A new method is proposed for slope optimization design based on the limit curve method, where the slope is in the limit equilibrium state when the limit slope curve determined by the slip-line field theory and the slo...A new method is proposed for slope optimization design based on the limit curve method, where the slope is in the limit equilibrium state when the limit slope curve determined by the slip-line field theory and the slope intersect at the toe of the slope. Compared with the strength reduction (SR) method, finite element limit analysis method, and the SR method based on Davis algorithm, the new method is suitable for determining the slope stability and limit slope angle (LSA). The optimal slope shape is determined based on a series of slope heights and LSA values, which increases the LSA by 2.45°-11.14° and reduces an invalid overburden amount of rocks by 9.15%, compared with the space mechanics theory. The proposed method gives the objective quantification index of instability criterion, and results in a significant engineering economy.展开更多
目的旨在分析中老年患者体位性高血压与尿微量白蛋白排泄率及左心室质量指数的相关关系。方法选取2018年1月一2019年7月至杭州市第三人民医院就诊的中老年原发性高血压患者556例为研究对象,其中观察组(125例)为体位性血压增高(即直立性...目的旨在分析中老年患者体位性高血压与尿微量白蛋白排泄率及左心室质量指数的相关关系。方法选取2018年1月一2019年7月至杭州市第三人民医院就诊的中老年原发性高血压患者556例为研究对象,其中观察组(125例)为体位性血压增高(即直立性高血压)的患者,收缩压变化低于20 mm Hg(1 mm Hg=0.133 kPa)即直立性血压正常的患者为对照组(431例);评价的内容包括24h尿微量白蛋白排泄率和左心室质量指数以及两者与患者体位性高血压的关联。结果观察组尿微量白蛋白排泄率[(22.3±3.1)mg/24 h]和左心室质量指数[(111.3±5.8)g/m^2]较对照组[(14.2±3.7)mg/24 h.(94.8±5.7)g/m^2]均显著增加,差异有统计学意义(均P<0.001);相关性分析显示直立性性收缩压、直立性性舒张压均与尿微量白蛋白排泄率和左心室质量指数呈线性正相关关系,差异具有统计学意义(均P<0.05);回归方程分别为Y=30.62±0.40X;Y=25.95±0.90X;Y=26.02±0.53X;Y=27.88±1.33X。结论中老年原发性高血压患者体位性血压增高可能与尿微量白蛋白排泄率与左心室质量指数的异常之间存在相关关系,提示可能存在靶器官的损害,临床实践中应予以注意,早期进行干预。展开更多
基金Project(JJKH20180450KJ)supported by Education Department of Jilin Province,ChinaProject(20166008)supported by the Science and Technology Bureau of Jilin Province,China
文摘A new method is proposed for slope optimization design based on the limit curve method, where the slope is in the limit equilibrium state when the limit slope curve determined by the slip-line field theory and the slope intersect at the toe of the slope. Compared with the strength reduction (SR) method, finite element limit analysis method, and the SR method based on Davis algorithm, the new method is suitable for determining the slope stability and limit slope angle (LSA). The optimal slope shape is determined based on a series of slope heights and LSA values, which increases the LSA by 2.45°-11.14° and reduces an invalid overburden amount of rocks by 9.15%, compared with the space mechanics theory. The proposed method gives the objective quantification index of instability criterion, and results in a significant engineering economy.
文摘目的旨在分析中老年患者体位性高血压与尿微量白蛋白排泄率及左心室质量指数的相关关系。方法选取2018年1月一2019年7月至杭州市第三人民医院就诊的中老年原发性高血压患者556例为研究对象,其中观察组(125例)为体位性血压增高(即直立性高血压)的患者,收缩压变化低于20 mm Hg(1 mm Hg=0.133 kPa)即直立性血压正常的患者为对照组(431例);评价的内容包括24h尿微量白蛋白排泄率和左心室质量指数以及两者与患者体位性高血压的关联。结果观察组尿微量白蛋白排泄率[(22.3±3.1)mg/24 h]和左心室质量指数[(111.3±5.8)g/m^2]较对照组[(14.2±3.7)mg/24 h.(94.8±5.7)g/m^2]均显著增加,差异有统计学意义(均P<0.001);相关性分析显示直立性性收缩压、直立性性舒张压均与尿微量白蛋白排泄率和左心室质量指数呈线性正相关关系,差异具有统计学意义(均P<0.05);回归方程分别为Y=30.62±0.40X;Y=25.95±0.90X;Y=26.02±0.53X;Y=27.88±1.33X。结论中老年原发性高血压患者体位性血压增高可能与尿微量白蛋白排泄率与左心室质量指数的异常之间存在相关关系,提示可能存在靶器官的损害,临床实践中应予以注意,早期进行干预。