Butyric acid as a renewable resource has become an increasingly attractive alternative to petroleum based fuels.Clostridium tyrobutyricum is well documented as a fermentation strain for the production of acids. Howeve...Butyric acid as a renewable resource has become an increasingly attractive alternative to petroleum based fuels.Clostridium tyrobutyricum is well documented as a fermentation strain for the production of acids. However, it hasbeen reported that butyrate inhibits its growth, and the accumulation of acetate also inhibits biomass synthesis,making production of butyric acid from conventional fermentation processes economically challenging. The presentstudy aimed to identify whether irradiation of C. tyrobutyricum cells makes them more tolerant to butyric acidinhibition and increases the production of butyrate compared with wild type.展开更多
The world is facing severe challenges of sustainable development, which requires the joint effort of the globalscience community to solve. As China continues to grow at a very impressive pace, the state appears acutel...The world is facing severe challenges of sustainable development, which requires the joint effort of the globalscience community to solve. As China continues to grow at a very impressive pace, the state appears acutely awareof the need to expand the Chinese science and technology portfolio to help fuel its growth and keep it sustainable.China also needs to continue on the path to innovations and modernization, focusing on endogenous growth torealize full, coordinated, and sustainable development.展开更多
The world’s pharmaceutical industry is facing the shrink of new drug R&D investment,reduction of the number of new product approval and listed and patent expiration,and the drug production patterns are changing.A...The world’s pharmaceutical industry is facing the shrink of new drug R&D investment,reduction of the number of new product approval and listed and patent expiration,and the drug production patterns are changing.After years of development,China has a very good accumulation on the drug production.Facing the opportunities for change,how to use and play our advantage,breaking the barriers of large foreign pharmaceutical companies,become the key to the future development of China’s pharmaceutical industry.Heavy ion irradiation drug production as a new method plays an important role both in the discovery of the structure of new drugs,high-quality traditional Chinese medicine and Resources of medicinal microorganisms.展开更多
文摘Butyric acid as a renewable resource has become an increasingly attractive alternative to petroleum based fuels.Clostridium tyrobutyricum is well documented as a fermentation strain for the production of acids. However, it hasbeen reported that butyrate inhibits its growth, and the accumulation of acetate also inhibits biomass synthesis,making production of butyric acid from conventional fermentation processes economically challenging. The presentstudy aimed to identify whether irradiation of C. tyrobutyricum cells makes them more tolerant to butyric acidinhibition and increases the production of butyrate compared with wild type.
文摘The world is facing severe challenges of sustainable development, which requires the joint effort of the globalscience community to solve. As China continues to grow at a very impressive pace, the state appears acutely awareof the need to expand the Chinese science and technology portfolio to help fuel its growth and keep it sustainable.China also needs to continue on the path to innovations and modernization, focusing on endogenous growth torealize full, coordinated, and sustainable development.
文摘The world’s pharmaceutical industry is facing the shrink of new drug R&D investment,reduction of the number of new product approval and listed and patent expiration,and the drug production patterns are changing.After years of development,China has a very good accumulation on the drug production.Facing the opportunities for change,how to use and play our advantage,breaking the barriers of large foreign pharmaceutical companies,become the key to the future development of China’s pharmaceutical industry.Heavy ion irradiation drug production as a new method plays an important role both in the discovery of the structure of new drugs,high-quality traditional Chinese medicine and Resources of medicinal microorganisms.
