Depression is a recurrent,common,and potentially life-threatening psychiatric disease.Intestinal flora is a large number of microbial communities that are parasitic in the human digestive tract.Current evidence sugges...Depression is a recurrent,common,and potentially life-threatening psychiatric disease.Intestinal flora is a large number of microbial communities that are parasitic in the human digestive tract.Current evidence suggests that the occurrence of depression may be related to intestinal flora.Long time ago,Bai He Di Huang decoction was used to treat the depression.Recently,researchers found that Bai He Di Huang decoction could affect the the intestinal flora of patients with depression.This review focuses on the clinical progress of Bai He Di Huang decoction in the treatment of depression,and explores the effect and mechanism of Bai He Di Huang decoction on the intestinal flora of depressive mouse.展开更多
We present here the application of one-dimensional and two-dimensional NMR techniques to characterize the structure of methoxyl end-functionalized polystyrenes （PS）. The peaks in 1H-NMR spectra corresponding to main...We present here the application of one-dimensional and two-dimensional NMR techniques to characterize the structure of methoxyl end-functionalized polystyrenes （PS）. The peaks in 1H-NMR spectra corresponding to main-chain, side-chain and chain-end groups are assigned by 1H-1H gCOSY, 1H-13C gHSQC and gHMBC spectra. For the first time, the spin-lattice relaxation time （T1） of protons of the chain-ends is revealed to be affected more by polymer molecular weight （MW） than by the protons of the main-chains and the side-chains （almost independent from MW）. As a result, a much higher delay time （dl） for chain-ends （d1〉 20T1） is needed for quantitative NMR measurement when using end-group estimation method to obtain the MW of PS, which is in accordance with the value estimated by GPC. An improved method for the polymer MW determination is established, by combination of different NMR techniques to distinguish the peaks, and a large dl setting to achieve quantitative NMR analysis.展开更多
文摘Depression is a recurrent,common,and potentially life-threatening psychiatric disease.Intestinal flora is a large number of microbial communities that are parasitic in the human digestive tract.Current evidence suggests that the occurrence of depression may be related to intestinal flora.Long time ago,Bai He Di Huang decoction was used to treat the depression.Recently,researchers found that Bai He Di Huang decoction could affect the the intestinal flora of patients with depression.This review focuses on the clinical progress of Bai He Di Huang decoction in the treatment of depression,and explores the effect and mechanism of Bai He Di Huang decoction on the intestinal flora of depressive mouse.
基金supported by the National Natural Science Foundation of China(Nos.21274099,21305098 and 21474067)the Priority Academic Program Development of Jiangsu High Education Institutions
文摘We present here the application of one-dimensional and two-dimensional NMR techniques to characterize the structure of methoxyl end-functionalized polystyrenes （PS）. The peaks in 1H-NMR spectra corresponding to main-chain, side-chain and chain-end groups are assigned by 1H-1H gCOSY, 1H-13C gHSQC and gHMBC spectra. For the first time, the spin-lattice relaxation time （T1） of protons of the chain-ends is revealed to be affected more by polymer molecular weight （MW） than by the protons of the main-chains and the side-chains （almost independent from MW）. As a result, a much higher delay time （dl） for chain-ends （d1〉 20T1） is needed for quantitative NMR measurement when using end-group estimation method to obtain the MW of PS, which is in accordance with the value estimated by GPC. An improved method for the polymer MW determination is established, by combination of different NMR techniques to distinguish the peaks, and a large dl setting to achieve quantitative NMR analysis.
