The new notions of H-metric spaces and generalized H-KKM mappings were introduced. Some generalized H-KKM type theorems for generalized H-K-KM mappings with finitely metrically compactly closed values and finitely met...The new notions of H-metric spaces and generalized H-KKM mappings were introduced. Some generalized H-KKM type theorems for generalized H-K-KM mappings with finitely metrically compactly closed values and finitely metrically compactly open values were established in H-metric spaces. These theorems generalize recent results of Khamsi and Yuan. As applications, some Ky Fan type matching theorems for finitely metrically compactly open covers and finitely metrically compactly closed covers, fixed point theorems and minimax inequality are obtained in H-metric spaces. These results generalize a number of known results in recent literature.展开更多
This paper presents the detailed results and analyses on the ecological footprints and bio-capacities of the individual cities and the province as a whole for the year 2001, providing a clear picture of sustainability...This paper presents the detailed results and analyses on the ecological footprints and bio-capacities of the individual cities and the province as a whole for the year 2001, providing a clear picture of sustainability for the province. Results show that the ecological footprints of most cities in Liaoning exceeded their respective bio-capacities, incurring high ecological deficits. The ecological deficit of the province as a whole was 1.31 ha/cap. Those cities with resources extraction and/or primary material-making as their major industries constitute the "ecologically black band", whose ecological deficits ranged from 2.45 to 5.23 ha/cap, the highest of all cities in the province. Fossil energy consumption was the major source of footprint amounting to 1.63 ha/cap at the provincial level, taking up 67.3% of the total. For cropland, modest ecological surpluses occurred in Jinzhou, Tieling, Huludao, and Panjin while modest ecological deficits in Dalian, Benxi, Fushun, and Dandong, resulting in an overall surplus for the province. Liaoning had a certain level of surplus in fishing ground (water area), mainly distributed in the coastal cities of Dalian, Panjin, Huludao, Yingkou, Jinzhou, and Dandong. Most cities had a small ecological deficit in pasture and all had a small ecological surplus in forest. The eco-efficiency, expressed as GDP value per hectare of footprint, exhibits high variations among the cities, with the highest (Shenyang) more than 10 times the lowest (Fuxin). Cities with manufacture, high-tech, and better developed service industries had high eco-efficiency, while those with resources extraction, primary material-making, and less developed service industries had low eco-efficiency. Based on the components and geographical distribution of ecological footprint, strategic policy implications are outlined for Liaoning’s development toward a sustainable future.展开更多
Objective: This study was designed to detect the expression of bcl-2 and p53 proteins in colorectal carcinomas and to determine their association with the patient survival and stage of the diseases. Methods: Immunohis...Objective: This study was designed to detect the expression of bcl-2 and p53 proteins in colorectal carcinomas and to determine their association with the patient survival and stage of the diseases. Methods: Immunohistochemistry method was used to detect the expression of bcl-2 and p53 proteins in 93 cases of colorectal carcinoma. The stain results were obtained by analyzing the clinic-pathological characteristics of patients. Results: Fifty-seven percent (53/93) of the colorectal carcinomas were bcl-2 protein positive. The positive rate of bcl-2 protein in lymph node involvement cases was lower (15/37) than the cases without node involvement (38/58, P<0.01). The positive rate of p53 protein was 43% (40/93) in colon-rectum carcinomas. No significant correlation was observed between p53 protein expression and clinic-pathological manifestations (P>0.05) but the survival was significantly worse (P=0.0001) in the p53 protein positive cases. Neither bcl-2 nor p53 alone was correlated with stage of the disease. When combined bcl-2/p53 status was analyzed, a group with bcl-2(+) and p53(?) had the best prognosis. This group was significantly associated with earlier Dukes’ stages (P=0.1763). In multivariate Cox regression analysis, lymph node involvement and p53 protein expression were two independent factors correlated with survival time. Conclusion: The expression of bcl-2 and p53 represent biological characteristics of colorectal carcinomas. Assessment of both bcl-2 and p53 status may be valuable in predicting the prognosis of patients.展开更多
