The low degree of development and utilization as well as the contradiction between supply and demand of water resources in Huangshui River basin are the main restricting factors of the local agricultural development. ...The low degree of development and utilization as well as the contradiction between supply and demand of water resources in Huangshui River basin are the main restricting factors of the local agricultural development. The study on the simulation of irrigation water loss based on the VSMB model has very important significance to strengthening regional water management and improving water resource utilization efficiency. Five groundwater wells were set up to carry out the farmland irrigation water infiltration and the experimental study on groundwater dynamic effect. Two soil moisture monitoring sites were set up in two typical plots of Daxia and Guanting irrigation area at the same time and TDR300 was used to monitor four kinds of deep soil moisture( 10 cm,30 cm,50 cm and 70 cm). On this basis,the VSMB model was used to study the irrigation water loss in the irrigation area of Yellow River valley of Qinghai Province,including soil moisture content,the actual evapotranspiration,infiltration,runoff,groundwater buried depth and so on. The results showed that the water consumption caused by soil evaporation and crop transpiration accounted for 46. 4% and 24. 1% of the total precipitation plus irrigation,respectively,and the leakage accounted for 30. 3% and 60. 6% of the total precipitation plus irrigation,respectively,from March 1,2013 to April 30,and from August 1 to September 30. The actual evaporation of the GT- TR1 and GT- TR2 sites in the whole year of 2013 was 632. 6 mm and 646. 9 mm,respectively,and the leakage accounted for 2. 6% and 1. 2% of the total precipitation plus irrigation,respectively. RMSE of the simulation results of the groundwater depth in Daxia irrigation area during the two periods was 92. 3 mm and 27. 7 mm,respectively. And RMSE of the simulation results of the water content of soil profile in the two monitoring sites of Guanting irrigation area was 2. 04% and 5. 81%,respectively,indicating that the simulation results were reliable.展开更多
We deduce and obtain the law of the motion of the sun by analyzing the law of motion between the moon, the earth, the sun, and the Polaris. Then we obtain the root of the change of earth’s environment from the law. M...We deduce and obtain the law of the motion of the sun by analyzing the law of motion between the moon, the earth, the sun, and the Polaris. Then we obtain the root of the change of earth’s environment from the law. Meanwhile we analyze the form of the present state of the universe movement and the conditions of energy homeostasis. It may provide reference value for related research.展开更多
Hydrogels electrolytes with flexibility and high conductivity have been widely used in kinds of flexible electronics.However,hydrogels always suffer from the inevitable freezing of water at subzero temperatures,which ...Hydrogels electrolytes with flexibility and high conductivity have been widely used in kinds of flexible electronics.However,hydrogels always suffer from the inevitable freezing of water at subzero temperatures,which results in the sacrificing of their electrical properties.Herein,an anti-freezing,flexible hydrogel based on in situ reduction of graphene oxide(GO)and laponite has been developed as electrolyte for high performance supercapacitor and sensitive sensors.The crosslinked GO and laponite in polyacrylamide(PAM)resulted in an enhanced mechanical property,while the in-situ reduction of GO in the hydrogel enhanced the conductivity and diminishes the aggregated of GO.These features guarantee a reliable electro signal as sensor and a high performance of the supercapacitor.Besides,in the process of preparation of reduced graphene oxide(rGO)hydrogel,the addition of ethylene glycol(EG)and KOH,endows the hydrogel antifreeze properties.This anti-freezing electrolyte can be stretched to a strain of 1600%and maintained a specific capacitance of 37.38 F·g^(-1) at-20℃.In addition,the photothermal conversion character of rGO in the hydrogel,endows it’s the potential application in wound healing.The overall merits of the hydrogel will open up a new avenue for sensitive sensor and energy storage device in practical applications.展开更多
