Nephroureterectomy is currently the criterion-standard treatment for high-grade upper tract urothelial carcinoma(UTUC).Current guidelines and expert opinions propose some exceptions to this approach based on patient c...Nephroureterectomy is currently the criterion-standard treatment for high-grade upper tract urothelial carcinoma(UTUC).Current guidelines and expert opinions propose some exceptions to this approach based on patient characteristics,disease status,and function of the contralateral kidney.We present a rare case of a patient with horseshoe kidney,bilateral large nephrolithiasis,high-grade UTUC in one moiety,and relative parenchymal thinning of the contralateral side.The patient was treated with a percutaneous,minimally invasive,nephron sparing approach.The patient also had intracollecting system instillations of gemcitabine and docetaxel.Minimally invasive percutaneous resection of high-grade UTUC is a safe procedure in select cases.Current guidelines may not apply to all patients;unique scenarios with UTUC may require personalized decision-making and treatment at specialized centers.展开更多
文摘Nephroureterectomy is currently the criterion-standard treatment for high-grade upper tract urothelial carcinoma(UTUC).Current guidelines and expert opinions propose some exceptions to this approach based on patient characteristics,disease status,and function of the contralateral kidney.We present a rare case of a patient with horseshoe kidney,bilateral large nephrolithiasis,high-grade UTUC in one moiety,and relative parenchymal thinning of the contralateral side.The patient was treated with a percutaneous,minimally invasive,nephron sparing approach.The patient also had intracollecting system instillations of gemcitabine and docetaxel.Minimally invasive percutaneous resection of high-grade UTUC is a safe procedure in select cases.Current guidelines may not apply to all patients;unique scenarios with UTUC may require personalized decision-making and treatment at specialized centers.
