BACKGROUND Carbapenem-resistant Enterobacteriaceae has become a significant public health concern as hospital outbreaks are now being frequently reported and these organisms are becoming difficult to treat with the av...BACKGROUND Carbapenem-resistant Enterobacteriaceae has become a significant public health concern as hospital outbreaks are now being frequently reported and these organisms are becoming difficult to treat with the available antibiotics.CASE SUMMARY An outbreak of VIM-producing Serratia marcescens occurred over a period of 11 wk(August,1 to October,18)in patients admitted to the adult polyvalent intensive care unit of the University of Campania“Luigi Vanvitelli”located in Naples.Four episodes occurred in three patients(two patients infected,and one patient colonized).All the strains revealed the production of VIM.CONCLUSION After three decades of carbapenem antibiotics use,the emergence of carbapenemresistance in Enterobacteriaceae has become a significant concern and a stricter control to preserve its clinical application is mandatory.This is,to our knowledge,the first outbreak of VIM-producing Serratia marcescens in Europe.Surveillance policies must be implemented to avoid future outbreaks.展开更多
文摘BACKGROUND Carbapenem-resistant Enterobacteriaceae has become a significant public health concern as hospital outbreaks are now being frequently reported and these organisms are becoming difficult to treat with the available antibiotics.CASE SUMMARY An outbreak of VIM-producing Serratia marcescens occurred over a period of 11 wk(August,1 to October,18)in patients admitted to the adult polyvalent intensive care unit of the University of Campania“Luigi Vanvitelli”located in Naples.Four episodes occurred in three patients(two patients infected,and one patient colonized).All the strains revealed the production of VIM.CONCLUSION After three decades of carbapenem antibiotics use,the emergence of carbapenemresistance in Enterobacteriaceae has become a significant concern and a stricter control to preserve its clinical application is mandatory.This is,to our knowledge,the first outbreak of VIM-producing Serratia marcescens in Europe.Surveillance policies must be implemented to avoid future outbreaks.