In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integrati...In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integration and multi-omics analysis platforms,such techniques have not still been applied widely in rape-seed,an important oil crop worldwide.Here,we report a rapeseed multi-omics database(BnlR;http:/l yanglab.hzau.edu.cn/BnlR),which provides datasets of six omics including genomics,transcriptomics,variomics,epigenetics,phenomics,and metabolomics,as well as numerous"variation-gene expression-phenotype"associations by using multiple statistical methods.In addition,a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets.BnlR is the most comprehensive multi-omics database for rapeseed so far,and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms.展开更多
Photogenerated charge separation and transfer is one of the bottleneck steps in photocatalysis,and efficient charge separation strategies are strongly desired.Here,mimicking the electron transport chain in natural pho...Photogenerated charge separation and transfer is one of the bottleneck steps in photocatalysis,and efficient charge separation strategies are strongly desired.Here,mimicking the electron transport chain in natural photosynthesis,we report the design and fabrication of a charge transfer chain using bismuth-based semiconductor as a proof-of-concept.In view of the thermodynamic energy band positions and structural similarity based on the density functional theory(DFT)analysis,heterostructured combination ofα-Bi_(2)O_(3),perovskite-like Bi_(4)Ti_(3)O_(12),and sillenite Bi12TiO20 was designed for fabrication of charge transfer chain.By tuning the molar ratio of Bi and Ti precursors,the Bi_(4)Ti_(3)O_(12)and Bi12TiO20 particles were formed on the surface ofα-Bi_(2)O_(3)by an insitu transformation process,giving rise to Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)composites with charge transfer chain.We propose that the effective charge transfer is accomplished amongα-Bi_(2)O_(3),Bi12TiO20,and Bi_(4)Ti_(3)O_(12),which significantly improves the photogenerated charge separation and transfer,as indicated by photoluminescene,time-resolved photoluminescene,and electrochemical impedance spectra results.As expected,the Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)shows the superior photocatalytic activity for the degradation of environmental pollutants with high concentration.Even for the refractory pollutants like 4-chlorophenol,the optimal Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)composite shows 28 times higher than that ofα-Bi_(2)O_(3)for photocatalytic degradation,verifying the superiority of photogenerated charge transfer chain in photocatalysis.This work demonstrates the feasibility of the charge transfer chain strategy to boost the photogenerated charge separation,which is of great significance for designing energy and environmental-related materials in heterogonous photocatalysis.展开更多
Background and Aims:Hepatectomy is an effective treatment for selected patients with large hepatocellular carcinoma(HCC).This study aimed to develop a nomogram in-corporating non-tumoral liver volume(non-TLV)and liver...Background and Aims:Hepatectomy is an effective treatment for selected patients with large hepatocellular carcinoma(HCC).This study aimed to develop a nomogram in-corporating non-tumoral liver volume(non-TLV)and liver function markers to predict the patients’overall survival(OS)and disease-free survival(DFS).Methods:Data of 198 consecutive large HCC patients who underwent hepa-tectomy at the Zhongshan Hospital Xiamen University were collected.Another 68 patients from the Mengchao Hepatobil-iary Surgery Hospital served as an external validation cohort.The nomograms were developed based on the independent prognostic factors screened by multivariate Cox regression analyses.Concordance index(C-index),calibration curves,and time-dependent receiver operating characteristic(ROC)curves were used to measure the discrimination and predic-tive accuracy of the models.Results:High HBV DNA level,low non-TLV/ICG,vascular invasion,and a poorly differenti-ated tumor were confirmed as independent risk factors for both OS and DFS.The model established in this study pre-dicted 5-year post-operative survival and DFS in good agree-ment with the actual observation confirmed by the calibra-tion curves.The C-indexes of the nomograms in predicting OS and DFS were 0.812 and 0.823 in the training cohort,0.821 and 0.846 in the internal validation cohort,and 0.724 and 0.755 in the external validation cohort.The areas under the ROC curves(AUCs)of nomograms for predicted OS and DFS at 1,3,and 5 year were 0.85,0.86,0.83 and 0.76,0.76,0.63,respectively.Conclusions:Nomograms with non-TLV/ICG predicted the prognosis of single large HCC patients ac-curately and effectively.展开更多
