On the basis of water-balance equation in Dongting Lake and Xiang Zi Yuan-Li River drainage areas, a possib1e flood height relating to the rainfall precipitation in these areas has been inferred. According to the floo...On the basis of water-balance equation in Dongting Lake and Xiang Zi Yuan-Li River drainage areas, a possib1e flood height relating to the rainfall precipitation in these areas has been inferred. According to the flood simulation, some synthetic maintenance strategies to prevent future catastrophic f1oods in Dongting Lake drainage area have been also presented.展开更多
目的分析未行髌骨置换的全膝关节置换(total knee arthroplasty,TKA)术后髌骨倾斜角对疗效的影响。方法回顾性分析2020年10月至2021年10月于南京医科大学第一附属医院骨科接受TKA而未行髌骨置换的143例终末期膝关节骨关节炎患者,男32例...目的分析未行髌骨置换的全膝关节置换(total knee arthroplasty,TKA)术后髌骨倾斜角对疗效的影响。方法回顾性分析2020年10月至2021年10月于南京医科大学第一附属医院骨科接受TKA而未行髌骨置换的143例终末期膝关节骨关节炎患者,男32例、女111例,年龄(68.44±6.79)岁(范围52~86岁)。根据术后髌骨倾斜角的大小分为三组:倾斜角<5°为轻度倾斜组(97例)、5°≤倾斜角<10°为中度倾斜组(31例)、倾斜角≥10°为重度倾斜组(15例)。术后3、6、12个月在门诊进行随访,观察并记录患者的膝关节疼痛视觉模拟评分(visual analogue score,VAS)、美国特种外科医院(Hospital for Special Surgery,HSS)评分及髌骨Feller评分,比较不同髌骨倾斜程度组患者术后膝关节疼痛及功能。结果所有患者均获得随访,随访时间为(1.16±0.23)年(范围1.0~2.0年)。患者基线资料的组间差异无统计学意义。三组患者手术前后膝关节VAS评分组内比较的差异均有统计学意义(F=51.12,P<0.001;F=36.90,P<0.001;F=15.76,P<0.001),术后3、6、12个月的膝关节VAS评分均小于术前,差异有统计学意义(P<0.05)。重度倾斜组术后3、6、12个月的膝关节VAS评分均大于轻度组和中度组,差异有统计学意义(P<0.05)。三组患者手术前后膝关节HSS评分组内比较的差异均有统计学意义(F=81.12,P<0.001;F=36.05,P<0.001;F=32.93,P<0.001),术后3、6、12个月的膝关节HSS评分均大于术前,差异有统计学意义(P<0.05);重度倾斜组术后3、6、12个月的膝关节HSS评分均小于轻度组和中度组,差异有统计学意义(P<0.05)。三组患者手术前后髌骨Feller评分组内比较的差异均有统计学意义(F=88.81,P<0.001;F=49.59,P<0.001;F=37.40,P<0.001),术后3、6、12个月的髌骨Feller评分均大于术前,差异有统计学意义(P<0.05);重度倾斜组术后3、6、12个月的髌骨Feller评分小于轻度组和中度组,差异有统计学意义(P<0.05)。结论未行髌骨置换的TKA术后遗留髌骨倾斜角会增加膝关节疼痛,限制关节功能。展开更多
An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunab...An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.展开更多
文摘On the basis of water-balance equation in Dongting Lake and Xiang Zi Yuan-Li River drainage areas, a possib1e flood height relating to the rainfall precipitation in these areas has been inferred. According to the flood simulation, some synthetic maintenance strategies to prevent future catastrophic f1oods in Dongting Lake drainage area have been also presented.
