Indigenous peoples are the custodians of traditional knowledge,encompassing their ideas,innovations,and methods.Throughout history,both plants and animals have served as valuable sources for medicinal remedies,capable...Indigenous peoples are the custodians of traditional knowledge,encompassing their ideas,innovations,and methods.Throughout history,both plants and animals have served as valuable sources for medicinal remedies,capable of treating or preventing illnesses.This article aims to offer a concise overview of the traditional medical uses of vertebrates and the derived products in both human and veterinary medicine.Animal species are utilized as raw materials,and the resulting products are employed to cure a wide array of ailments.In different regions of India,indigenous peoples have diverse traditional applications for vertebrates and their by-products,which are utilized to treat human and animal illnesses.In various parts of India,medical practices involve the use of forty percent mammals,seven percent birds,eleven percent reptiles,eight percent fish,and two percent amphibians.Kerala employs around 69 different animal species and their by-products for the treatment of human and veterinary ailments.Similarly,the Theni district of Tamil Nadu utilizes 69 animals,the state of Madhya Pradesh employs 18 animals,the state of Tripura utilizes 25 animals,and the state of Assam employs 44 animals for the treatment of human and veterinary illnesses.Consequently,the main objective of this review is to provide a summary of the traditional therapeutic applications of animals and the resulting products.展开更多
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region.The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi,which is transmitted by chi...Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region.The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi,which is transmitted by chigger bites or larval mite bites.Scrub typhus is a threat to billions of people worldwide causing different health complications and acute encephalitis in infants and growing children.The disease causes multiple organ failure and mortality rates may reach up to 70%due to a lack of appropriate healthcare.Currently available genome and proteome databases,and bioinformatics methods are valuable tools to develop novel therapeutics to curb the pathogen.This review discusses the state-of-the-art of information about Orientia tsutsugamushi-mediated scrub typhus and delineates the role of omics technologies to develop drugs against the pathogen.The role of proteome-wide in silico approaches for the identification of therapeutic targets is also highlighted.展开更多
文摘Indigenous peoples are the custodians of traditional knowledge,encompassing their ideas,innovations,and methods.Throughout history,both plants and animals have served as valuable sources for medicinal remedies,capable of treating or preventing illnesses.This article aims to offer a concise overview of the traditional medical uses of vertebrates and the derived products in both human and veterinary medicine.Animal species are utilized as raw materials,and the resulting products are employed to cure a wide array of ailments.In different regions of India,indigenous peoples have diverse traditional applications for vertebrates and their by-products,which are utilized to treat human and animal illnesses.In various parts of India,medical practices involve the use of forty percent mammals,seven percent birds,eleven percent reptiles,eight percent fish,and two percent amphibians.Kerala employs around 69 different animal species and their by-products for the treatment of human and veterinary ailments.Similarly,the Theni district of Tamil Nadu utilizes 69 animals,the state of Madhya Pradesh employs 18 animals,the state of Tripura utilizes 25 animals,and the state of Assam employs 44 animals for the treatment of human and veterinary illnesses.Consequently,the main objective of this review is to provide a summary of the traditional therapeutic applications of animals and the resulting products.
基金Department of Health Research,Government of India,New Delhi,India(Grant number:YSS/2020/000116/PRCYSS)。
文摘Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region.The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi,which is transmitted by chigger bites or larval mite bites.Scrub typhus is a threat to billions of people worldwide causing different health complications and acute encephalitis in infants and growing children.The disease causes multiple organ failure and mortality rates may reach up to 70%due to a lack of appropriate healthcare.Currently available genome and proteome databases,and bioinformatics methods are valuable tools to develop novel therapeutics to curb the pathogen.This review discusses the state-of-the-art of information about Orientia tsutsugamushi-mediated scrub typhus and delineates the role of omics technologies to develop drugs against the pathogen.The role of proteome-wide in silico approaches for the identification of therapeutic targets is also highlighted.
