Asherman’s syndrome(AS)is an endometrial disorder in which intrauterine adhesions crowd the uterine cavity and wall.The fibrotic adhesions are primarily the result of invasive uterine procedures that usually involve ...Asherman’s syndrome(AS)is an endometrial disorder in which intrauterine adhesions crowd the uterine cavity and wall.The fibrotic adhesions are primarily the result of invasive uterine procedures that usually involve the insertion of surgical equipment into the uterus.This syndrome is accompanied by a number of clinical manifestations,including irregular or painful menstruation and infertility.The most prevalent treatment is hysteroscopy,which involves the physical removal of the fibrous strands.Within the last decade,however,the field has been exploring the use of cellbased therapeutics,in conjunction with biomaterials,to treat AS.This review is a recapitulation of the literature focused on cellular therapies for treating AS.展开更多
基金the National Institutes of Health(R01HL123920 and R01HL137093 to K.C.).Final grammatical edits were made by Jhon Cores,PhD.
文摘Asherman’s syndrome(AS)is an endometrial disorder in which intrauterine adhesions crowd the uterine cavity and wall.The fibrotic adhesions are primarily the result of invasive uterine procedures that usually involve the insertion of surgical equipment into the uterus.This syndrome is accompanied by a number of clinical manifestations,including irregular or painful menstruation and infertility.The most prevalent treatment is hysteroscopy,which involves the physical removal of the fibrous strands.Within the last decade,however,the field has been exploring the use of cellbased therapeutics,in conjunction with biomaterials,to treat AS.This review is a recapitulation of the literature focused on cellular therapies for treating AS.
