erythema nodosum not requiring treatment.Histological examination yielded a diagnosis of conjunctival MALT lymphoma.No visceral involvement was demonstrated.Radiotherapy(30 Gy)induced a complete response.A remote lesion developed on the patient’s arm 18 months later.No other sites were found.Further radiotherapy(26 Gy)again induced complete remission.No new lesions were seen after 24 months of follow-up.Discussion.This case is interesting because of the association of a MALT lymphoma and previous sarcoidosis,described in the literature as “sarcoidosis-lymphoma syndrome”.Association of sarcoidosis with MALT lymphomais infrequent.Treatment of conjunctival MALT lymphoma is standardized.Radiotherapy offers excellent efficacy and is well tolerated at this site.Regular and long-term follow-up is required.Local and distant relapse can occur.展开更多
文摘Background.MALT(Mucosal Associated Lymphoid Tissue)lymphomas of the conjunctiva belong to the extranodal marginal zone B-cell lymphomas.This site,while standard,is uncommon.Case-report.A pink papular tumor developed on the lower eyelid of a 59-year-old woman.Sarcoidosis was diagnosed 9 years earlier associated with mediastinal lymphadenopathy and erythema nodosum not requiring treatment.Histological examination yielded a diagnosis of conjunctival MALT lymphoma.No visceral involvement was demonstrated.Radiotherapy(30 Gy)induced a complete response.A remote lesion developed on the patient’s arm 18 months later.No other sites were found.Further radiotherapy(26 Gy)again induced complete remission.No new lesions were seen after 24 months of follow-up.Discussion.This case is interesting because of the association of a MALT lymphoma and previous sarcoidosis,described in the literature as “sarcoidosis-lymphoma syndrome”.Association of sarcoidosis with MALT lymphomais infrequent.Treatment of conjunctival MALT lymphoma is standardized.Radiotherapy offers excellent efficacy and is well tolerated at this site.Regular and long-term follow-up is required.Local and distant relapse can occur.