A class of quasi-equilibrium problems and a class of constrained multiobjective games were introduced and studied in generalized convex spaces without linear structure. First, two existence theorems of solutions for q...A class of quasi-equilibrium problems and a class of constrained multiobjective games were introduced and studied in generalized convex spaces without linear structure. First, two existence theorems of solutions for quasi-equilibrium problems are proved in noncompact generalized convex spaces. Then, ar applications of the quasi-equilibrium existence theorem, several existence theorems of weighted Nash-equilibria and Pareto equilibria for the constrained multiobjective games are established in noncompact generalized convex spaces. These theorems improve, unify, and generalize the corresponding results of the multiobjective games in recent literatures.展开更多
We identified a novel gene ST13 from a subtraetive eDNA library of normal intestinal mueosa in 1993, more studies showed that ST13 was a co-chaperone of Hsp70s. Recently we detected the ST13 gene expression in tumor t...We identified a novel gene ST13 from a subtraetive eDNA library of normal intestinal mueosa in 1993, more studies showed that ST13 was a co-chaperone of Hsp70s. Recently we detected the ST13 gene expression in tumor tissue and adjacent normal tissue of the same colorectal cancer patient and investigated if the ST13 gene expression might have any prognostic value. Analysis was performed at molecular level by reverse transcription-PCR using real-time detection method. We measured two genes simultaneously, ST13 as the target gene and glyceraldehydes-3-phosphate dehydrogenase as a reference gene, in primary colorectal tumor specimens and tumor-adjacent normal mucosa specimens from 50 colorectal cancer patients. The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa (P〈0.05). But there were no significant differences in the expression of ST13 as compared depth, lymph node metastasis and disease-specific survival. with different Dukes' stage, tumor differentiation grade, invasion展开更多
The Pd-B/g-Al2O3 amorphous alloy catalyst and Pd/g-Al2O3 crystalline metal catalyst were prepared by KBH4 reduction and routine impregnation, respectively. Pd-B/g-Al2O3 and Pd/g-Al2O3 catalysts were characterized by ...The Pd-B/g-Al2O3 amorphous alloy catalyst and Pd/g-Al2O3 crystalline metal catalyst were prepared by KBH4 reduction and routine impregnation, respectively. Pd-B/g-Al2O3 and Pd/g-Al2O3 catalysts were characterized by XRD and SEM. It was found that the catalytic activity of the Pd-B/g-Al2O3 amorphous alloy catalyst was higher than that of the Pd/g-Al2O3 crystalline metal catalyst in the anthraquinone hydrogenation.展开更多
The C-L method was generalized from Liapunov-Schmidt reduction method, combined with theory of singularities, for study of non-autonomous dynamical systems to obtain the typical bifurcating response curves in the syst...The C-L method was generalized from Liapunov-Schmidt reduction method, combined with theory of singularities, for study of non-autonomous dynamical systems to obtain the typical bifurcating response curves in the system parameter spaces. This method has been used, ar an example, to analyze the engineering nonlinear dynamical problems by obtaining the bifurcation programs and response curves which are useful in developing techniques of control to subharmonic instability of large rotating machinery.展开更多
Focused on various BP algorithms with variable learning rate based on network system error gradient, a modified learning strategy for training non-linear network models is developed with both the incremental and the d...Focused on various BP algorithms with variable learning rate based on network system error gradient, a modified learning strategy for training non-linear network models is developed with both the incremental and the decremental factors of network learning rate being adjusted adaptively and dynamically. The golden section law is put forward to build a relationship between the network training parameters, and a series of data from an existing model is used to train and test the network parameters. By means of the evaluation of network performance in respect to convergent speed and predicting precision, the effectiveness of the proposed learning strategy can be illustrated.展开更多
The multisensor online measure system for high precision marking and cutting robot system is designed and the data fusion method is introduced, which combines augment state multiscale process with extend Kalman filter...The multisensor online measure system for high precision marking and cutting robot system is designed and the data fusion method is introduced, which combines augment state multiscale process with extend Kalman filter. The technology measuring the three-dimensional deforming information of profiled bars is applied. The experimental result shows that applying the multisensor data fusion technology can enhance the measure precision and the reliability of measure system.展开更多
