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Microsatellite instability,MMR gene expression and proliferation kinetics in colorectal cancer with famillial predisposition 被引量:14
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作者 Bao Ping Wu Ya Li Zhang +2 位作者 dian yuan zhou Chun Fang Gao Zhuo Sheng Lai 《World Journal of Gastroenterology》 SCIE CAS CSCD 2000年第6期902-905,共4页
INTRODUCTIONGenetic instability is a conunon property of manyhuman cancers,including those of HNPCC.A novel form of genetic instability involving somaticalterations,such as deletions and insertions insimple repeated s... INTRODUCTIONGenetic instability is a conunon property of manyhuman cancers,including those of HNPCC.A novel form of genetic instability involving somaticalterations,such as deletions and insertions insimple repeated sequences,has been found.Microsatellitcs are relatively short runs of tandemlyrepeated sequences scattered throughout 展开更多
关键词 colorectal neoplasms MICROSATELLITE instability gene expression FAMILIAL PREDISPOSITION proliferation kinetics immunohistochemistry POLYMERASE chain reaction flow CYTOMETRY
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