Surface blood compatibility of ion beam and plasma treatment on polyetherurethane has been studied.O^(+)implantation was performed at 80keV with various doses.O_(2) plasma treatment was carried out at 100 W with vario...Surface blood compatibility of ion beam and plasma treatment on polyetherurethane has been studied.O^(+)implantation was performed at 80keV with various doses.O_(2) plasma treatment was carried out at 100 W with various exposure times.The results indicated that surface anticogulability was enhanced in varying degrees and anticalcific behavior was not decreased.X-ray photoelectron spectroscopy and electron spin resonance analysis showed that the two methods not only broke some chemical bonds,but also produced some new N-O and C-O bonds and radicals in the surface,which affected the surface biomedical behavior.展开更多
Chitin is a kind of seemly material to match PLLA for a scaffold, which may create an appropriate environment for the regeneration of tissues. In this study, we evaluated hydrophilicity of a new nano-hydroxyapatite/co...Chitin is a kind of seemly material to match PLLA for a scaffold, which may create an appropriate environment for the regeneration of tissues. In this study, we evaluated hydrophilicity of a new nano-hydroxyapatite/collagen/PLLA (nHACP) scaffold optimized by chitin fibres for bone tissue engineering. The results show that with the CF content increase, hydrophilicity of nHACP/CF increases, which reflects from the side that the addition of the chitin fibres can improve the cytocompatibility of the nHACP. Moreover, crosslink does not take significant influences on the material hydrophilicity. The results suggest that nHACP/CF with the crosslink should be a kind of potential appropriate scaffold for tissue engineering.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No.19305006the Natural Science Foundation of Tianjinby the Ion Beam Laboratory,Shanghai Institute of Metallurgy,Chinese Academy of Sciences.
文摘Surface blood compatibility of ion beam and plasma treatment on polyetherurethane has been studied.O^(+)implantation was performed at 80keV with various doses.O_(2) plasma treatment was carried out at 100 W with various exposure times.The results indicated that surface anticogulability was enhanced in varying degrees and anticalcific behavior was not decreased.X-ray photoelectron spectroscopy and electron spin resonance analysis showed that the two methods not only broke some chemical bonds,but also produced some new N-O and C-O bonds and radicals in the surface,which affected the surface biomedical behavior.
基金National Natural Science Foundation of Chinagrant number:31000431 and 10925208+1 种基金Bejing Nove Programgrant number:2010B011
文摘Chitin is a kind of seemly material to match PLLA for a scaffold, which may create an appropriate environment for the regeneration of tissues. In this study, we evaluated hydrophilicity of a new nano-hydroxyapatite/collagen/PLLA (nHACP) scaffold optimized by chitin fibres for bone tissue engineering. The results show that with the CF content increase, hydrophilicity of nHACP/CF increases, which reflects from the side that the addition of the chitin fibres can improve the cytocompatibility of the nHACP. Moreover, crosslink does not take significant influences on the material hydrophilicity. The results suggest that nHACP/CF with the crosslink should be a kind of potential appropriate scaffold for tissue engineering.
