We report two patients with orthotopic liver transplantation (OLT) who develop ed a syndrome that fulfilled criteria for definite chronic inflammatory demyelin ating polyradiculoneuropathy (CIDP). One patient had OLT ...We report two patients with orthotopic liver transplantation (OLT) who develop ed a syndrome that fulfilled criteria for definite chronic inflammatory demyelin ating polyradiculoneuropathy (CIDP). One patient had OLT because of alcoholic ci rrhosis and one following hepatitis C induced hepatic failure. Both had immunos uppressive therapy, with cyclosporine and prednisolone in one case and tacrolimu s in the other case. Treatment with intravenous immune globulin (IVIG) significa ntly improved the neuropathy in both patients. In patients with OLT developing d isabling sensorimotor neuropathies, CIDP should be considered as should the use of potentially beneficial immunosuppressive treatment.展开更多
文摘We report two patients with orthotopic liver transplantation (OLT) who develop ed a syndrome that fulfilled criteria for definite chronic inflammatory demyelin ating polyradiculoneuropathy (CIDP). One patient had OLT because of alcoholic ci rrhosis and one following hepatitis C induced hepatic failure. Both had immunos uppressive therapy, with cyclosporine and prednisolone in one case and tacrolimu s in the other case. Treatment with intravenous immune globulin (IVIG) significa ntly improved the neuropathy in both patients. In patients with OLT developing d isabling sensorimotor neuropathies, CIDP should be considered as should the use of potentially beneficial immunosuppressive treatment.
