Objective:To investigate the effect of compound laser acupuncture-moxibustion on blood glucose,fasting insulin and blood lipids levels in type 2 diabetes mellitus(T2DM)rats.Methods:Forty male Wistar rats were ran doml...Objective:To investigate the effect of compound laser acupuncture-moxibustion on blood glucose,fasting insulin and blood lipids levels in type 2 diabetes mellitus(T2DM)rats.Methods:Forty male Wistar rats were ran domly divided into 4 groups,in eluding the no rmal group,model control group,laser group and sham laser group(n=10 per group).The rats in the normal group were fed with a standard diet.Rats in other groups were fed with a high-sugar and high-fat diet for 4 weeks,then intraperitoneally injected with 1%streptozotocin to induce T2DM model.The laser group was irradiated by 10.6 μm and 650 nm compound laser on bilateral Pishu(BL 20),Shenshu(BL 23)and Sanyinjiao(SP 6)for 5 min,6 times a week for 5 weeks.The sham laser group received the same treatment as the laser group,but without laser output.The model control group and normal group were not treated.Blood glucose levels were measured before and after 1,2,3,4 and 5 weeks of treatment.The serum levels of fasting insulin,total cholesterol(TC),triglyceride(TG),low-density lipoprotein(LDL),and high-density lipoprotein(HDL)were analyzed after the last treatment.Results:The blood glucose levels in the model control group in creased duri ng the 5 weeks of treatment compared with the no rmal group(P<0.05),while those in the laser group were significantly lower than the model control group after weekly treatment(P<0.01 or P<0.05).After 1,2 and 3 weeks of treatment,the blood glucose levels in the laser group decreased obviously compared with the sham laser group(P<0.01 or P<0.05).Compared with the normal group,the levels of fasti ng in suli n,TC and LDL in the model control group notably in creased(P<0.01 or P<0.05),while their levels in the laser group were significantly lower than the model control group after 5 weeks of treatment(P<0.05 or P<0.01).However,no statistically significant differences were observed in TG or HDL levels among the 4 groups(P>0.05).Conclusion:The compound laser acupuncture-moxibustion of 10.6μm and 650 nm had positive effects on the regulati on of hyperglycemia and insulin resista nee in T2DM rats,which may be a potential treatment for T2DM,and also provide an alternative to the traditional acupuncture and moxibustion therapy.展开更多
Objective:To observe the clinical efficacy of herbal cake-partitioned moxibustion for dysmenorrhea due to deficiency cold.Methods:A total of 70 patients with dysmenorrhea who met the inclusion criteria were randomized...Objective:To observe the clinical efficacy of herbal cake-partitioned moxibustion for dysmenorrhea due to deficiency cold.Methods:A total of 70 patients with dysmenorrhea who met the inclusion criteria were randomized into a mild moxibustion group and a herbal cake-partitioned moxibustion group by the random number table,with 35 cases in each group.Shenque(CV 8),Zhongji(CV 3)and bilateral Zigong(EX-CA 1)were selected for both groups.The treatment continued for 3 menstrual cycles.The visual analog scale(VAS)and COX menstrual symptom scale(CMSS)were scored in both groups before treatment,after treatment and at the end of the 3rd menstrual cycle after treatment.The clinical efficacy was evaluated at the end of the 3rd menstrual cycle after treatment.Results:After treatment,the clinical efficacy of the herbal cake-partitioned moxibustion group had the tendency to be superior to that of the mild moxibustion group,while there was no statistically significant difference in the overall efficacy between the two groups(P>0.05).The VAS and CMSS scores after treatment and at the follow-up were significantly lower than those before treatment in both groups(all P<0.05).At the follow-up,the VAS scores in both groups had no significant intra-group differences from those after treatment(both P>0.05).The CMSS scores in both groups were significantly lower than those after treatment(both P<0.05).The VAS scores at the follow-up of both groups had no statistical differences from those after treatment(both P>0.05).After treatment,the CMSS score in the herbal cake-partitioned moxibustion group was significantly lower than that in the mild moxibustion group(P<0.05).At the follow-up,there were no statistical differences in the CMSS score between the two groups(P>0.05).Conclusion:The herbal cake-partitioned moxibustion has the same therapeutic efficacy for dysmenorrhea as the mild moxibustion;the two moxibustion methods can significantly improve the concomitant symptoms of dysmenorrhea,and the herbal cake-partitioned moxibustion is little better.展开更多