According to the analysis on the characteristics of historic earthquakes in Jiangsu Province and South Huanghai Sea region, the historical earthquakes in the studied area are divided into two kinds of comparatively sa...According to the analysis on the characteristics of historic earthquakes in Jiangsu Province and South Huanghai Sea region, the historical earthquakes in the studied area are divided into two kinds of comparatively safe class and comparatively dangerous class. Then the statistical result of earthquake class, the characteristics of geo-graphical distribution and geological structures are studied. The study shows: a) In Jiangsu Province and South Huanghai Sea region, the majority of historical strong earthquakes belong to comparatively safe class, only 13.8% belong to comparatively dangerous class; b) Most historical earthquakes belong to comparatively safe class in the land area of Jiangsu, eastern sea area of Yangtze River mouth and northern depression of South Huanghai Sea region. However, along the coast of middle Jiangsu Province and in the sea area of South Huanghai Sea, the distribution of historical earthquake classes is complex and the earthquake series of comparatively dan-gerous class and comparatively safe class are equivalent in number; c) In the studied area, the statistical results of historical earthquake classes and the characteristics of spatial distribution accord very well with the real case of present-day earthquake series. It shows that the seismic activity in the region has the characteristic of succession, and the result from this study can be used as a reference for early postseismic judgment in the earthquake emer-gency work in Jiangsu Province.展开更多
A model was deveIoped to investigate impregnation behavior of thermoplastic resin into filament bundle based on Darcy's law. Consolidation processes of unidirectional laminate were performed to evaluate the validi...A model was deveIoped to investigate impregnation behavior of thermoplastic resin into filament bundle based on Darcy's law. Consolidation processes of unidirectional laminate were performed to evaluate the validity of the model. Friction spun core yarns were used in the experiments with polypropylene fiber sheath and glass filament core. The processing conditions, such as temperature and pressure, and filament parameters were taken into consideration. A good agreement was found between theoretical prediction and experiment data.展开更多
Objective To investigate the effects of Total Saponins of Panax notoginseng(PNS) and Liguastrazine(LIT) on the proliferation of cultured cerebral microvascular endothelial cells. Methods The inverted microscope was us...Objective To investigate the effects of Total Saponins of Panax notoginseng(PNS) and Liguastrazine(LIT) on the proliferation of cultured cerebral microvascular endothelial cells. Methods The inverted microscope was used to observe endothelial cells and immunochemical methods was also used to detect FVIII-related antigens so as to observe endothelial cells. PNS or LIT in concentrations 0.5?g·L -1, 1.0?g·L -1 and 2.0?g·L -1 were used on the cultured cerebral endothelial cells of rats for 24 hours. MTT method was adopted to determine the outcome of endothelial proliferation. Results 1. Immunochemical methods was used to detect FVIII-related antigens. The brownish yellow showed positive, and the observation of the cultured endothelial cells under inverted microscope showed that the cells appeared to be in the morphological form of cobble-stones. 2. PNS in lower concentration (0.5?g·L -1) could facilitate the proliferation of the cells, while 1?g·L -1 and 2?g·L -1 of PNS could inhibit the proliferation of the cells. 0.5?g·L -1 of LIT could facilitate the proliferation of cellswhile LIT of 1?g·L -1 and 2?g·L -1 had no significant effect. Conclusion The two kind of TCM ingredients extracted in lower concentration could facilitate the proliferation of the cells. And, at the same concentration, the inhibition of PNS on the cells is stronger than that of LIT.展开更多
In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated tha... In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated that IVM technology is not only used to treat infertile women with stubborn polycystic ovarian syn drome (PCOS)[2], to prevent patients from ovarian hyperstimulation syn drome (OHSS)[3],and to rescue the poor developed oocytes in stimu lated cycles , but also to reduce the cost and to avert the side-effects of gonadotropin sti mulation for in-vitro fertilization (IVF). Although there were lots of studies involving to the competence of the immature oocyte from mammalian or human ovar ies to become mature in vitro, the pregnancy rate from IVM is much lower than th at of IVF as reported[4]. This indicates that optimization of IVM remains a challenge. ……展开更多
The paper introduces a new type of cutting system: the Offline Program Profile Lining and Cutting Robot System (OPPLCRS). The system adopts the offline program technology without teaching. The system can measure and c...The paper introduces a new type of cutting system: the Offline Program Profile Lining and Cutting Robot System (OPPLCRS). The system adopts the offline program technology without teaching. The system can measure and compensate every profile’s deformation automatically, so it is suit to process any batch of profiles, and the order of processing different profiles can be arranged at will. The OPPLCRS, firstly appearing in China, will have wide application in profile cutting fields.展开更多
