期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
重组人生长激素对兔角膜损伤早期修复的研究 被引量:1
1
作者 张弛 赵刚平 +2 位作者 王萍 程冬梅 谢莉 《国际眼科杂志》 CAS 北大核心 2021年第6期975-979,共5页
目的:探讨重组人生长激素(rHGH)对兔角膜上皮损伤早期的修复作用。方法:选取32只健康雄性新西兰兔制作双眼角膜上皮损伤模型,随机选取1眼滴无菌生理盐水作为对照组,另1眼滴20nmol/L重组人生长激素作为rHGH组,分别于造模前、造模后24、48... 目的:探讨重组人生长激素(rHGH)对兔角膜上皮损伤早期的修复作用。方法:选取32只健康雄性新西兰兔制作双眼角膜上皮损伤模型,随机选取1眼滴无菌生理盐水作为对照组,另1眼滴20nmol/L重组人生长激素作为rHGH组,分别于造模前、造模后24、48、72h采用荧光素钠染色法观察角膜上皮愈合情况,采用Cochet-Bonnet角膜知觉测量仪测量检查中央角膜敏感度,同时收集各时间点泪液检测炎症因子的表达。结果:造模后48h对照组和rHGH组角膜上皮愈合率分别为62.52%±6.73%和79.62%±10.62%(P<0.05),造模后72h分别为90.56%±9.57%和98.43%±3.65%(P<0.05)。造模后48h,对照组和rHGH组中央角膜敏感度分别为3.22±0.42、4.22±0.26cm(P<0.05)。造模后各时间点两组泪液TNF-α和IL-1α表达均较造模前增加,且对照组均高于rHGH组。造模后24、48h,两组泪液MMP-9表达均较造模前增加,且造模后48h对照组高于rHGH组(均P<0.05)。造模后24、48h两组泪液IL-21表达均较造模前增加(P<0.05)。造模后各时间点两组泪液IL-17α、Leptin表达与造模前相比及两组之间比较均无差异(P>0.05)。结论:重组人生长激素有利于兔角膜上皮损伤早期修复。 展开更多
关键词 重组人生长激素 角膜上皮损伤 修复 炎症因子
下载PDF
The complexity of climate reconstructions using the coexistence approach on Qinghai-Tibetan Plateau 被引量:2
2
作者 Zhi-Yong Zhang dong-mei cheng +3 位作者 cheng-Sen Li Wan Hu Xuan-Huai Zhan Hong-Li Ji 《Journal of Palaeogeography》 SCIE CSCD 2019年第1期68-77,共10页
Quantifying the palaeoclimates of Qinghai–Tibetan Plateau is vital for understanding the uplift history of plateau and the evolution of Asian monsoon since Cenozoic. Recently, the Coexistence Approach(CA) has been em... Quantifying the palaeoclimates of Qinghai–Tibetan Plateau is vital for understanding the uplift history of plateau and the evolution of Asian monsoon since Cenozoic. Recently, the Coexistence Approach(CA) has been employed to reconstruct the palaeoelevation and palaeoclimate of the plateau by several studies. However, the application of CA in mountainous areas and the realism of climate reconstructions via this method are seldom discussed,although the complexity of reconstructions is speculated. Here we reevaluated the realism of climate reconstruction using the CA with modern pollen samples from the Qinghai–Tibetan Plateau, and try to explore the possible factors influencing the precipitation and temperature reconstructions by CA. We suggest that the long-distance transport pollen as a result of the Asian summer monsoon potentially significantly affects the reconstructions both for precipitation and temperature. The precipitation complexly interacting with snowmelt and permafrost thaw leads to the discrepancy between the reconstructed precipitation and the real value. The response temperature for blossoming of dwarfed plants on the plateau is mostly likely higher than the air temperature(usually measured at1.5 m above ground) due to energy flux or morphological adaptation of inflorescences during the growing season,causing the distortion of temperature reconstructions. Precipitation reconstruction is notoriously difficult as the establishers of CA have already suggested, but reconstructing the low temperatures may be even more challenging on Qinghai–Tibetan Plateau. Though all of the explorations in current paper are in a qualitative way, it offers an inspiration of how appropriately interpret the disagreements between CA results and the observations, and of how to obtain a reasonable reconstruction of palaeoclimate of the plateau. 展开更多
关键词 COMPLEXITY CLIMATE reconstruction COEXISTENCE approach Modern POLLEN ASSEMBLAGES Qinghai-Tibetan PLATEAU
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部