文摘目的探讨术前髌骨倾斜角对全膝关节置换(total knee arthroplasty,TKA)术后临床疗效的影响。方法回顾性分析南京医科大学第一附属医院2020年10月至2022年9月因膝关节骨关节炎行TKA(术中未行髌骨置换)的患者277例,男72例、女205例,年龄(69.16±6.77)岁(范围52~87岁),体质指数(27.01±3.81)kg/m^(2)(范围18.14~39.01 kg/m^(2))。根据术前髌骨倾斜角的大小将患者分为三组:倾斜角<5°为轻度倾斜组、5°≤倾斜角<10°为中度倾斜组、倾斜角≥10°为重度倾斜组。轻度组103例、中度组137例、重度组37例。比较手术前后膝前疼痛视觉模拟评分(visual analogue score,VAS)、美国特种外科医院(Hospital for Special Surgery,HSS)评分及髌骨Feller评分。结果所有患者均获得随访,随访时间为(15.73±3.06)个月(范围12~22个月)。术前髌骨倾斜角为6.86°±3.55°,术后改善至3.63°±2.61°,差异有统计学意义(t=19.086,P<0.001)。轻度组、中度组及重度组术后髌骨倾斜角均变小,与术前比较差异有统计学意义(P<0.05)。三组患者术后膝前VAS评分均降低,与术前比较差异有统计学意义,其中术后3、6、12个月的膝前VAS评分均小于术前;术后6、12个月组间比较差异均有统计学意义(P<0.05),重度组膝前VAS评分为(2.59±0.55)分、(2.03±0.55)分,大于轻度组的(2.15±0.38)分、(1.57±0.50)分和中度组的(2.19±0.49)分、(1.67±0.61)分。三组患者术后HSS评分均增加,与术前比较差异有统计学意义(P<0.05),其中术后3、6、12个月的HSS评分均大于术前。术后6、12个月组间比较差异均有统计学意义(P<0.05),重度组HSS评分为(86.27±2.04)分、(87.73±2.28)分,小于轻度组的(89.02±2.33)分、(89.83±1.48)分和中度组的(88.77±2.83)分、(89.52±1.95)分。三组患者术后髌骨Feller评分均增加,与术前比较差异有统计学意义(P<0.05),其中术后3、6、12个月的髌骨Feller评分均大于术前。术后6、12个月组间比较差异均有统计学意义(P<0.05),重度组髌骨Feller评分为(18.32±1.99)分、(20.32±1.60)分,小于轻度组的(20.92±1.01)分、(23.07±1.39)分和中度组的(20.91±1.95)分、(22.69±1.59)分。结论未行髌骨置换的TKA术前髌骨倾斜角增大可导致术后膝前疼痛、膝关节功能降低。
文摘目的分析未行髌骨置换的全膝关节置换(total knee arthroplasty,TKA)术后髌骨倾斜角对疗效的影响。方法回顾性分析2020年10月至2021年10月于南京医科大学第一附属医院骨科接受TKA而未行髌骨置换的143例终末期膝关节骨关节炎患者,男32例、女111例,年龄(68.44±6.79)岁(范围52~86岁)。根据术后髌骨倾斜角的大小分为三组:倾斜角<5°为轻度倾斜组(97例)、5°≤倾斜角<10°为中度倾斜组(31例)、倾斜角≥10°为重度倾斜组(15例)。术后3、6、12个月在门诊进行随访,观察并记录患者的膝关节疼痛视觉模拟评分(visual analogue score,VAS)、美国特种外科医院(Hospital for Special Surgery,HSS)评分及髌骨Feller评分,比较不同髌骨倾斜程度组患者术后膝关节疼痛及功能。结果所有患者均获得随访,随访时间为(1.16±0.23)年(范围1.0~2.0年)。患者基线资料的组间差异无统计学意义。三组患者手术前后膝关节VAS评分组内比较的差异均有统计学意义(F=51.12,P<0.001;F=36.90,P<0.001;F=15.76,P<0.001),术后3、6、12个月的膝关节VAS评分均小于术前,差异有统计学意义(P<0.05)。重度倾斜组术后3、6、12个月的膝关节VAS评分均大于轻度组和中度组,差异有统计学意义(P<0.05)。三组患者手术前后膝关节HSS评分组内比较的差异均有统计学意义(F=81.12,P<0.001;F=36.05,P<0.001;F=32.93,P<0.001),术后3、6、12个月的膝关节HSS评分均大于术前,差异有统计学意义(P<0.05);重度倾斜组术后3、6、12个月的膝关节HSS评分均小于轻度组和中度组,差异有统计学意义(P<0.05)。三组患者手术前后髌骨Feller评分组内比较的差异均有统计学意义(F=88.81,P<0.001;F=49.59,P<0.001;F=37.40,P<0.001),术后3、6、12个月的髌骨Feller评分均大于术前,差异有统计学意义(P<0.05);重度倾斜组术后3、6、12个月的髌骨Feller评分小于轻度组和中度组,差异有统计学意义(P<0.05)。结论未行髌骨置换的TKA术后遗留髌骨倾斜角会增加膝关节疼痛,限制关节功能。
基金supported by the National Natural Science Foundation of China (20974028, 20974098, and 21174120)the National Basic Research Program of China (2009CB623605)+1 种基金the Research Grants Council of Hong Kong (603509, HKUST2/CRF/10, 604711, and N_HKUST620/11)B.Z.T. thanks the support from the Cao Guangbiao Foundation of Zhejiang University
文摘An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.