This paper puts forward a communication programming method between robot and external computer based on RPC (Remote Produce Call) communication method, which realizes robot distributed controlling network system model...This paper puts forward a communication programming method between robot and external computer based on RPC (Remote Produce Call) communication method, which realizes robot distributed controlling network system model. And a new Robot off line programming method is built based on this communication method and network model. Further more, as an example, robot auto marking and auto cutting of shipbuilding profile system is developed, which proves the ideas of author’s off line programming and development methods of robot flexible automation system. As a result, this paper presents a new method for developing robot flexible automation system.展开更多
文摘The new notions of H-metric spaces and generalized H-KKM mappings were introduced. Some generalized H-KKM type theorems for generalized H-K-KM mappings with finitely metrically compactly closed values and finitely metrically compactly open values were established in H-metric spaces. These theorems generalize recent results of Khamsi and Yuan. As applications, some Ky Fan type matching theorems for finitely metrically compactly open covers and finitely metrically compactly closed covers, fixed point theorems and minimax inequality are obtained in H-metric spaces. These results generalize a number of known results in recent literature.
基金Excellence midlife and youth teacher foundation of Ministry of Education No.1711
文摘This paper presents the detailed results and analyses on the ecological footprints and bio-capacities of the individual cities and the province as a whole for the year 2001, providing a clear picture of sustainability for the province. Results show that the ecological footprints of most cities in Liaoning exceeded their respective bio-capacities, incurring high ecological deficits. The ecological deficit of the province as a whole was 1.31 ha/cap. Those cities with resources extraction and/or primary material-making as their major industries constitute the "ecologically black band", whose ecological deficits ranged from 2.45 to 5.23 ha/cap, the highest of all cities in the province. Fossil energy consumption was the major source of footprint amounting to 1.63 ha/cap at the provincial level, taking up 67.3% of the total. For cropland, modest ecological surpluses occurred in Jinzhou, Tieling, Huludao, and Panjin while modest ecological deficits in Dalian, Benxi, Fushun, and Dandong, resulting in an overall surplus for the province. Liaoning had a certain level of surplus in fishing ground (water area), mainly distributed in the coastal cities of Dalian, Panjin, Huludao, Yingkou, Jinzhou, and Dandong. Most cities had a small ecological deficit in pasture and all had a small ecological surplus in forest. The eco-efficiency, expressed as GDP value per hectare of footprint, exhibits high variations among the cities, with the highest (Shenyang) more than 10 times the lowest (Fuxin). Cities with manufacture, high-tech, and better developed service industries had high eco-efficiency, while those with resources extraction, primary material-making, and less developed service industries had low eco-efficiency. Based on the components and geographical distribution of ecological footprint, strategic policy implications are outlined for Liaoning’s development toward a sustainable future.
文摘Objective: This study was designed to detect the expression of bcl-2 and p53 proteins in colorectal carcinomas and to determine their association with the patient survival and stage of the diseases. Methods: Immunohistochemistry method was used to detect the expression of bcl-2 and p53 proteins in 93 cases of colorectal carcinoma. The stain results were obtained by analyzing the clinic-pathological characteristics of patients. Results: Fifty-seven percent (53/93) of the colorectal carcinomas were bcl-2 protein positive. The positive rate of bcl-2 protein in lymph node involvement cases was lower (15/37) than the cases without node involvement (38/58, P<0.01). The positive rate of p53 protein was 43% (40/93) in colon-rectum carcinomas. No significant correlation was observed between p53 protein expression and clinic-pathological manifestations (P>0.05) but the survival was significantly worse (P=0.0001) in the p53 protein positive cases. Neither bcl-2 nor p53 alone was correlated with stage of the disease. When combined bcl-2/p53 status was analyzed, a group with bcl-2(+) and p53(?) had the best prognosis. This group was significantly associated with earlier Dukes’ stages (P=0.1763). In multivariate Cox regression analysis, lymph node involvement and p53 protein expression were two independent factors correlated with survival time. Conclusion: The expression of bcl-2 and p53 represent biological characteristics of colorectal carcinomas. Assessment of both bcl-2 and p53 status may be valuable in predicting the prognosis of patients.
