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对瑞典早产儿预防性应用限制性帕利珠单抗研究
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作者 Navér L. Eriksson M. +1 位作者 ewald u. 平智广 《世界核心医学期刊文摘(儿科学分册)》 2005年第4期12-12,共1页
目的:1999年帕利珠单抗(Synagis(?))在瑞典注册,用于预防早产儿呼吸道合胞病毒(RSV)感染。由于费用高和人们对其有效性了解有限,怎样和何时应用就成了人们讨论的问题。于是2000年瑞典制定了帕利珠单抗使用指南。本研究就是为了评价该指... 目的:1999年帕利珠单抗(Synagis(?))在瑞典注册,用于预防早产儿呼吸道合胞病毒(RSV)感染。由于费用高和人们对其有效性了解有限,怎样和何时应用就成了人们讨论的问题。于是2000年瑞典制定了帕利珠单抗使用指南。本研究就是为了评价该指南。方法:2000-2002年两次RSV流行期间在全国范围内进行了前瞻性研究。 展开更多
关键词 预防性应用 呼吸道合胞病毒 使用指南 单抗治疗 SWEDISH admitted valuate PREMATURE 预防性治疗 慢性肺病
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对低出生体重儿单独母乳喂养的出生后专业咨询:一个随机、对照试验
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作者 Agrasada G.V. Gustafsson J. +2 位作者 Kylberg E. ewald u. 郭战宏 《世界核心医学期刊文摘(儿科学分册)》 2005年第11期24-25,共2页
Aim: Exclusive breastfeeding increases survival and optimizes growth of low-birthweight (LBW) infants. If supported, mothers can overcome the unique difficulties associated with breastfeeding from birth to 6 mo. We te... Aim: Exclusive breastfeeding increases survival and optimizes growth of low-birthweight (LBW) infants. If supported, mothers can overcome the unique difficulties associated with breastfeeding from birth to 6 mo. We tested the efficacy of postnatal peer counselling among first-time mothers that aimed to increase exclusive breastfeeding of term LBW infants. Methods: In a Manila hospital, 204 mothers were randomized into three groups. Two intervention groups receiving home-based counselling visits, one by counsellors trained in breastfeeding counselling (n = 68), the other by counsellors trained in general childcare (n = 67), were compared with a control group of mothers (n = 69) who did not receive counselling. Results: Eighty-eight per cent of the participating pairs completed the trial. At 6 mo, 44%of the breastfeeding counselled mothers, 7%childcare-counselled mothers and none of the mothers in the control group were exclusively breastfeeding. More mothers in the breastfeeding counselled group than in the other groups were still breastfeeding at 6 mo. Twenty-four infants who were exclusively breastfed for 6 mo did not have any diarrhoea. All groups had improved mean weight-for-age Z-scores at 6 mo. Conclusion: This study has provided fundamental evidence of successful intervention to achieve 6mo of exclusive breastfeeding among term LBW infants. By improving health outcomes, enhanced breastfeeding offers a distinct possibility of disrupting the intergenerational cycle of undernourished women giving birth to LBW infants. 展开更多
关键词 母乳喂养 对照试验 专业咨询 出生后 儿童保健 生长发育 干预组 咨询员 一所 咨询组
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