There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health....There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health.As a result,the hazards and risks of nanoplastics remain uncertain.Here,we identify key knowledge gaps by evaluating the exposure of nanoplastics in the environment,assessing their bio-nano interactions,and examining their potential risks to humans and the environment.We suggest considering nanoplastics a complex and dynamic mixture of polymers,additives,and contaminants,with interconnected risks to environmental and human health.We call for comprehensive integration of One Health approach to produce robust multidisciplinary evidence to nanoplastics threats at the planetary level.Although there are many challenges,this holistic approach incorporates the relevance of environmental exposure and multi-sectoral responses,which provide the opportunity to identify the risk mitigation strategies of nanoplastics to build resilient health systems.展开更多
基金supported by the Youth Innovation Promotion Association,Chinese Academy of Sciences(2020314)the National Natural Science Foundation of China(41977355)+1 种基金China Postdoctoral Science Foundation(2021M703303)the USDA Hatch program(MAS 00549).
文摘There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health.As a result,the hazards and risks of nanoplastics remain uncertain.Here,we identify key knowledge gaps by evaluating the exposure of nanoplastics in the environment,assessing their bio-nano interactions,and examining their potential risks to humans and the environment.We suggest considering nanoplastics a complex and dynamic mixture of polymers,additives,and contaminants,with interconnected risks to environmental and human health.We call for comprehensive integration of One Health approach to produce robust multidisciplinary evidence to nanoplastics threats at the planetary level.Although there are many challenges,this holistic approach incorporates the relevance of environmental exposure and multi-sectoral responses,which provide the opportunity to identify the risk mitigation strategies of nanoplastics to build resilient health systems.