文摘A class of quasi-equilibrium problems and a class of constrained multiobjective games were introduced and studied in generalized convex spaces without linear structure. First, two existence theorems of solutions for quasi-equilibrium problems are proved in noncompact generalized convex spaces. Then, ar applications of the quasi-equilibrium existence theorem, several existence theorems of weighted Nash-equilibria and Pareto equilibria for the constrained multiobjective games are established in noncompact generalized convex spaces. These theorems improve, unify, and generalize the corresponding results of the multiobjective games in recent literatures.
文摘We identified a novel gene ST13 from a subtraetive eDNA library of normal intestinal mueosa in 1993, more studies showed that ST13 was a co-chaperone of Hsp70s. Recently we detected the ST13 gene expression in tumor tissue and adjacent normal tissue of the same colorectal cancer patient and investigated if the ST13 gene expression might have any prognostic value. Analysis was performed at molecular level by reverse transcription-PCR using real-time detection method. We measured two genes simultaneously, ST13 as the target gene and glyceraldehydes-3-phosphate dehydrogenase as a reference gene, in primary colorectal tumor specimens and tumor-adjacent normal mucosa specimens from 50 colorectal cancer patients. The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa (P〈0.05). But there were no significant differences in the expression of ST13 as compared depth, lymph node metastasis and disease-specific survival. with different Dukes' stage, tumor differentiation grade, invasion
文摘The Pd-B/g-Al2O3 amorphous alloy catalyst and Pd/g-Al2O3 crystalline metal catalyst were prepared by KBH4 reduction and routine impregnation, respectively. Pd-B/g-Al2O3 and Pd/g-Al2O3 catalysts were characterized by XRD and SEM. It was found that the catalytic activity of the Pd-B/g-Al2O3 amorphous alloy catalyst was higher than that of the Pd/g-Al2O3 crystalline metal catalyst in the anthraquinone hydrogenation.
文摘The C-L method was generalized from Liapunov-Schmidt reduction method, combined with theory of singularities, for study of non-autonomous dynamical systems to obtain the typical bifurcating response curves in the system parameter spaces. This method has been used, ar an example, to analyze the engineering nonlinear dynamical problems by obtaining the bifurcation programs and response curves which are useful in developing techniques of control to subharmonic instability of large rotating machinery.
文摘Focused on various BP algorithms with variable learning rate based on network system error gradient, a modified learning strategy for training non-linear network models is developed with both the incremental and the decremental factors of network learning rate being adjusted adaptively and dynamically. The golden section law is put forward to build a relationship between the network training parameters, and a series of data from an existing model is used to train and test the network parameters. By means of the evaluation of network performance in respect to convergent speed and predicting precision, the effectiveness of the proposed learning strategy can be illustrated.
文摘The multisensor online measure system for high precision marking and cutting robot system is designed and the data fusion method is introduced, which combines augment state multiscale process with extend Kalman filter. The technology measuring the three-dimensional deforming information of profiled bars is applied. The experimental result shows that applying the multisensor data fusion technology can enhance the measure precision and the reliability of measure system.
