The authors describe the case of a six-year-old girl with Ehlers-Danlos syndrome associated to bilateral symmetrical frontal polymicrogyria.Several extracellular matrix components, including collagen, are directly imp...The authors describe the case of a six-year-old girl with Ehlers-Danlos syndrome associated to bilateral symmetrical frontal polymicrogyria.Several extracellular matrix components, including collagen, are directly implicated in the neuronal migration.We think that a defect in collagen or in another extracellular matrix protein during fetal development could result in this association.展开更多
文摘The authors describe the case of a six-year-old girl with Ehlers-Danlos syndrome associated to bilateral symmetrical frontal polymicrogyria.Several extracellular matrix components, including collagen, are directly implicated in the neuronal migration.We think that a defect in collagen or in another extracellular matrix protein during fetal development could result in this association.
