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甲状腺球蛋白对甲状腺未全部切除的分化型甲状腺癌术后残留或复发的诊断价值 被引量:9
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作者 费伦 王培云 +5 位作者 陈建军 徐炜炜 汪仕辉 李加城 寿大伟 王平 《浙江医学》 CAS 2018年第14期1544-1547,1552,共5页
目的探讨血清甲状腺球蛋白(TG)水平对甲状腺未全部切除(未全切)的分化型甲状腺癌(DTC)患者术后是否发生肿瘤残留或复发/转移的诊断价值。方法将甲状腺未全切术后发生肿瘤残留或复发/转移的93例DTC患者作为研究组(A组),未发生肿瘤残留或... 目的探讨血清甲状腺球蛋白(TG)水平对甲状腺未全部切除(未全切)的分化型甲状腺癌(DTC)患者术后是否发生肿瘤残留或复发/转移的诊断价值。方法将甲状腺未全切术后发生肿瘤残留或复发/转移的93例DTC患者作为研究组(A组),未发生肿瘤残留或复发/转移的118例DTC患者作为对照组(B组);甲状腺球蛋白抗体(TGAB)阴性的65例A组患者设为C组,79例B组患者设为D组;TG阴性的46例A组患者设为E组,112例B组患者设为F组。分别比较A、B组间和A组二次手术前后以及C、D组间的TG水平差异,并分别比较A、B组间和A组二次手术前后以及E、F组间的TGAB水平差异;通过ROC曲线分别进行TG和TGAB的诊断价值评估。A、C、E各组均为二次手术前的水平,B、D、F各组均为术后随访水平。结果 A组、A组术前、C组的TG水平分别高于B组、A组术后、D组的TG水平(均P<0.05)。A、B组间和A组二次手术前后以及E、F组间的TGAB水平比较均无统计学差异(均P>0.05)。TG水平监测对未全切DTC发生术后肿瘤残留或复发/转移有诊断价值(AUC=0.758,P<0.05),灵敏度为0.505,特异度为0.949,提示无病生存的临界值为7.94IU/ml;而TGAB则无诊断价值。结论血清TG水平监测对于甲状腺未全切的DTC患者术后发生肿瘤残留或复发/转移具有一定的诊断价值,在随访中TG水平监测应列为常规检查项目。 展开更多
关键词 分化型甲状腺癌 甲状腺球蛋白 甲状腺球蛋白抗体
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CT引导下放射性粒子125I植入治疗骨转移瘤患者的临床研究 被引量:11
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作者 费伦 郭金友 +3 位作者 郑家平 梅伟东 韩瑞雪 沈剑英 《介入放射学杂志》 CSCD 北大核心 2020年第9期930-933,共4页
目的探讨125I粒子植入治疗骨转移瘤患者的有效性和安全性。方法将骨转移瘤患者54例分为两组,其中行125I粒子植入的30例患者为治疗组,植入粒子总数1581粒,平均每例植入(52±6)粒,另24例患者行药物治疗为对照组,比较两组的疼痛治疗有... 目的探讨125I粒子植入治疗骨转移瘤患者的有效性和安全性。方法将骨转移瘤患者54例分为两组,其中行125I粒子植入的30例患者为治疗组,植入粒子总数1581粒,平均每例植入(52±6)粒,另24例患者行药物治疗为对照组,比较两组的疼痛治疗有效率(NRS评分)、功能状态改善有效率(KPS评分)、以及病灶治疗疗效的差异,比较两组治疗前后的血清碱性磷酸酶(ALP)变化,不良反应和并发症的发生情况。结果治疗组的功能状态改善率为60%,高于对照组的29.2%;治疗组的镇痛显效率为36.2%,高于对照组的4.2%;病灶治疗的临床有效率为93.3%,高于对照组的8.3%,差异均有统计学意义(均P<0.05)。治疗组治疗后血清ALP水平降低,差异有统计学意义(P<0.05)。无严重不良反应和125I粒子植入能有效缓解骨转移瘤引起的疼痛,提高生活质量,是一种安全、有效的治疗方法。 展开更多
关键词 125I放射性粒子 骨转移瘤 癌痛 KPS NRS
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1961—2019年阿富汗土地资源承载力变化研究——基于膳食营养当量视角
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作者 查思含 马玮哲 +5 位作者 王思嘉 张丹 胡起源 高翔 伦飞 何露 《世界地理研究》 CSSCI 北大核心 2024年第2期53-63,共11页
为了我国周边安全和“一带一路”倡议的顺利推进,应充分认识阿富汗地区的粮食安全问题及土地承载力演变情况。本研究从膳食营养需求的角度出发,通过构建土地资源承载力评价模型,研究了近六十年来阿富汗地区土地资源承载力变化情况,并根... 为了我国周边安全和“一带一路”倡议的顺利推进,应充分认识阿富汗地区的粮食安全问题及土地承载力演变情况。本研究从膳食营养需求的角度出发,通过构建土地资源承载力评价模型,研究了近六十年来阿富汗地区土地资源承载力变化情况,并根据未来不同情景,探讨了阿富汗地区土地资源承载力的优化路径。结果表明:随着膳食营养需求和人口的增加,阿富汗地区土地资源已无法满足本国居民的消费需求,土地资源承载压力逐渐增加,已经由基本平衡阶段(1961—1978)和态势趋紧阶段(1979—1998),演变为人地矛盾突出阶段(1999—2019)。从三种膳食营养当量(热量、蛋白质和脂肪)来看,阿富汗地区土地资源均处于超载状态,其中基于脂肪需求的土地资源承载压力最大。为了满足当地食物消费需求增长和土地资源的可持续发展,阿富汗当局一方面应大力推行“毒改粮”政策并提高土地生产力,另一方面也应当积极引导合适健康饮食。此外,本文还探讨了影响阿富汗土地资源承载力的主要因素,以期为进一步缓解与改善阿富汗地区粮食安全问题及其人地关系提供参考。 展开更多
关键词 土地资源承载力 阿富汗 膳食营养 粮食安全 情景分析
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Water consumption and biodiversity:Responses to global emergency events
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作者 Dandan Zhao Junguo Liu +15 位作者 Laixiang Sun Klaus Hubacek Stephan Pfister Kuishuang Feng Heran Zheng Xu Peng Daoping Wang Hong Yang Lei Shen fei lun Xu Zhao Bin Chen Marko Keskinen Shaohui Zhang Jialiang Cai Olli Varis 《Science Bulletin》 SCIE EI CAS CSCD 2024年第16期2632-2646,共15页
Given that it was a once-in-a-century emergency event,the confinement measures related to the coronavirus disease 2019(COVID-19)pandemic caused diverse disruptions and changes in life and work patterns.These changes s... Given that it was a once-in-a-century emergency event,the confinement measures related to the coronavirus disease 2019(COVID-19)pandemic caused diverse disruptions and changes in life and work patterns.These changes significantly affected water consumption both during and after the pandemic,with direct and indirect consequences on biodiversity.However,there has been a lack of holistic evaluation of these responses.Here,we propose a novel framework to study the impacts of this unique global emergency