文摘According to the analysis on the characteristics of historic earthquakes in Jiangsu Province and South Huanghai Sea region, the historical earthquakes in the studied area are divided into two kinds of comparatively safe class and comparatively dangerous class. Then the statistical result of earthquake class, the characteristics of geo-graphical distribution and geological structures are studied. The study shows: a) In Jiangsu Province and South Huanghai Sea region, the majority of historical strong earthquakes belong to comparatively safe class, only 13.8% belong to comparatively dangerous class; b) Most historical earthquakes belong to comparatively safe class in the land area of Jiangsu, eastern sea area of Yangtze River mouth and northern depression of South Huanghai Sea region. However, along the coast of middle Jiangsu Province and in the sea area of South Huanghai Sea, the distribution of historical earthquake classes is complex and the earthquake series of comparatively dan-gerous class and comparatively safe class are equivalent in number; c) In the studied area, the statistical results of historical earthquake classes and the characteristics of spatial distribution accord very well with the real case of present-day earthquake series. It shows that the seismic activity in the region has the characteristic of succession, and the result from this study can be used as a reference for early postseismic judgment in the earthquake emer-gency work in Jiangsu Province.
基金Funded by the Research Fund for the Doctoral Program of High Education
文摘A model was deveIoped to investigate impregnation behavior of thermoplastic resin into filament bundle based on Darcy's law. Consolidation processes of unidirectional laminate were performed to evaluate the validity of the model. Friction spun core yarns were used in the experiments with polypropylene fiber sheath and glass filament core. The processing conditions, such as temperature and pressure, and filament parameters were taken into consideration. A good agreement was found between theoretical prediction and experiment data.
文摘Objective To investigate the effects of Total Saponins of Panax notoginseng(PNS) and Liguastrazine(LIT) on the proliferation of cultured cerebral microvascular endothelial cells. Methods The inverted microscope was used to observe endothelial cells and immunochemical methods was also used to detect FVIII-related antigens so as to observe endothelial cells. PNS or LIT in concentrations 0.5?g·L -1, 1.0?g·L -1 and 2.0?g·L -1 were used on the cultured cerebral endothelial cells of rats for 24 hours. MTT method was adopted to determine the outcome of endothelial proliferation. Results 1. Immunochemical methods was used to detect FVIII-related antigens. The brownish yellow showed positive, and the observation of the cultured endothelial cells under inverted microscope showed that the cells appeared to be in the morphological form of cobble-stones. 2. PNS in lower concentration (0.5?g·L -1) could facilitate the proliferation of the cells, while 1?g·L -1 and 2?g·L -1 of PNS could inhibit the proliferation of the cells. 0.5?g·L -1 of LIT could facilitate the proliferation of cellswhile LIT of 1?g·L -1 and 2?g·L -1 had no significant effect. Conclusion The two kind of TCM ingredients extracted in lower concentration could facilitate the proliferation of the cells. And, at the same concentration, the inhibition of PNS on the cells is stronger than that of LIT.
文摘 In-vitro maturation (IVM) of human oocyte is an assisted reproductive technique , which has been used in clinic for more than 10 years since the first report by Cha 1991[1]. Many clinical trials have indicated that IVM technology is not only used to treat infertile women with stubborn polycystic ovarian syn drome (PCOS)[2], to prevent patients from ovarian hyperstimulation syn drome (OHSS)[3],and to rescue the poor developed oocytes in stimu lated cycles , but also to reduce the cost and to avert the side-effects of gonadotropin sti mulation for in-vitro fertilization (IVF). Although there were lots of studies involving to the competence of the immature oocyte from mammalian or human ovar ies to become mature in vitro, the pregnancy rate from IVM is much lower than th at of IVF as reported[4]. This indicates that optimization of IVM remains a challenge. ……
文摘The paper introduces a new type of cutting system: the Offline Program Profile Lining and Cutting Robot System (OPPLCRS). The system adopts the offline program technology without teaching. The system can measure and compensate every profile’s deformation automatically, so it is suit to process any batch of profiles, and the order of processing different profiles can be arranged at will. The OPPLCRS, firstly appearing in China, will have wide application in profile cutting fields.
文摘This paper puts forward a communication programming method between robot and external computer based on RPC (Remote Produce Call) communication method, which realizes robot distributed controlling network system model. And a new Robot off line programming method is built based on this communication method and network model. Further more, as an example, robot auto marking and auto cutting of shipbuilding profile system is developed, which proves the ideas of author’s off line programming and development methods of robot flexible automation system. As a result, this paper presents a new method for developing robot flexible automation system.