Using Feed Forward BPNN for Forecasting All Share Price Index

Use of artificial neural networks has become a significant and an emerging research method due to its capability of capturing nonlinear behavior instead of conventional time series methods. Among them, feed forward back propagation neural network (BPNN) is the widely used network topology for forecasting stock prices indices. In this study, we attempted to find the best network topology for one step ahead forecasting of All Share Price Index (ASPI), Colombo Stock Exchange (CSE) by employing feed forward BPNN. The daily data including ASPI, All Share Total Return Index (ASTRI), Market Price Earnings Ratio (PER), and Market Price to Book Value (PBV) were collected from CSE over the period from January 2nd 2012 to March 20th 2014. The experiment is implemented by prioritizing the number of inputs, learning rate, number of hidden layer neurons, and the number of training sessions. Eight models were selected on basis of input data and the number of training sessions. Then the best model was used for forecasting next trading day ASPI value. Empirical result reveals that the proposed model can be used as an approximation method to obtain next day value. In addition, it showed that the number of inputs, number of hidden layer neurons and the training times are significant factors that can be affected to the accuracy of forecast value.

FlowDNN:a physics-informed deep neural network for fast and accurate flow prediction

For flow-related design optimization problems,e.g.,aircraft and automobile aerodynamic design,computational fluid dynamics(CFD)simulations are commonly used to predict flow fields and analyze performance.While important,CFD simulations are a resource-demanding and time-consuming iterative process.The expensive simulation overhead limits the opportunities for large design space exploration and prevents interactive design.In this paper,we propose Flow DNN,a novel deep neural network(DNN)to efficiently learn flow representations from CFD results.Flow DNN saves computational time by directly predicting the expected flow fields based on given flow conditions and geometry shapes.Flow DNN is the first DNN that incorporates the underlying physical conservation laws of fluid dynamics with a carefully designed attention mechanism for steady flow prediction.This approach not only improves the prediction accuracy,but also preserves the physical consistency of the predicted flow fields,which is essential for CFD.Various metrics are derived to evaluate Flow DNN with respect to the whole flow fields or regions of interest(RoIs)(e.g.,boundary layers where flow quantities change rapidly).Experiments show that Flow DNN significantly outperforms alternative methods with faster inference and more accurate results.It speeds up a graphics processing unit(GPU)accelerated CFD solver by more than 14000×,while keeping the prediction error under 5%.

Pharmacokinetics and bioequivalence evaluation of lenalidomide in Chinese patients with multiple myeloma

To the Editor:Multiple myeloma(MM)is currently considered to be an incurable neoplasm and a systemic disease,and the first line of treatment plays a crucial role in MM patients,since the majority of patients do not survive beyond the first-line treatment.[1]Lenalidomide,a first-line drug in the treatment of MM,is sold as a capsule under the trade name Revlimid®,which is in great demand for an increasing incidence of MM.