Dear Editor,Diterpenoids are important molecules that play significant roles in many biological processes. In plants, acyclic diterpene phytol is a representative side chain of chlorophyll, and tetracyclic diterpene g...Dear Editor,Diterpenoids are important molecules that play significant roles in many biological processes. In plants, acyclic diterpene phytol is a representative side chain of chlorophyll, and tetracyclic diterpene gibberellins ubiquitously serve as plant hormones regulating growth and development. Decoration of diterpene core struc-tures by oxidation and glycosylation are usually key steps to confer final bioactivity of diterpenoid compounds. In contrast to the extensively studied oxidases involved in gibberellin biosyn- thesis, diterpenoid-related glycosyltransferases have been scarcely documented, possibly due to the relative rarity of diter- pene glycosides in the plant kingdom. Only a few UDP-dependent glycosyltransferases （UGTs） have been characterized to participate in diterpene glycoside biosynthesis （Richman et al., 2005; Nagatoshi et al., 2012）.展开更多
基金This work was supported by the National Natural Science Foundation of China （grant nos. 31670099, 31700261）, the Key Basic Research Project of Shanghai Science and Technology Commission （grant no. 14JC1406900）, the Key Research Program of the Chinese Academy of Science （grant nos. XDPB0400, KFZD-SW-212, KFZD-SW-215） and the Strategic Priority Research Program ＂Molecular mechanism of Plant Growth and Development＂ of CAS. This work was also financiaTly supported by the National Key Laboratory of Plant Molecular Genetics, SIPPI. CAS.
文摘Dear Editor,Diterpenoids are important molecules that play significant roles in many biological processes. In plants, acyclic diterpene phytol is a representative side chain of chlorophyll, and tetracyclic diterpene gibberellins ubiquitously serve as plant hormones regulating growth and development. Decoration of diterpene core struc-tures by oxidation and glycosylation are usually key steps to confer final bioactivity of diterpenoid compounds. In contrast to the extensively studied oxidases involved in gibberellin biosyn- thesis, diterpenoid-related glycosyltransferases have been scarcely documented, possibly due to the relative rarity of diter- pene glycosides in the plant kingdom. Only a few UDP-dependent glycosyltransferases （UGTs） have been characterized to participate in diterpene glycoside biosynthesis （Richman et al., 2005; Nagatoshi et al., 2012）.
