Dear Editor,Appendectomy is usually performed to treat acute appendicitis although it may also be conducted in the absence of appendicitis when patients suffer from chronic abdominal pain.Resection is also known to mi...Dear Editor,Appendectomy is usually performed to treat acute appendicitis although it may also be conducted in the absence of appendicitis when patients suffer from chronic abdominal pain.Resection is also known to mitigate the risk of ulcerative colitis[1],a risk factor for colorectal cancer.The impact of appendectomy on colorectal cancer risk,particularly in the long term,is unclear.The procedurewas initially hypothesized to increase colorectal cancer risk due to decreased immunocompetency.展开更多
基金The French E3N cohort is maintained with the support of the Mutuelle Générale de l’Education Nationale(MGEN),Gustave Roussy and the French League against Cancer(LNCC).E3N-E4N is also supported by the French National Research Agency(ANR)under the Investment for the future Program(PIA)(ANR-10-COHO-0006)by the French Ministry of Higher Education,Research and Innovation(subsidy#2102918823).
文摘Dear Editor,Appendectomy is usually performed to treat acute appendicitis although it may also be conducted in the absence of appendicitis when patients suffer from chronic abdominal pain.Resection is also known to mitigate the risk of ulcerative colitis[1],a risk factor for colorectal cancer.The impact of appendectomy on colorectal cancer risk,particularly in the long term,is unclear.The procedurewas initially hypothesized to increase colorectal cancer risk due to decreased immunocompetency.