基于中医药文化和健康旅游视角提出张仲景文化品牌建设对策

当今,中医药文化和健康旅游走向融合,有着内在的必然依据,它们孕育出的中医药健康旅游新业态给中医药文化发展和旅游业的创新注入了新的活力。作为中医药产业文化代表的张仲景文化,应抓住机遇,借助健康旅游实现张仲景品牌建设的新突破。主要建设策略有:积极推出以张仲景等中华名医事迹为题材的图书或影视剧;将中药材种植基地开辟为特色旅游观光园;创立中医药文化研究及传播基地,建设学、疗、游为一体的中医药疗养旅游基地;利用信息技术和文化媒体平台将张仲景中医药学绍介到千家万户。

芒柄花黄素改善脂多糖诱导的小鼠抑郁样行为和神经炎症的作用研究

目的:观察芒柄花黃素(formononetin,FMN)对脂多糖(lipopolysaccharide,LPS)诱导的小鼠抑郁样行为和神经炎症的影响。方法:雄性ICR小鼠随机分为正常组、LPS组、帕罗西江组(20 mg·kg^(-1))、FMN低剂量组(20 mg·kg^(-1)),FMN高剂量组(40 mg·kg^(-1)),每组8只,灌胃给药14天后采用糖水偏好实验(sucrose preference test,SPT)、悬尾实验(tail suspension test,TST)和旷场实验(open field test,OFT)观察小鼠抑郁样行为;采用晦联免疫吸附测定实验(enzyme-linked immunosorbent assay,ELISA)和实时荧光定量聚合晦链式反应实验(real-time quantitative polymerase chain reaction,qRT-PCR)测定小鼠海马组织中白细胞介素-6(interleukin-6,IL-6)、IL-1β和肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)的蛋白和mRNA表达水平;采用免疫荧光染色观察小鼠海马组织中小胶质细胞钙结合蛋白-1(ionized calcium binding adapter molecule1,Iba-1)的表达水平以评价小胶质细胞活化水平。结果:与正常组相比,LPS组小鼠糖水偏好率、中心区域活动时间、中心区域活动距离、进入中心区域的次数显著下降(P<0.01),TST不动时间显著延长(P<0.05),海马组织IL-6、IL-1β和TNF-α蛋白及mRNA表达水平显著升高(P<0.01),海马组织CA1、CA3和DG区域Iba-1荧光强度显著增加(P<0.01)。与LPS组相比,FMN组小鼠糖水偏好率、中心区域活动时间、中心区域活动距离和进入中心区域的次数均显著升高(P<0.05或P<0.01),TST不动时间显著缩短(P<0.01),海马组织IL-6、IL-1β和TNF-α蛋白及mRNA表达水平显著降低(P<0.05或P<0.01),海马组织CA1、CA3和DG区域Iba-1荧光强度显著降低(P<0.01)。结论:FMN可能通过抑制LPS诱导的小胶质细胞活化,减轻海马神经炎症,改善小鼠的抑郁样行为。

Publication Statement of Chinese Medicine and Natural Products

Traditional Chinese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advantageous discipline for our country's foreign exchanges.With the development of the times,TCM journals are becoming more"specialized"and"characterized"and the need to"go abroad"is becoming more and more urgent.Scientific and technological journals in English may lead the direction of scientific research,gather scientific and technological strength and innovative results in the world,which plays an important role in enhancing the country's cultural strength and innovation motivation.In order to expand the academic influence of TCM journals in the world and guide the vast number of scientific and technological workers to write papers on motherland,the establishment and publication of TCM English journal is imperative.With the strong support from relevant higher-level departments and the great help from peers of scientific and technological journals,Chinese Medicine and Natural Products(CMNP)has been successfully founded.

Publication Statement of Chinese Medicine and Natural Products

Traditional Chinese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advantageous discipline for our country's foreign exchanges.

Publication Statement of Chinese Medicine and Natural Products

Traditional Chinese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advantageous discipline for our country,s foreign exchanges.With the development of the times,TCM journals are becoming more"specialized"and Hcharacterizedn and the need to ngo abroad"is becoming more and more urgent.

Publication Statement of Chinese Medicine and Natural Products

Traditional Chinese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advantageous discipline for our country's foreign exchanges.With the development of the times,TCM journals are becoming more"specialized"and"characterized"and the need to"go abroad"is becoming more and more urgent.

Publication Statement of Chinese Medicine and Natural Products

Traditional Chpnese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advanta-geous discipline for our country's foreign exchanges.With the development of the times,TCM journals are becoming more"specialized"and"characterized"and the need to"go abroad"is becoming more and more urgent.English scientific and technological journals may lead the direction of scientifie research,gather scientifie and technological strength and innovative results in the world,which plays an important role in enhaneing the country's cultural strength and innovation motivation.In order to expand the academic influence of TCM joumals in the world and guide the vast number of scientifie and technological workers to write papers on motherland,the establishment and publication of TCM English journal is imperative.w ith the strong support from relevant higher-level departments and the great help from peers of seientifie and technological journals,Chinese Medicine and Natural Products(CMNP)has been scessfully founded.

Publication Statement of Chinese Medicine and Natural Products

Traditional Chinese medicine(TCM)is a treasure of the Chinese nation.It contains rich philosophical thoughts and humanistic spirit,which is an important manifestation of our country's cultural soft power and also an advantageous discipline for our country's foreign exchanges.With the development of the times,TCM journals are becoming more"specialized"and"characterized"and lhe need to"go abroad"is becoming more and more urgent.English scientific and technological journals may lead the direction of scientific research,gather scientific and technological strength and innovative results in the world.