There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phospha...There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phosphate dehydrogenase(GPDH), encoded by GmGPDHp1 gene, catalyzes the formation of glycerol-3-phosphate(G3 P), an obligate substrate required for TAG biosynthesis.Overexpression of GmGPDHp1 increases soybean seed oil content with high levels of unsaturated fatty acids(FAs), especially oleic acid(C18:1), without detectably affecting growth or seed protein content or seed weight. Based on the lipidomic analyses, we found that the increase in G3 P content led to an elevated diacylglycerol(DAG) pool, in which the Kennedy pathwayderived DAG was mostly increased, followed by PC-derived DAG, thereby promoting the synthesis of TAG containing relatively high proportion of C18:1. The increased G3 P levels induced several transcriptional alterations of genes involved in the glycerolipid pathways. In particular, genes encoding the enzymes responsible for de novo glycerolipid synthesis were largely upregulated in the transgenic lines, in-line with the identified biochemical phenotype. These results reveal a key role for GmGPDHp1-mediated G3 P metabolism in enhancing TAG synthesis and demonstrate a strategy to modify the FA compositions of soybean oils for improved nutrition and biofuel.展开更多
Dear Editor,Genetic variations,which range from single nucleotide polymor-phisms(SNPs)and short insertion/deletions(InDels)to large-scale structural variations(SVs),are the basis of phenotypic diversity.Understanding ...Dear Editor,Genetic variations,which range from single nucleotide polymor-phisms(SNPs)and short insertion/deletions(InDels)to large-scale structural variations(SVs),are the basis of phenotypic diversity.Understanding the effect of genetic variations on traits is critical for uncovering the genetic architecture of various phe-notypes.展开更多
基金Supported by Study of Water Consumption Coefficient in the Irrigation Area of the Yellow River Basin in Qinghai Province(QX2012-019)
文摘The low degree of development and utilization as well as the contradiction between supply and demand of water resources in Huangshui River basin are the main restricting factors of the local agricultural development. The study on the simulation of irrigation water loss based on the VSMB model has very important significance to strengthening regional water management and improving water resource utilization efficiency. Five groundwater wells were set up to carry out the farmland irrigation water infiltration and the experimental study on groundwater dynamic effect. Two soil moisture monitoring sites were set up in two typical plots of Daxia and Guanting irrigation area at the same time and TDR300 was used to monitor four kinds of deep soil moisture( 10 cm,30 cm,50 cm and 70 cm). On this basis,the VSMB model was used to study the irrigation water loss in the irrigation area of Yellow River valley of Qinghai Province,including soil moisture content,the actual evapotranspiration,infiltration,runoff,groundwater buried depth and so on. The results showed that the water consumption caused by soil evaporation and crop transpiration accounted for 46. 4% and 24. 1% of the total precipitation plus irrigation,respectively,and the leakage accounted for 30. 3% and 60. 6% of the total precipitation plus irrigation,respectively,from March 1,2013 to April 30,and from August 1 to September 30. The actual evaporation of the GT- TR1 and GT- TR2 sites in the whole year of 2013 was 632. 6 mm and 646. 9 mm,respectively,and the leakage accounted for 2. 6% and 1. 2% of the total precipitation plus irrigation,respectively. RMSE of the simulation results of the groundwater depth in Daxia irrigation area during the two periods was 92. 3 mm and 27. 7 mm,respectively. And RMSE of the simulation results of the water content of soil profile in the two monitoring sites of Guanting irrigation area was 2. 04% and 5. 81%,respectively,indicating that the simulation results were reliable.
文摘We deduce and obtain the law of the motion of the sun by analyzing the law of motion between the moon, the earth, the sun, and the Polaris. Then we obtain the root of the change of earth’s environment from the law. Meanwhile we analyze the form of the present state of the universe movement and the conditions of energy homeostasis. It may provide reference value for related research.
基金supported by the National Key R&D Program of China(No.2018YFA0209302)the National Natural Science Foundation of China(Nos.21976177,22276191).
