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Education-based approach to addressing non-evidence-based practice in preventing NSAID-associated gastrointestinal complications 被引量:5
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作者 Angel Lanas Juan V Esplugues +1 位作者 Javier Zapardiel eduardo sobreviela 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第47期5953-5959,共7页
AIM:To evaluate an evidence-based educational program for improving strategies for prevention of non-steroidal anti-inflammatory drug(NSAID)-associated gastrointestinal(GI)complications. METHODS:Four hundred and fifty... AIM:To evaluate an evidence-based educational program for improving strategies for prevention of non-steroidal anti-inflammatory drug(NSAID)-associated gastrointestinal(GI)complications. METHODS:Four hundred and fifty-six specialists replied to a questionnaire that covered issues related to NSAID-induced adverse effects.They also collected data from their last five consecutive patients before and after they had attended an evidence-based seminar on GI prevention strategies. RESULTS:Four hundred and forty-one of 456 specialists(96.7%)participated in the survey,and 382(83.7%)in the education-based study that recorded data from 3728 patients.The specialists overestimated the risk of GI complications with NSAIDs,underestimated the GI safety profile of coxibs,but were aware of the risk factors and of the current prevention strategies.Proton pump inhibitors were co-prescribed with NSAIDs in>80% of patients with and without risk factors.The educational program had little impact on prescribing habits.CONCLUSION:Specialists are informed of advances in NSAID-associated adverse effects and have high rates of GI-prevention therapy.Our educational program did not alter these rates. 展开更多
关键词 Nonsteroidal anti-inflammatory agents EDUCATION Gastrointestinal diseases Adverse effects Cyclooxygenase 2 inhibitors Proton pump inhibitors
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