A method for determination of alkaline phosphatase (ALP) in BALB/c mouse fetal liver stromal cells has been described based on the catalytic reaction. After the cell extract is incubated with the substrate disodium p...A method for determination of alkaline phosphatase (ALP) in BALB/c mouse fetal liver stromal cells has been described based on the catalytic reaction. After the cell extract is incubated with the substrate disodium phenyl phosphate, the reaction product phenol generated by ALP is determined by capillary electrophoresis with electrochemical detection.展开更多
The precipitation of ordered alpha_2 phase in a near - alphaTi-6.3Al-4.8Sn-2.0Zr-1.0Mo-0.34Si-0.9Nd (mass fraction) alloy with duplex microstructure, duringaging at various temperatures, was investigated. It is conclu...The precipitation of ordered alpha_2 phase in a near - alphaTi-6.3Al-4.8Sn-2.0Zr-1.0Mo-0.34Si-0.9Nd (mass fraction) alloy with duplex microstructure, duringaging at various temperatures, was investigated. It is concluded that the precipitation and growthof the alpha_2 phase can be controlled by suitable selection of the aging temperature. Aging athigher temperatures can result in the uniform precipitation and growth of alpha_2 ordered phase inalpha_p whereas the alpha_2 ordered phase precipitated only at the lamella boundaries anddislocations in beta_t. Aging at a moderate temperature can promote the tendency of uniformprecipitation of alpha_2 phase in both alpha_p and beta_t. Aging at a relatively low temperature issuitable for the uniform precipitation and growth of fine alpha_2 particles throughout both thealpha_p and beta_t matrix.展开更多
Type 1 diabetes is an autoimmune dise as e resulting from the selective destruction of β cells in the pa ncreatic islets. In both human and rodent models of type 1 diabetes, the clinica l disease is preceded by a pro...Type 1 diabetes is an autoimmune dise as e resulting from the selective destruction of β cells in the pa ncreatic islets. In both human and rodent models of type 1 diabetes, the clinica l disease is preceded by a progressive mononuclear cell invasion of the pancreat ic islets (insulitis). In the early stage of insulitis,the major components are monocyte/macrophages, and the recruitment of mononuclear cells is a critical st ep in the pathogenesis of the type 1 diabetes. Studies have revealed that Monocy te chemoattractant protein-1(MCP-1) specifically recruits monocytes/ macrophag es into pancreas and plays an important role in the development of insulitis and diabetes.展开更多
文摘A method for determination of alkaline phosphatase (ALP) in BALB/c mouse fetal liver stromal cells has been described based on the catalytic reaction. After the cell extract is incubated with the substrate disodium phenyl phosphate, the reaction product phenol generated by ALP is determined by capillary electrophoresis with electrochemical detection.
文摘The precipitation of ordered alpha_2 phase in a near - alphaTi-6.3Al-4.8Sn-2.0Zr-1.0Mo-0.34Si-0.9Nd (mass fraction) alloy with duplex microstructure, duringaging at various temperatures, was investigated. It is concluded that the precipitation and growthof the alpha_2 phase can be controlled by suitable selection of the aging temperature. Aging athigher temperatures can result in the uniform precipitation and growth of alpha_2 ordered phase inalpha_p whereas the alpha_2 ordered phase precipitated only at the lamella boundaries anddislocations in beta_t. Aging at a moderate temperature can promote the tendency of uniformprecipitation of alpha_2 phase in both alpha_p and beta_t. Aging at a relatively low temperature issuitable for the uniform precipitation and growth of fine alpha_2 particles throughout both thealpha_p and beta_t matrix.
文摘Type 1 diabetes is an autoimmune dise as e resulting from the selective destruction of β cells in the pa ncreatic islets. In both human and rodent models of type 1 diabetes, the clinica l disease is preceded by a progressive mononuclear cell invasion of the pancreat ic islets (insulitis). In the early stage of insulitis,the major components are monocyte/macrophages, and the recruitment of mononuclear cells is a critical st ep in the pathogenesis of the type 1 diabetes. Studies have revealed that Monocy te chemoattractant protein-1(MCP-1) specifically recruits monocytes/ macrophag es into pancreas and plays an important role in the development of insulitis and diabetes.