文摘Hydrogels electrolytes with flexibility and high conductivity have been widely used in kinds of flexible electronics.However,hydrogels always suffer from the inevitable freezing of water at subzero temperatures,which results in the sacrificing of their electrical properties.Herein,an anti-freezing,flexible hydrogel based on in situ reduction of graphene oxide(GO)and laponite has been developed as electrolyte for high performance supercapacitor and sensitive sensors.The crosslinked GO and laponite in polyacrylamide(PAM)resulted in an enhanced mechanical property,while the in-situ reduction of GO in the hydrogel enhanced the conductivity and diminishes the aggregated of GO.These features guarantee a reliable electro signal as sensor and a high performance of the supercapacitor.Besides,in the process of preparation of reduced graphene oxide(rGO)hydrogel,the addition of ethylene glycol(EG)and KOH,endows the hydrogel antifreeze properties.This anti-freezing electrolyte can be stretched to a strain of 1600%and maintained a specific capacitance of 37.38 F·g^(-1) at-20℃.In addition,the photothermal conversion character of rGO in the hydrogel,endows it’s the potential application in wound healing.The overall merits of the hydrogel will open up a new avenue for sensitive sensor and energy storage device in practical applications.
基金supported by the National Natural Science Foundation of China(32070559)the National Key Research and Development Plan of China(2021YFF1000100)+2 种基金the China Postdoctoral Science Foundation(2022M710875)the Hubei Hongshan Laboratory(2021HSZD004)and the Developing Bioinformatics Platform in Hainan Yazhou Bay Seed Lab(no.JBGS-B21HJ0001).
文摘In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integration and multi-omics analysis platforms,such techniques have not still been applied widely in rape-seed,an important oil crop worldwide.Here,we report a rapeseed multi-omics database(BnlR;http:/l yanglab.hzau.edu.cn/BnlR),which provides datasets of six omics including genomics,transcriptomics,variomics,epigenetics,phenomics,and metabolomics,as well as numerous"variation-gene expression-phenotype"associations by using multiple statistical methods.In addition,a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets.BnlR is the most comprehensive multi-omics database for rapeseed so far,and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms.
基金supported by the National Natural Science Foundation of China(No.22172068)the Natural Science Foundation of Jiangsu Province(No.BK20221485)+2 种基金the Liaoning Revitalization Talents Program(No.XLYC1902065)the Scientific Research Fund of Liaoning Provincial Department of Education(No.LJKMZ20220747)the Talent Scientific Research Fund of LSHU(No.2016XJJ-012).
文摘Photogenerated charge separation and transfer is one of the bottleneck steps in photocatalysis,and efficient charge separation strategies are strongly desired.Here,mimicking the electron transport chain in natural photosynthesis,we report the design and fabrication of a charge transfer chain using bismuth-based semiconductor as a proof-of-concept.In view of the thermodynamic energy band positions and structural similarity based on the density functional theory(DFT)analysis,heterostructured combination ofα-Bi_(2)O_(3),perovskite-like Bi_(4)Ti_(3)O_(12),and sillenite Bi12TiO20 was designed for fabrication of charge transfer chain.By tuning the molar ratio of Bi and Ti precursors,the Bi_(4)Ti_(3)O_(12)and Bi12TiO20 particles were formed on the surface ofα-Bi_(2)O_(3)by an insitu transformation process,giving rise to Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)composites with charge transfer chain.We propose that the effective charge transfer is accomplished amongα-Bi_(2)O_(3),Bi12TiO20,and Bi_(4)Ti_(3)O_(12),which significantly improves the photogenerated charge separation and transfer,as indicated by photoluminescene,time-resolved photoluminescene,and electrochemical impedance spectra results.As expected,the Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)shows the superior photocatalytic activity for the degradation of environmental pollutants with high concentration.Even for the refractory pollutants like 4-chlorophenol,the optimal Bi_(12)TiO_(20)-Bi_(4)Ti_(3)O_(12)/α-Bi_(2)O_(3)composite shows 28 times higher than that ofα-Bi_(2)O_(3)for photocatalytic degradation,verifying the superiority of photogenerated charge transfer chain in photocatalysis.This work demonstrates the feasibility of the charge transfer chain strategy to boost the photogenerated charge separation,which is of great significance for designing energy and environmental-related materials in heterogonous photocatalysis.
基金the grants of the Medical and Health Key project of Xiamen(3502Z20191106).
