不同人种绝经后全身与局部脂肪分布的改变情况

目的为了验证脂肪中心性分布的人种因素；确定白人、黑人与亚洲妇女绝经后脂肪中心性分布的不同。方法横断面研究，通过双能X线吸收法测量全身与局部的脂肪含量并进行线性回归分析。募集了444名，年龄18～94岁的妇女，其中227名白人，128名黑人与89名亚洲人。通过对年龄、体重、身高与全身脂肪校正后，分析男性型与女性型脂肪的分布与躯干／四肢脂肪的比值。结果种族因素与男性型、女性型脂肪及躯干／下肢脂肪比值显著相关（P〈0．O001）。种族-绝经也发现有显著意义（P=0．028）。每一组，局部与全身脂肪水平，特别是男性型脂肪在绝经后妇女中高于绝经前妇女。而且，绝经后男性型脂肪分布在白人有显著意义（P〈0．05），但在黑人与亚洲人中无影响。结论脂肪量与其分布主要由人种决定。绝经的影响在白人中具有显著意义。

Body mass index versus percentage body fat in Chinese, African-American and Caucasian postmenopausal women

Objective: The aim of the study was to investigate in postmenopausal women whether the relationship between percentage body fat (PBF) and body mass index (BMI) differs between Asians living in Beijing (BA) and African-Americans (AA), and Caucasians (Ca) living in New York City. Methods: Healthy postmenopausal women (231 BA; 113 AA, 95 Ca), aged 50-80 years, were studied. Weight, height and PBF by dual energy X-ray absorptiometry (DXA) were measured. The relationship between PBF and BMI was assessed by multiple regression analysis. Results: Race, reciprocal of BMI (1/BMI) and the interaction between race and 1/BMI were all significantly (P<0.05) related to PBF in this sample. The slope of the line relating 1/BMI to PBF was different for BA compared to AA (P=0.01) and Ca (P=0.003) while the slopes for AA and Ca were not different (P>0.05). At lower levels of BMI, Asians tended to have higher PBF comparable to AA and Ca, while at BMI >30 BA tended to have less PBF than the other groups. Conclusion: The relation between PBF and BMI in BA postmenopausal women differs from that of AA and Ca women in this sample.

Regional fat distribution changes with aging in Caucasian,African-American and Asian women

Background:A central pattern of fat distribution in postmenopausal women is regarded as a contributor to the increased risk of developing cardiovascular disease.Both ethnicity and occurrence of menopause appear to influence regional fat distribution.However the influence of ethnicity has been under-investigated.Objective:The objective of this study was to test the hypothesis that centralized fat distribution is influenced by ethnic origin.Furthermore,we hypothesize that the menopause-related changes in central adiposity in Caucasian,African-American and Asian women occur at different rates.Method:Total and regional body fat ratios were measured by whole body dual energy X-ray absorptiometry(DXA)in a cross-sectional study using a general linear regression model.After adjustment for age,weight,height,and total body fat,the android and gynoid fat compartments,and the ratio of trunk/leg fat,were analyzed.Results:Four hundred and forty-four women(227 Caucasian(Ca),128 African-American(AA)and 89 Asian(As))aged 18-94 y were recruited.Race was significantly(P<0.0001)related to the dependent variables:android and gynoid fat,and ratio of trunk/leg adiposity,in all subjects,adjusted by age,weight,height and total body fat.The interaction of race*menopause was also found to be significant(P=0.028).In each group,regional and total body fat levels,and especially android adiposity,were higher in postmenopausal than in premenopausal women.Interestingly,the postmenopausal difference in android fat in Ca was found significant(P<0.05),whereas such differences had no impact in AA and As subjects(NS).Conclusions:The differences in fat mass and its distribution were racially dependent.The impact of menopause was only significant in Ca group.