In the context of the continuous increase in global grain production,accompanied by a large amount of investment in various pesticides,herbicides,fungicides,and other chemical pesticides.It has caused inevitable envir...In the context of the continuous increase in global grain production,accompanied by a large amount of investment in various pesticides,herbicides,fungicides,and other chemical pesticides.It has caused inevitable environmental problems and food safety problems.Current research suggests that the use of cyclodextrins and their derivatives to protect pesticides can significantly reduce the number of agrochemicals that pollute the environment.Using the cavity properties of cyclodextrins,we can refer to the similar way in which drug molecules make cyclodextrins and cyclodextrin polymers to form inclusion compounds.Overall,β-cyclodextrin and its derivatives are used as a new pesticide excipient to improve the stability of pesticides,prevent their oxidation and decomposition,improve the solubility and bioavailability of pesticides,reduce the toxic side effects of drugs,and mask the odour of drugs.In this review,we focus on summarising the recent research progress ofβ-cyclodextrins and their derivatives in pesticides and other fields,and provide a systematic classification ofβ-cyclodextrin polymers,as well as new synthesis methods and techniques in various applications.Finally,the future development of cyclodextrin-like polymers is foreseen,and issues arising from the research are discussed and addressed in depth.展开更多
基金supported by the National Key Research and Development Program(2021YFA0716702)the National Natural Science Foundation of China(22071074,21772055)the 111 Project(B17019)。
文摘In the context of the continuous increase in global grain production,accompanied by a large amount of investment in various pesticides,herbicides,fungicides,and other chemical pesticides.It has caused inevitable environmental problems and food safety problems.Current research suggests that the use of cyclodextrins and their derivatives to protect pesticides can significantly reduce the number of agrochemicals that pollute the environment.Using the cavity properties of cyclodextrins,we can refer to the similar way in which drug molecules make cyclodextrins and cyclodextrin polymers to form inclusion compounds.Overall,β-cyclodextrin and its derivatives are used as a new pesticide excipient to improve the stability of pesticides,prevent their oxidation and decomposition,improve the solubility and bioavailability of pesticides,reduce the toxic side effects of drugs,and mask the odour of drugs.In this review,we focus on summarising the recent research progress ofβ-cyclodextrins and their derivatives in pesticides and other fields,and provide a systematic classification ofβ-cyclodextrin polymers,as well as new synthesis methods and techniques in various applications.Finally,the future development of cyclodextrin-like polymers is foreseen,and issues arising from the research are discussed and addressed in depth.
