Ribosome production is vital for every cell,and failure causes human diseases.It is driven by∼200 assembly factors functioning along an ordered pathway from the nucleolus to the cytoplasm.Structural snapshots of biog...Ribosome production is vital for every cell,and failure causes human diseases.It is driven by∼200 assembly factors functioning along an ordered pathway from the nucleolus to the cytoplasm.Structural snapshots of biogenesis intermediates from the earliest 90S pre-ribosomes to mature 40S subunits unravel the mechanisms of small ribosome synthesis.To view this SnapShot,open or download the PDF.展开更多
文摘Ribosome production is vital for every cell,and failure causes human diseases.It is driven by∼200 assembly factors functioning along an ordered pathway from the nucleolus to the cytoplasm.Structural snapshots of biogenesis intermediates from the earliest 90S pre-ribosomes to mature 40S subunits unravel the mechanisms of small ribosome synthesis.To view this SnapShot,open or download the PDF.