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Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients 被引量:7
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作者 Jiangping He Shuijiang Cai +23 位作者 Huijian Feng Baomei Cai lihui lin Yuanbang Mai Yinqiang Fan Airu Zhu Huang Huang Junjie Shi dingxin li' Yuanjie Wei Yueping li Yingying Zhao’ Yuejun Pan He liu Xiaoneng Mo Xi He Shangtao Cao FengYu Hu Jincun Zhao Jie Wang Nanshan Zhong Xinwen Chen Xilong Deng Jiekai Chen 《Protein & Cell》 SCIE CAS CSCD 2020年第9期680-687,共8页
Dear Editor,In 2019,a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was identified as the causative agent of Coronavirus Disease 2019(COVID-19).As of 8 June 2020,the World Healt... Dear Editor,In 2019,a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was identified as the causative agent of Coronavirus Disease 2019(COVID-19).As of 8 June 2020,the World Health Organization(WHO)has reported 6,912,751 globally confirmed cases with 400,469 deaths.Although generally causes mild disease,SARS-CoV-2 infection can result in serious outcomes,including acute lung injury(ALI)and acute respiratory distress syndrome(ARDS),the leading cause of mortality in patients with comorbidities.Recent autopsy studies of COVID-19 patients revealed mononuclear infiltration and excessive production of mucus in the infected lung,especially in the damaged small airways and alveoli(Bian and Team,2020;Liu et al.,2020). 展开更多
关键词 PATIENTS ACUTE LUNG
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