Coronavirus disease 2019(COVID-19)has spread throughout China.However,information about COVID-19 in cities and regions outside Wuhan is limited and the indicators that predict the length of hospital stay for patients ...Coronavirus disease 2019(COVID-19)has spread throughout China.However,information about COVID-19 in cities and regions outside Wuhan is limited and the indicators that predict the length of hospital stay for patients with COVID-19 are unclear.Therefore,we collected clinical data from 47 patients with COVID-19 in Quanzhou City.The median age was 38 years[interquartile range(IQR):31–50 years],and 24(51%)were male.There were 8 mild,36 moderate,and 3 severe/critical cases.The median interval from exposure to disease onset was 13 days(IQR:8–18 days).The incidence of severe/critical cases was 33%(3/10)in patients with hypertension.Common symptoms included fever(83%),cough(77%),fatigue(40%),a sore,dry throat(28%),and diarrhea(21%).One patient(2%)developed respiratory distress syndrome on day 13 of inpatient treatment.Six patients had leukopenia,17 had elevated C-reactive protein(CRP),and 8 had lymphocytopenia and elevated lactate dehydrogenase(LDH).The median length of hospitalization was 22 days(IQR:16-30 days).Dynamic monitoring of LDH,CRP,and neutrophil-lymphocyte ratio predicted whether length of hospitalization would exceed 21 days.Most patients presented with mild and moderate disease.Patients with hypertension were more likely to become severe or critical.Dynamic monitoring of LDH,CRP,and neutrophil-lymphocyte ratio levels can help predict delayed discharge from the hospital.展开更多
基金the Natural Science Foundation of China(81400625)Natural Science Foundation of Fujian Province(2019J01593,2017J01228)+2 种基金High-Level Talent Innovation Project of Quanzhou(2018C067R)Science and Technology Innovation Project of Fujian Province(2019Y9048)Pilot Project of Fujian Provincial Department of Science&Technology(2020Y0005)。
文摘Coronavirus disease 2019(COVID-19)has spread throughout China.However,information about COVID-19 in cities and regions outside Wuhan is limited and the indicators that predict the length of hospital stay for patients with COVID-19 are unclear.Therefore,we collected clinical data from 47 patients with COVID-19 in Quanzhou City.The median age was 38 years[interquartile range(IQR):31–50 years],and 24(51%)were male.There were 8 mild,36 moderate,and 3 severe/critical cases.The median interval from exposure to disease onset was 13 days(IQR:8–18 days).The incidence of severe/critical cases was 33%(3/10)in patients with hypertension.Common symptoms included fever(83%),cough(77%),fatigue(40%),a sore,dry throat(28%),and diarrhea(21%).One patient(2%)developed respiratory distress syndrome on day 13 of inpatient treatment.Six patients had leukopenia,17 had elevated C-reactive protein(CRP),and 8 had lymphocytopenia and elevated lactate dehydrogenase(LDH).The median length of hospitalization was 22 days(IQR:16-30 days).Dynamic monitoring of LDH,CRP,and neutrophil-lymphocyte ratio predicted whether length of hospitalization would exceed 21 days.Most patients presented with mild and moderate disease.Patients with hypertension were more likely to become severe or critical.Dynamic monitoring of LDH,CRP,and neutrophil-lymphocyte ratio levels can help predict delayed discharge from the hospital.
