Background: Patients who underwent percutaneous coronary intervention in left main coronary artery (LMCA) requires special concern, being high risk and increasing patient population. The aim of this study was to asses...Background: Patients who underwent percutaneous coronary intervention in left main coronary artery (LMCA) requires special concern, being high risk and increasing patient population. The aim of this study was to assess the clinical profile, angiographic status, and prevalence of restenosis in patients who underwent percutaneous transluminal coronary angioplasty (PTCA) in LMCA. Materials and Methods: This observational cohort study included 17 patients who underwent PTCA in LMCA during one-year study period at tertiary care centers in Government Medical College, Kozhikode, India. Data including various risk factors, clinical and angiographic details, stent used, procedural complications and outcomes including rate of restenosis were analyzed. Results: A total of 17 patients (mean age 53.88 ± 9.80 years) with 76.47% of males were included in the study. Smoking and hypertension were the most common risk factors presented in 52.94% and 47.06% of patients respectively. Single vessel disease (SVD) of LMCA was the most common pattern observed in 47.10%;the rate of restenosis was observed in 11.76% patients. Revascularization was performed in one patient (5.88%) with coronary artery bypass graft and in one patient (5.88%) with PTCA using drug eluting stent (DES). The overall procedural success was 88.24% in this study. Survival rate was 100% at one-year follow-up period. Conclusion: Our study involved patients who underwent PTCA in LMCA, showed smoking as a most prevalent risk factor for coronary artery disease and SVD as a most common pattern, comparatively low rate of restenosis and 100% of survival rate at one-year follow-up period.展开更多
Objective: The aim of this study was to evaluate cardiovascular involvement in patients with connective tissue diseases. Methods: A total of 99 patients (mean age 36.6 ± 10.7 years) with connective tissue disease...Objective: The aim of this study was to evaluate cardiovascular involvement in patients with connective tissue diseases. Methods: A total of 99 patients (mean age 36.6 ± 10.7 years) with connective tissue diseases were included in the study. Patients were assessed based on their sex, age, disease duration, cardiovascular symptoms, erythrocyte sedimentation rate, antinuclear antibody, and anti-double stranded DNA antibodies. Moreover, cardiac investigations including electrocardiography (ECG), chest X-ray and echocardiography were performed. Results: The study included 90 (90.9%) females and 9 (9.09%) males, aged between 18 and 64 years. Chest pain, palpitation, dyspnoea on exertion, syncope, fatigue, and cardiac murmur were the most cardiac symptoms and signs of patients. ECG abnormalities associated with sinus bradycardia, sinus tachycardia, ST interval and T waves, were found in 27% patients. Chest X-ray with cardiomegaly was found in 10 (10.1%) patients. Echocardiography abnormalities were observed in 32% of patients with pericardial involvement, mitral regurgitation, and diastolic dysfunction. Moreover, the incidence of pericardial effusion was found to be significantly (p higher in patients with connective tissue diseases. Conclusion: The study indicates the correlation between disease activity, disease duration and abnormal echocardiography of cardiovascular involvement in connective tissue diseases.展开更多
文摘Background: Patients who underwent percutaneous coronary intervention in left main coronary artery (LMCA) requires special concern, being high risk and increasing patient population. The aim of this study was to assess the clinical profile, angiographic status, and prevalence of restenosis in patients who underwent percutaneous transluminal coronary angioplasty (PTCA) in LMCA. Materials and Methods: This observational cohort study included 17 patients who underwent PTCA in LMCA during one-year study period at tertiary care centers in Government Medical College, Kozhikode, India. Data including various risk factors, clinical and angiographic details, stent used, procedural complications and outcomes including rate of restenosis were analyzed. Results: A total of 17 patients (mean age 53.88 ± 9.80 years) with 76.47% of males were included in the study. Smoking and hypertension were the most common risk factors presented in 52.94% and 47.06% of patients respectively. Single vessel disease (SVD) of LMCA was the most common pattern observed in 47.10%;the rate of restenosis was observed in 11.76% patients. Revascularization was performed in one patient (5.88%) with coronary artery bypass graft and in one patient (5.88%) with PTCA using drug eluting stent (DES). The overall procedural success was 88.24% in this study. Survival rate was 100% at one-year follow-up period. Conclusion: Our study involved patients who underwent PTCA in LMCA, showed smoking as a most prevalent risk factor for coronary artery disease and SVD as a most common pattern, comparatively low rate of restenosis and 100% of survival rate at one-year follow-up period.
文摘Objective: The aim of this study was to evaluate cardiovascular involvement in patients with connective tissue diseases. Methods: A total of 99 patients (mean age 36.6 ± 10.7 years) with connective tissue diseases were included in the study. Patients were assessed based on their sex, age, disease duration, cardiovascular symptoms, erythrocyte sedimentation rate, antinuclear antibody, and anti-double stranded DNA antibodies. Moreover, cardiac investigations including electrocardiography (ECG), chest X-ray and echocardiography were performed. Results: The study included 90 (90.9%) females and 9 (9.09%) males, aged between 18 and 64 years. Chest pain, palpitation, dyspnoea on exertion, syncope, fatigue, and cardiac murmur were the most cardiac symptoms and signs of patients. ECG abnormalities associated with sinus bradycardia, sinus tachycardia, ST interval and T waves, were found in 27% patients. Chest X-ray with cardiomegaly was found in 10 (10.1%) patients. Echocardiography abnormalities were observed in 32% of patients with pericardial involvement, mitral regurgitation, and diastolic dysfunction. Moreover, the incidence of pericardial effusion was found to be significantly (p higher in patients with connective tissue diseases. Conclusion: The study indicates the correlation between disease activity, disease duration and abnormal echocardiography of cardiovascular involvement in connective tissue diseases.
