Objectives: This study investigates the prevalence of obesity in children with familial Mediterranean fever (FMF). Material and Methods: We retrospectively reviewed the medical records of 70 patients with FMF whose ca...Objectives: This study investigates the prevalence of obesity in children with familial Mediterranean fever (FMF). Material and Methods: We retrospectively reviewed the medical records of 70 patients with FMF whose cases had been followed in our Pediatric Nephrology and Rheumatology Unit. The height and weight measurements of children with FMF were obtained and body mass index was calculated. Results: The mean body mass index was 16.7± 2.4 in the boys, and 17.4±2.9 in the girls. Nine of the children (five boys, four girls) were found to be overweight, a rate of 12.8% in FMF patients. Obesity was not detected in FMF patients. Conclusions: We think that there are some unligteening molecular mechanisms that prevent obesity in FMF patients. Due to the limited number of patients in this study, further research involving more patients are needed.展开更多
The present study aimed to investigate the correlation of MPV and splenomegaly as inflammation activity of FMF patients at the attacks free period. We retrospectively reviewed the medical records of 43 patients with F...The present study aimed to investigate the correlation of MPV and splenomegaly as inflammation activity of FMF patients at the attacks free period. We retrospectively reviewed the medical records of 43 patients with FMF. This study was performed at the attack free period as clinical and laboratory. For this study, patients were divided into two groups. Patients with splenomegaly is called group 1 (n = 12) and patients with no splenomegaly is called group 2 (n = 31). Groups were compared respect to age, gender, platelet counts, acute phase reactants and MPV. The mean MPV (fl) were significantly higher in group 1 (8.9 ±0.8) than in group 2 (8.4 ±0.5, p 【0.05). This study suggested that increased MPV and splenomegaly without amyloidosis could be a sign of chronic inflammation in children with FMF even in attack free period.展开更多
文摘Objectives: This study investigates the prevalence of obesity in children with familial Mediterranean fever (FMF). Material and Methods: We retrospectively reviewed the medical records of 70 patients with FMF whose cases had been followed in our Pediatric Nephrology and Rheumatology Unit. The height and weight measurements of children with FMF were obtained and body mass index was calculated. Results: The mean body mass index was 16.7± 2.4 in the boys, and 17.4±2.9 in the girls. Nine of the children (five boys, four girls) were found to be overweight, a rate of 12.8% in FMF patients. Obesity was not detected in FMF patients. Conclusions: We think that there are some unligteening molecular mechanisms that prevent obesity in FMF patients. Due to the limited number of patients in this study, further research involving more patients are needed.
文摘The present study aimed to investigate the correlation of MPV and splenomegaly as inflammation activity of FMF patients at the attacks free period. We retrospectively reviewed the medical records of 43 patients with FMF. This study was performed at the attack free period as clinical and laboratory. For this study, patients were divided into two groups. Patients with splenomegaly is called group 1 (n = 12) and patients with no splenomegaly is called group 2 (n = 31). Groups were compared respect to age, gender, platelet counts, acute phase reactants and MPV. The mean MPV (fl) were significantly higher in group 1 (8.9 ±0.8) than in group 2 (8.4 ±0.5, p 【0.05). This study suggested that increased MPV and splenomegaly without amyloidosis could be a sign of chronic inflammation in children with FMF even in attack free period.
