A recent study published in Nature by Zoch et al.identifies a novel MIWI2-associated protein SPOCD1 and shows its requirement for piRNA-guided young transposable elements(TEs)methylation and silencing.1 This research ...A recent study published in Nature by Zoch et al.identifies a novel MIWI2-associated protein SPOCD1 and shows its requirement for piRNA-guided young transposable elements(TEs)methylation and silencing.1 This research provided the first mechanistic insights into how piRNA directs de novo DNA methylation in male mammals(Fig.1).展开更多
基金supported by the Startup Funding to E.Z.S.from the Westlake Education Foundation.
文摘A recent study published in Nature by Zoch et al.identifies a novel MIWI2-associated protein SPOCD1 and shows its requirement for piRNA-guided young transposable elements(TEs)methylation and silencing.1 This research provided the first mechanistic insights into how piRNA directs de novo DNA methylation in male mammals(Fig.1).
