The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(MSCs),generally referred to as the MSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative di...The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(MSCs),generally referred to as the MSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative diseases.MSCs secretome contains both common and disease specific cytokines and modulators that can be beneficial against a wide range of chronic diseases.Herein,we discuss the MSCs secretome composition profile and its translational applicability and the challenges surrounding its use in clinical settings.展开更多
文摘The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells(MSCs),generally referred to as the MSCs derived secretome,has substantial potential for the treatment of many chronic and degenerative diseases.MSCs secretome contains both common and disease specific cytokines and modulators that can be beneficial against a wide range of chronic diseases.Herein,we discuss the MSCs secretome composition profile and its translational applicability and the challenges surrounding its use in clinical settings.
