Introduction: Metabolic and vascular emergencies constitute a risk of lethality in diabetic subjects admitted to hospital. The objective was to evaluate the factors associated with death in subjects admitted for a dia...Introduction: Metabolic and vascular emergencies constitute a risk of lethality in diabetic subjects admitted to hospital. The objective was to evaluate the factors associated with death in subjects admitted for a diabetological emergency to improve management. Materials and Methods: It was a 12-month retrospective, descriptive and analytical study at Dakar’s Marc Sankale Diabetes Center. The study concerned any type of diabetics subjects admitted for a diabetological emergency. We evaluated the profile of diabetes, the pathologies found and factors associated with death. Results: We identified 697 cases of diabetic emergencies with a prevalence of 13.8%. The sex ratio (M/F) was 0.82, the mean age was 49.6 years, and the mean duration of diabetes was 7.1 years. The metabolic profile was hypoglycemia (11.3%), ketoacidosis (34.6%), and hyperosmolar hyperglycemia syndrome (5%). The associated pathologies were vascular (51.1%), infectious (65.3%), kidney function impairment (7.6%), anaemia (13.8%). During the follow-up, 94 patients died, as an annual frequency of 13.5% among diabetological emergencies. In univariate analysis, the factors significantly associated with death were age > 60 years [OR = 4.09 (2.6 - 6.41)], hyperglycemia [OR = 2.58 (1.50 - 4.4)], hyperosmolar hyperglycemia syndrome [OR = 10.5 (5.19 - 21.5)], septic diabetic foot [OR = 3.57 (2.24 - 5.66)]. Vascular pathologies that significantly associated with death were stroke [OR = 4.06 (2.10 - 7.81)], lower limb arteriopathy [OR = 3.25 (1.84 - 5.73)], cardiovascular collapse [OR = 6.85 (2.34 - 20)]. In addition to diabetes, the deceased patients had one (18%), two (34%) and at least three (45.7%) known factors of poor prognosis. Conclusion: Emergencies in diabetology remain frequent in our practice. The comorbidity (vascular and infectious) constitutes a risk of abnormally high death rate. A particular attention must concern on old diabetics subjects with several pathologies.展开更多
In this contribution, we report on the effect of solvents with different boiling points and annealing temperature on the performance of TIPS-pentacene transistors. Several solvents have been used for TIPS-pentacene th...In this contribution, we report on the effect of solvents with different boiling points and annealing temperature on the performance of TIPS-pentacene transistors. Several solvents have been used for TIPS-pentacene thin film processing: toluene, chlorobenzene and tetrahy-drofuran. To study the influence of solvent and temperature;the electrical parameters of TIPS-pentacene field effect transistor were measured. The highest values of mobilities were 7.1 × 10-3 cm2·V-1·s-1, 4.5 × 10-3?cm2·V-1·s-1 and 1.43 × 10-3 cm2·V-1·s-1 respectively for TIPS-pentacene field effect transistor using chlorobenzene, toluene and tetrahydrofuran and annealed respectively at 120°C, 150°C and 120°C. We have correlated these electrical performances with AFM images in order to point out the role of morphological properties. It is found that the grain size, and roughness highly affect the electrical parameters.展开更多
文摘Introduction: Metabolic and vascular emergencies constitute a risk of lethality in diabetic subjects admitted to hospital. The objective was to evaluate the factors associated with death in subjects admitted for a diabetological emergency to improve management. Materials and Methods: It was a 12-month retrospective, descriptive and analytical study at Dakar’s Marc Sankale Diabetes Center. The study concerned any type of diabetics subjects admitted for a diabetological emergency. We evaluated the profile of diabetes, the pathologies found and factors associated with death. Results: We identified 697 cases of diabetic emergencies with a prevalence of 13.8%. The sex ratio (M/F) was 0.82, the mean age was 49.6 years, and the mean duration of diabetes was 7.1 years. The metabolic profile was hypoglycemia (11.3%), ketoacidosis (34.6%), and hyperosmolar hyperglycemia syndrome (5%). The associated pathologies were vascular (51.1%), infectious (65.3%), kidney function impairment (7.6%), anaemia (13.8%). During the follow-up, 94 patients died, as an annual frequency of 13.5% among diabetological emergencies. In univariate analysis, the factors significantly associated with death were age > 60 years [OR = 4.09 (2.6 - 6.41)], hyperglycemia [OR = 2.58 (1.50 - 4.4)], hyperosmolar hyperglycemia syndrome [OR = 10.5 (5.19 - 21.5)], septic diabetic foot [OR = 3.57 (2.24 - 5.66)]. Vascular pathologies that significantly associated with death were stroke [OR = 4.06 (2.10 - 7.81)], lower limb arteriopathy [OR = 3.25 (1.84 - 5.73)], cardiovascular collapse [OR = 6.85 (2.34 - 20)]. In addition to diabetes, the deceased patients had one (18%), two (34%) and at least three (45.7%) known factors of poor prognosis. Conclusion: Emergencies in diabetology remain frequent in our practice. The comorbidity (vascular and infectious) constitutes a risk of abnormally high death rate. A particular attention must concern on old diabetics subjects with several pathologies.
文摘In this contribution, we report on the effect of solvents with different boiling points and annealing temperature on the performance of TIPS-pentacene transistors. Several solvents have been used for TIPS-pentacene thin film processing: toluene, chlorobenzene and tetrahy-drofuran. To study the influence of solvent and temperature;the electrical parameters of TIPS-pentacene field effect transistor were measured. The highest values of mobilities were 7.1 × 10-3 cm2·V-1·s-1, 4.5 × 10-3?cm2·V-1·s-1 and 1.43 × 10-3 cm2·V-1·s-1 respectively for TIPS-pentacene field effect transistor using chlorobenzene, toluene and tetrahydrofuran and annealed respectively at 120°C, 150°C and 120°C. We have correlated these electrical performances with AFM images in order to point out the role of morphological properties. It is found that the grain size, and roughness highly affect the electrical parameters.
