With the rapid development of stem cell-related therapies and regenerative medicine,the clinical application of stem cell products is on the rise.However,ensuring the effectiveness of these products after storage and ...With the rapid development of stem cell-related therapies and regenerative medicine,the clinical application of stem cell products is on the rise.However,ensuring the effectiveness of these products after storage and transportation remains a challenge in the transformation to clinical trials.Cryopreservation technology allows for the long-term storage of cells while ensuring viability,making it a top priority for stem cell preservation.The field of cryopreservationrelated engineering technologies is thriving,and this review provides an overview of the background and basic principles of cryopreservation.It then delves into the main bioengineering technologies and strategies used in cryopreservation,including photothermal and electromagnetic rewarming,microencapsulation,and synergetic ice inhibition.Finally,the current challenges and future prospects in the field of efficient cryopreservation of stem cells are summarized and discussed.展开更多
Combustion instability is a very important issue in the development of the propulsion systems used in aerospace. It is very important to associate the high frequency combustion instabilities with the acoustic characte...Combustion instability is a very important issue in the development of the propulsion systems used in aerospace. It is very important to associate the high frequency combustion instabilities with the acoustic characteristics of the combustion chamber. In this paper, the effects of various baffle injectors which were installed on the injector faceplate on the first-order tangential acoustic mode were investigated theoretically and experimentally. The effects of the gap between adjacent injectors on the first-order tangential acoustic mode in a cylindrical chamber were considered. The acoustic admittance of the injectors was derived. The results showed that the amplitude and frequency of the first-order tangential acoustic mode increase with the increase in the gap between adjacent injectors, but decrease with the increase in the number and height of the baffles.The baffle injectors have a greater influence on the amplitude and frequency of the first-order tangential acoustic mode than the baffle blades.展开更多
基金supported by the National Natural Science Foundation of China(No.82172114)the Anhui Provincial Natural Science Foundation for Distinguished Young Scholars(No.2108085J37)the National Key Research and Development Program of China(2022YFC2703000).
文摘With the rapid development of stem cell-related therapies and regenerative medicine,the clinical application of stem cell products is on the rise.However,ensuring the effectiveness of these products after storage and transportation remains a challenge in the transformation to clinical trials.Cryopreservation technology allows for the long-term storage of cells while ensuring viability,making it a top priority for stem cell preservation.The field of cryopreservationrelated engineering technologies is thriving,and this review provides an overview of the background and basic principles of cryopreservation.It then delves into the main bioengineering technologies and strategies used in cryopreservation,including photothermal and electromagnetic rewarming,microencapsulation,and synergetic ice inhibition.Finally,the current challenges and future prospects in the field of efficient cryopreservation of stem cells are summarized and discussed.
基金the National Natural Science Foundation of China (Nos. 51806057, 52005152 and 12042211)the Natural Science Foundation of Hebei, China (Nos. E2019202460 and E2019202451)+2 种基金Tianjin Science and Technology Project, China (No. 19YFZCSF00850)the Key Research Program Projects of Hebei Province, China (No. 19274502D)the Industrial Technology Research of Hebei University of Technology, China (No. ZBYJY201902)
文摘Combustion instability is a very important issue in the development of the propulsion systems used in aerospace. It is very important to associate the high frequency combustion instabilities with the acoustic characteristics of the combustion chamber. In this paper, the effects of various baffle injectors which were installed on the injector faceplate on the first-order tangential acoustic mode were investigated theoretically and experimentally. The effects of the gap between adjacent injectors on the first-order tangential acoustic mode in a cylindrical chamber were considered. The acoustic admittance of the injectors was derived. The results showed that the amplitude and frequency of the first-order tangential acoustic mode increase with the increase in the gap between adjacent injectors, but decrease with the increase in the number and height of the baffles.The baffle injectors have a greater influence on the amplitude and frequency of the first-order tangential acoustic mode than the baffle blades.