文摘Background and Aims:Hepatectomy is an effective treatment for selected patients with large hepatocellular carcinoma(HCC).This study aimed to develop a nomogram in-corporating non-tumoral liver volume(non-TLV)and liver function markers to predict the patients’overall survival(OS)and disease-free survival(DFS).Methods:Data of 198 consecutive large HCC patients who underwent hepa-tectomy at the Zhongshan Hospital Xiamen University were collected.Another 68 patients from the Mengchao Hepatobil-iary Surgery Hospital served as an external validation cohort.The nomograms were developed based on the independent prognostic factors screened by multivariate Cox regression analyses.Concordance index(C-index),calibration curves,and time-dependent receiver operating characteristic(ROC)curves were used to measure the discrimination and predic-tive accuracy of the models.Results:High HBV DNA level,low non-TLV/ICG,vascular invasion,and a poorly differenti-ated tumor were confirmed as independent risk factors for both OS and DFS.The model established in this study pre-dicted 5-year post-operative survival and DFS in good agree-ment with the actual observation confirmed by the calibra-tion curves.The C-indexes of the nomograms in predicting OS and DFS were 0.812 and 0.823 in the training cohort,0.821 and 0.846 in the internal validation cohort,and 0.724 and 0.755 in the external validation cohort.The areas under the ROC curves(AUCs)of nomograms for predicted OS and DFS at 1,3,and 5 year were 0.85,0.86,0.83 and 0.76,0.76,0.63,respectively.Conclusions:Nomograms with non-TLV/ICG predicted the prognosis of single large HCC patients ac-curately and effectively.
基金financially supported by National Key R&D Program of China(2016YFD0100201,2016YFD0100500,2016YFD0100300)National Natural Science Foundation of China(U20A2027,31971899,31971968,32070274)+7 种基金Hundred-thousand and million project of“Heilongjiang province for engineering and technology science”soybean breeding technology innovation and new cultivar breeding(2019ZX16B01)Natural Science Foundation of Heilongjiang(ZD2020C007)China Postdoctoral Science Foundation(2019M661243)Postdoctoral Project of Northeast Agricultural University(NEAUBH-19002)International Postdoctoral Exchange Fellowship Program of China Postdoctoral Council(20180004)Heilongjiang Funds for Distinguished Young Scientists(JC2016004,JC2017006)Dongnongxue zhe Project(to Chen Qingshan)Backbone of Young Talent Scholar Project(to Qi Zhaoming,18XG01)of Northeast Agricultural University。
文摘There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phosphate dehydrogenase(GPDH), encoded by GmGPDHp1 gene, catalyzes the formation of glycerol-3-phosphate(G3 P), an obligate substrate required for TAG biosynthesis.Overexpression of GmGPDHp1 increases soybean seed oil content with high levels of unsaturated fatty acids(FAs), especially oleic acid(C18:1), without detectably affecting growth or seed protein content or seed weight. Based on the lipidomic analyses, we found that the increase in G3 P content led to an elevated diacylglycerol(DAG) pool, in which the Kennedy pathwayderived DAG was mostly increased, followed by PC-derived DAG, thereby promoting the synthesis of TAG containing relatively high proportion of C18:1. The increased G3 P levels induced several transcriptional alterations of genes involved in the glycerolipid pathways. In particular, genes encoding the enzymes responsible for de novo glycerolipid synthesis were largely upregulated in the transgenic lines, in-line with the identified biochemical phenotype. These results reveal a key role for GmGPDHp1-mediated G3 P metabolism in enhancing TAG synthesis and demonstrate a strategy to modify the FA compositions of soybean oils for improved nutrition and biofuel.
基金supported by the National Natural Science Foundation of China(32070559)National Key Research and Development Plan of China(2021YFF1000100,2017YFE0104800)Fundamental Research Funds for the Central University HZAU(2662018PY068)。
文摘Dear Editor,Genetic variations,which range from single nucleotide polymor-phisms(SNPs)and short insertion/deletions(InDels)to large-scale structural variations(SVs),are the basis of phenotypic diversity.Understanding the effect of genetic variations on traits is critical for uncovering the genetic architecture of various phe-notypes.