The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter d...The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter damage by ligation of the bilateral common carotid arteries. Rats received daily intragastric administration of a suspension of Kaixin ]ieyu Fang powder. After 3, 7 and 21 days of treatment, the degree of white matter damage in the cerebral ischemia rat model was alleviated, Bcl-2 protein and mRNA expression in brain tissue increased, and Bax protein and mRNA expression decreased. These results indicate that Kaixin Jieyu Fang can alleviate cere- bral white matter damage, and the underlying mechanism is associated with regulation of Bcl-2/ Bax protein and mRNA expression, which is one of possible mechanism behind the protective effect of Kaixin Jieyu Fang against vascular depression.展开更多
The tea from tea plants,a kind of traditional leaf plant,is deeply loved by people,but the production of tea fruit and its important functional value have been seriously underestimated for a long time.To this end,the ...The tea from tea plants,a kind of traditional leaf plant,is deeply loved by people,but the production of tea fruit and its important functional value have been seriously underestimated for a long time.To this end,the oil plant function and comprehensive utilization value of tea oil from tea fruit were introduced,and a set of new standardized cultivation technique of tea plants that could fully exert the potential of tea seed yield was put forward.The technique could increase the tea seed yield per mu from less than 50kg in traditional tea gardens to more than 200 kg,which broke through the production mode of single leaf picking in traditional tea gardens,gave play to the natural reproductive growth advantages of tea plants,achieved"leaf-seed dual harvest",and promoted the improvement of tea industry quality and efficiency,thereby creating a new path to achieve the"leaf-fruit dual use"of tea plants.展开更多
基金supported by the National Natural Science Foundation of China,No.30672696,81072801the Natural Science Foundation of Beijing in China,No.7093129
文摘The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter damage by ligation of the bilateral common carotid arteries. Rats received daily intragastric administration of a suspension of Kaixin ]ieyu Fang powder. After 3, 7 and 21 days of treatment, the degree of white matter damage in the cerebral ischemia rat model was alleviated, Bcl-2 protein and mRNA expression in brain tissue increased, and Bax protein and mRNA expression decreased. These results indicate that Kaixin Jieyu Fang can alleviate cere- bral white matter damage, and the underlying mechanism is associated with regulation of Bcl-2/ Bax protein and mRNA expression, which is one of possible mechanism behind the protective effect of Kaixin Jieyu Fang against vascular depression.
基金Supported by the Project for the Research of Zhejiang Province,China(LGN18C160009)The Key Science and Technology Program of Jinhua City,China(2018-2-001).
文摘The tea from tea plants,a kind of traditional leaf plant,is deeply loved by people,but the production of tea fruit and its important functional value have been seriously underestimated for a long time.To this end,the oil plant function and comprehensive utilization value of tea oil from tea fruit were introduced,and a set of new standardized cultivation technique of tea plants that could fully exert the potential of tea seed yield was put forward.The technique could increase the tea seed yield per mu from less than 50kg in traditional tea gardens to more than 200 kg,which broke through the production mode of single leaf picking in traditional tea gardens,gave play to the natural reproductive growth advantages of tea plants,achieved"leaf-seed dual harvest",and promoted the improvement of tea industry quality and efficiency,thereby creating a new path to achieve the"leaf-fruit dual use"of tea plants.