基金Supported by the Science Foundation of Shanghai Municipal Commission of Science and Technology(No.19441901200)the Three-Year Development Plan Project for Traditional Chinese Medicine of Shanghai Municipal Health Commission[No.ZY(2018-2020)-CCCX-2001-05]
文摘Objective:To investigate the effect of compound laser acupuncture-moxibustion on blood glucose,fasting insulin and blood lipids levels in type 2 diabetes mellitus(T2DM)rats.Methods:Forty male Wistar rats were ran domly divided into 4 groups,in eluding the no rmal group,model control group,laser group and sham laser group(n=10 per group).The rats in the normal group were fed with a standard diet.Rats in other groups were fed with a high-sugar and high-fat diet for 4 weeks,then intraperitoneally injected with 1%streptozotocin to induce T2DM model.The laser group was irradiated by 10.6 μm and 650 nm compound laser on bilateral Pishu(BL 20),Shenshu(BL 23)and Sanyinjiao(SP 6)for 5 min,6 times a week for 5 weeks.The sham laser group received the same treatment as the laser group,but without laser output.The model control group and normal group were not treated.Blood glucose levels were measured before and after 1,2,3,4 and 5 weeks of treatment.The serum levels of fasting insulin,total cholesterol(TC),triglyceride(TG),low-density lipoprotein(LDL),and high-density lipoprotein(HDL)were analyzed after the last treatment.Results:The blood glucose levels in the model control group in creased duri ng the 5 weeks of treatment compared with the no rmal group(P<0.05),while those in the laser group were significantly lower than the model control group after weekly treatment(P<0.01 or P<0.05).After 1,2 and 3 weeks of treatment,the blood glucose levels in the laser group decreased obviously compared with the sham laser group(P<0.01 or P<0.05).Compared with the normal group,the levels of fasti ng in suli n,TC and LDL in the model control group notably in creased(P<0.01 or P<0.05),while their levels in the laser group were significantly lower than the model control group after 5 weeks of treatment(P<0.05 or P<0.01).However,no statistically significant differences were observed in TG or HDL levels among the 4 groups(P>0.05).Conclusion:The compound laser acupuncture-moxibustion of 10.6μm and 650 nm had positive effects on the regulati on of hyperglycemia and insulin resista nee in T2DM rats,which may be a potential treatment for T2DM,and also provide an alternative to the traditional acupuncture and moxibustion therapy.
文摘Objective:To observe the clinical efficacy of herbal cake-partitioned moxibustion for dysmenorrhea due to deficiency cold.Methods:A total of 70 patients with dysmenorrhea who met the inclusion criteria were randomized into a mild moxibustion group and a herbal cake-partitioned moxibustion group by the random number table,with 35 cases in each group.Shenque(CV 8),Zhongji(CV 3)and bilateral Zigong(EX-CA 1)were selected for both groups.The treatment continued for 3 menstrual cycles.The visual analog scale(VAS)and COX menstrual symptom scale(CMSS)were scored in both groups before treatment,after treatment and at the end of the 3rd menstrual cycle after treatment.The clinical efficacy was evaluated at the end of the 3rd menstrual cycle after treatment.Results:After treatment,the clinical efficacy of the herbal cake-partitioned moxibustion group had the tendency to be superior to that of the mild moxibustion group,while there was no statistically significant difference in the overall efficacy between the two groups(P>0.05).The VAS and CMSS scores after treatment and at the follow-up were significantly lower than those before treatment in both groups(all P<0.05).At the follow-up,the VAS scores in both groups had no significant intra-group differences from those after treatment(both P>0.05).The CMSS scores in both groups were significantly lower than those after treatment(both P<0.05).The VAS scores at the follow-up of both groups had no statistical differences from those after treatment(both P>0.05).After treatment,the CMSS score in the herbal cake-partitioned moxibustion group was significantly lower than that in the mild moxibustion group(P<0.05).At the follow-up,there were no statistical differences in the CMSS score between the two groups(P>0.05).Conclusion:The herbal cake-partitioned moxibustion has the same therapeutic efficacy for dysmenorrhea as the mild moxibustion;the two moxibustion methods can significantly improve the concomitant symptoms of dysmenorrhea,and the herbal cake-partitioned moxibustion is little better.
