Proteomics has evolved into a powerful and widely used bioanalytical technique in the study of cancer,especially hepatocellular carcinoma (HCC).In this review,we provide an up to date overview of feasible proteome-ana...Proteomics has evolved into a powerful and widely used bioanalytical technique in the study of cancer,especially hepatocellular carcinoma (HCC).In this review,we provide an up to date overview of feasible proteome-analytical techniques for clinical questions.In addition,we present a broad summaryof proteornic studies of HCC utilizing various technical approaches for the analysis of samples derived from diverse sources like HCC cell lines,animal models,human tissue and body fluids.展开更多
基金D.A.Megger and B.Sitek acknowledge the financial support from the PROFILE-consortium Ruhr.PROFILE is co-funded by the European Unionthe German federal state North Rhine-Westphaliaproject number z0911bt004e
文摘Proteomics has evolved into a powerful and widely used bioanalytical technique in the study of cancer,especially hepatocellular carcinoma (HCC).In this review,we provide an up to date overview of feasible proteome-analytical techniques for clinical questions.In addition,we present a broad summaryof proteornic studies of HCC utilizing various technical approaches for the analysis of samples derived from diverse sources like HCC cell lines,animal models,human tissue and body fluids.