event by embedding an environmentally extended supply-constrained global multi-regional input-output model(MRIO)into the drivers-pressure-state-impact-response(DPSIR)framework.This framework allowed us to develop scenarios related to COVID-19 confinement measures to quantify country-sector-specific changes in freshwater consumption and the associated changes in biodiversity for the period of 2020-2025.The results suggest progressively diminishing impacts due to the implementation of COVID-19 vaccines and the socio-economic system’s self-adjustment to the new normal.In 2020,the confinement measures were estimated to decrease global water consumption by about 5.7% on average across all scenarios when compared with the baseline level with no confinement measures.Further,such a decrease is estimated to lead to a reduction of around 5% in the related pressure on biodiversity.Given the interdependencies and interactions across global supply chains,even those countries and sectors that were not directly affected by the COVID-19 shocks experienced significant impacts:Our results indicate that the supply chain propagations contributed to 79% of the total estimated decrease in water consumption and 84%of the reduction in biodiversity loss on average.Our study demonstrates that the MRIO-enhanced DSPIR framework can help quantify resource pressures and the resultant environmental impacts across supply chains when facing a global emergency event.Further,we recommend the development of more locally based water conservation measures—to mitigate the effects of trade disruptions—and the explicit inclusion of water resources in post-pandemic recovery schemes.In addition,innovations that help conserve natural resources are essential for maintaining environmental gains in the post-pandemic world. 展开更多
关键词 Global emergency events Water-biodiversity causal effect COVID-19 BIODIVERSITY MRIO-enhanced DPSIR framework Supply-chain network High-resolution water consumption dataset Supply-constrained multi-regional input-output(mixed MRIO)model
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基于变权重变异鸽群优化的无人机空中加油自抗扰控制器设计 被引量:13
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作者 费伦 段海滨 +2 位作者 徐小斌 鲍瑞 孙永斌 《航空学报》 EI CAS CSCD 北大核心 2020年第1期256-265,共10页
针对空中加油过程中的受油机模型建模误差和强扰动以及自抗扰控制器(ADRC)人工参数整定难的问题,提出了一种基于变权重变异鸽群优化(VWMPIO)算法的无人机自抗扰控制器优化算法。首先,给出了六自由度无人机(UAV)模型,基于自抗扰控制结构... 针对空中加油过程中的受油机模型建模误差和强扰动以及自抗扰控制器(ADRC)人工参数整定难的问题,提出了一种基于变权重变异鸽群优化(VWMPIO)算法的无人机自抗扰控制器优化算法。首先,给出了六自由度无人机(UAV)模型,基于自抗扰控制结构设计了一种受油机的姿态控制器,在此基础上用所提出的变权重变异鸽群优化算法整定了自抗扰控制器参数。随后,将变权重变异鸽群优化与其他基本鸽群优化算法、粒子群优化算法进行了实验对比,并从控制性能和抗噪声性能的角度对自抗扰控制器和传统的比例-微分-积分(PID)控制器进行了仿真对比。实验结果表明所提算法能提高复杂态势环境下无人机空中加油的控制精度和扰动抑制性能。 展开更多
关键词 空中加油 变权重变异鸽群优化算法 自抗扰控制 参数整定 姿态控制
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Spectral characteristic of infrared radiations of some acupoint and non-acupoint areas in human arm surface 被引量:9
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作者 DING Guanghong YAO Wei +8 位作者 CHU Junhao SHEN Xueyong HUANG Zhiming CHENG Huansheng LIU Hui WANG Shenzhang YANG Jing WEI Hu fei lun 《Chinese Science Bulletin》 SCIE EI CAS 2001年第8期678-682,共5页
Using infrared spectrum detective device, we experiment on Neiguan, Laogong and Hegu acupoints of seven adult volunteers as well as contrastive points beside ones. We get 63 infrared spectrums. The experiment outcome ... Using infrared spectrum detective device, we experiment on Neiguan, Laogong and Hegu acupoints of seven adult volunteers as well as contrastive points beside ones. We get 63 infrared spectrums. The experiment outcome tells us that the differences of the intensities among individuals are great, and so are the differences between acupoint and non-acupoint areas. However, the differences of spectral character are small, which indicates that infrared radiations of human body are based on the same biophysical fundament. 展开更多
