Secundum atrial septal defect(ASD)repres-ents one of the most common congenital heart diseases,accounting for up to 10%of all congenital heart defects.It is often diagnosed in adulthood due to the absence of clinical ...Secundum atrial septal defect(ASD)repres-ents one of the most common congenital heart diseases,accounting for up to 10%of all congenital heart defects.It is often diagnosed in adulthood due to the absence of clinical symptoms.[1]By the age of 40 years,90%of untreated patients have symptoms of exertional dyspnea,fatigue,pal-pitation,sustained arrhythmia,or even evidence of heart failure.展开更多
Catheter-based closure of patent foramen ovale(PFO)is more effective than medical therapy in the prevention of recurrent stroke[1].It is likely that a proportion of patients evaluated for potential transcatheter PFO c...Catheter-based closure of patent foramen ovale(PFO)is more effective than medical therapy in the prevention of recurrent stroke[1].It is likely that a proportion of patients evaluated for potential transcatheter PFO closure has actually different anatomical variants particularly common in the right atrium such as eustachian valve,Chiari network,Thebesian valve and Crista Terminalis.Notably,the eustachian valve may represent an increased risk factor for left circulation thromboembolism beyond that associated with PFO size and shunting.Such patients may benefit the most from percutaneous closure procedure.展开更多
文摘Secundum atrial septal defect(ASD)repres-ents one of the most common congenital heart diseases,accounting for up to 10%of all congenital heart defects.It is often diagnosed in adulthood due to the absence of clinical symptoms.[1]By the age of 40 years,90%of untreated patients have symptoms of exertional dyspnea,fatigue,pal-pitation,sustained arrhythmia,or even evidence of heart failure.
文摘Catheter-based closure of patent foramen ovale(PFO)is more effective than medical therapy in the prevention of recurrent stroke[1].It is likely that a proportion of patients evaluated for potential transcatheter PFO closure has actually different anatomical variants particularly common in the right atrium such as eustachian valve,Chiari network,Thebesian valve and Crista Terminalis.Notably,the eustachian valve may represent an increased risk factor for left circulation thromboembolism beyond that associated with PFO size and shunting.Such patients may benefit the most from percutaneous closure procedure.
