Biofuels derived from hydrocarbon biosynthetic pathways have attracted increasing attention. Routes to hydrocarbon biofuels are emerging and mainly fall into two categories based on the metabolic pathways utilized： F...Biofuels derived from hydrocarbon biosynthetic pathways have attracted increasing attention. Routes to hydrocarbon biofuels are emerging and mainly fall into two categories based on the metabolic pathways utilized： Fatty acid pathway-based alkanes/alkenes and isoprenoid biosynthetic pathway based terpenes. The primary focus of this review is on recent progress in the application of hydrocarbon biosynthetic pathways for hydrocarbon biofuel production, together with studies on enzymes, including efforts to engineering them for improved performance.展开更多
Serum proteins represent an important class of drug and imaging agent delivery vectors. In this mini- review, key advantages of using serum proteins are discussed, followed by the particular advantages and challenges ...Serum proteins represent an important class of drug and imaging agent delivery vectors. In this mini- review, key advantages of using serum proteins are discussed, followed by the particular advantages and challenges associated with employing soluble folate binding protein. In particular, approaches employing drugs that target folate metabolism are reviewed. Additionally, the slow-onset, tight- binding interaction of folate with folate binding protein and the relationship to a natural oligomerization mechanism is discussed. These unique aspects of folate binding protein suggest interesting applications for the protein as a vector for further drug and imaging agent development.展开更多
文摘Biofuels derived from hydrocarbon biosynthetic pathways have attracted increasing attention. Routes to hydrocarbon biofuels are emerging and mainly fall into two categories based on the metabolic pathways utilized： Fatty acid pathway-based alkanes/alkenes and isoprenoid biosynthetic pathway based terpenes. The primary focus of this review is on recent progress in the application of hydrocarbon biosynthetic pathways for hydrocarbon biofuel production, together with studies on enzymes, including efforts to engineering them for improved performance.
文摘Serum proteins represent an important class of drug and imaging agent delivery vectors. In this mini- review, key advantages of using serum proteins are discussed, followed by the particular advantages and challenges associated with employing soluble folate binding protein. In particular, approaches employing drugs that target folate metabolism are reviewed. Additionally, the slow-onset, tight- binding interaction of folate with folate binding protein and the relationship to a natural oligomerization mechanism is discussed. These unique aspects of folate binding protein suggest interesting applications for the protein as a vector for further drug and imaging agent development.