关键词 ACUPOINT INFRARED RADIATION SPECTRUM energy channel.
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A FLUID MECHANICS MODEL OF TISSUE FLUID FLOW IN LIMB CONNECTIVE TISSUE——A MECHANISM OF ACUPUNCTURE SIGNAL TRANSMISSION 被引量:4
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作者 ZHANG Di YAO Wei +6 位作者 DING Guang-hong YANG Jing SCHWARZ Wolfgang fei lun LIU Fang SHEN Xue-yong LAO Li-xing 《Journal of Hydrodynamics》 SCIE EI CSCD 2009年第5期675-684,共10页
This article explores the mechanisms of acupuncture meridians by determining characteristics of the tissue fluid flow in the connective tissue along meridians. Based on deep dissection of acupoints on the upper and lo... This article explores the mechanisms of acupuncture meridians by determining characteristics of the tissue fluid flow in the connective tissue along meridians. Based on deep dissection of acupoints on the upper and lower limbs of the human body and micro and macro observation and measurement, a mathematical model of the flow of tissue fluid in interosseous membranes is constructed. It is shown that the signal transmission along acupuncture meridians may be determined by unique anatomical and physiological factors that govern the flow of tissue fluid in the connective tissue and involve mast cell degranulation. Our results provide a preliminary explanation of the phenomenon of the "de qi" sensation and the mechanism of acupuncture signal transmission along acupuncture meridians. 展开更多
关键词 ACUPUNCTURE MERIDIAN tissue-fluid flow mast cell
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Evaluation of Climatic Comfort of Living Environment based on Age Differentials in Beijing-Tianjin-Hebei Area 被引量:1
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作者 Siyu Liu Buju Long +6 位作者 Zhihua Pan fei lun Yu Song Weiying Yuan Na Huang Ziyuan Zhang Shangqian Ma 《Ecosystem Health and Sustainability》 SCIE 2020年第1期252-263,251,共13页
Somatosensory comfort is mainly determined by the Temperature and Humidity Index(THI)with Wind Efficiency Index(WEI),but this conventional usage of these indicators does not capture the age-related differentials.Here ... Somatosensory comfort is mainly determined by the Temperature and Humidity Index(THI)with Wind Efficiency Index(WEI),but this conventional usage of these indicators does not capture the age-related differentials.Here we resolved this gap with a modification of the climatic comfort definition and method in a national standard,denoted as the Relative Climate Sensitive Index(RCSI),which incorporated the age-related vulnerability scores determined through online questionnaires with a scoring method,for each of the age-related and adaptive climatic comfort responses to changes in residence with Beijing-Tianjin-Hebei(BTH)region as an example.First,the result showed that the human comfort of living environment decreased with age in the BTH region,implicating age obviously impacted comfort,and weak adaptability made the elderly the relatively most high-risk group-their suitable region was less than a quarter of the whole study region.Second the adverse effects of persistent hot weather on comfort,indicating global warming as the leading driver of dwindling comfort over recent years.As the warming was more significant in the southeastern part,all these forces combined had there a hotspot,appealing for extra attention.Last this improved evaluation accorded with actual situation to captured high-risk groups with their distributions. 展开更多
关键词 Global climate change climatic comfort vulnerable population the Beijing-Tianjin-Hebei Region
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