THE SHOCK WAVES FOR A MIXED-TYPE SYSTEM FROM CHEMOTAXIS

In this paper,we study the shock waves for a mixed-type system from chemotaxis.We are concerned with the jump conditions for the left state which is located in the elliptical region and the right state in the hyperbolic region.Under the generalized entropy conditions,we find that there are different shock wave structures for different parameters.To guarantee the uniqueness of the solutions,we obtain the admissible shock waves which satisfy the generalized entropy condition in both parameters.Finally,we construct the Riemann solutions in some solvable regions.

糖尿病视网膜病变患者血清CMKLR1水平及临床意义

目的:探讨糖尿病视网膜病变(DR)患者血清CMKLR1水平及临床意义。方法:选取2015-02/2018-03在我院治疗的2型糖尿病(T2DM)患者140例,其中单纯T2DM患者45例,DR患者95例(NPDR患者54例,PDR患者41例),并纳入健康志愿者40例。收集临床资料并检测血清CMKLR1水平。结果:PDR患者糖尿病病程长于NPDR和NDR患者,且NPDR患者长于NDR患者(均P<0.05)。T2DM患者FPG和血清TG水平升高,HDL-C水平降低,且DR患者LDL-C水平高于NDR患者和健康志愿者(均P<0.05)。PDR患者血清CMKLR1水平高于NPDR、T2DM患者和健康志愿者,且NPDR患者高于NDR患者和健康志愿者,NDR患者高于健康志愿者(均P<0.05)。DR患者血清CMKLR1水平与糖尿病病程、HbA1c和LDL-C呈正相关(r=0.374、0.248、0.304,均P<0.05),其中糖尿病病程和血清CMKLR1水平是DR发生的危险因素(OR=1.594、1.830,均P<0.05)。结论:DR患者血清中CMKLR1水平升高,且与病情进展有关,是影响DR发生发展的重要危险因素。

A mutated CRYGD associated with congenital coralliform cataracts in two Chinese pedigrees

AIM:To investigate the causal gene mutation and clinical characteristics for two Chinese families with autosomal dominant congenital coralliform cataract.METHODS:Two Chinese pedigrees with congenital cataract were investigated.Routine ophthalmic examinations were performed on all patients and non-affected family members.Peripheral blood samples were collected,and the genomic DNAs were extracted.The coding regions of proband’s DNAs were analyzed with cataract gene panel.The identified mutation was amplified by polymerase chain reaction,and automated sequencing was performed in other members of two families to verify whether the mutated gene was co-segregated with the disease.RESULTS:Congenital coralliform cataract was inherited in an autosomal dominant mode in both pedigrees.For each family,more than half of the family members were affected.All patients presented with severe visual impairment after birth as a result of bilateral symmetric coralliform lens opacification.An exact the same defect in the same gene,a heterozygous mutation of c.70 C>A(p.P24 T)in exon 2 of γ Dcrystallin gene,was detected in both probands from each family.Sanger sequencing analysis demonstrated that the mutated CRYGD was co-segregated in these two families.CONCLUSION:A c.70 C>A(p.P24 T)variant in CRYGD gene was reconfirmed to be the causal gene in two Chinese pedigrees.It is known that mutated CRYGD caused most of the congenital coralliform cataracts,suggesting that the CRYGD gene is associated with coralliform congenital cataract.

Investigation of a root zone heating system for greenhouse seedling and its effects on micro-environment

Under the extremely cold climatic condition,crops have to survive severe heat stress conditions,even if they are being kept in greenhouses.In the winter and spring of North China,the air and soil temperature is low inside the greenhouse,and when using a traditional heating system,the energy consumption is high.This paper reports on a study of different design solutions for a root zone heating system based on a kind of low temperature radiation material.Root zone heating systems offer increasing crop quality and productivity.A novel type of heat preservation and root zone heating system was applied in greenhouse seedling.And through multiple experiments,the effect of the root zone heating system on the ambient environment and seedbed surface was studied,and the heat preservation effect and heating uniformity were discussed.Results show that single-layer film covering on the root zone heating system can make the average temperature at night increase 1°C.And the average seedbed surface and substrate temperature can increase 11.3°C and 5.2°C,respectively.In conclusion,the root zone heating system can effectively improve the environmental temperature of seedling and the uniformity of heating is high,which provides a strong guarantee for high-quality seedling cultivation.

Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias

In early life, the immune system plays an essential role in brain development. In our study, the immunopotentiator thymosin alpha-1（Ta1） was peripherally administered to neonatal mice to explore whether the peripheral immunopotentiator affects neurodevelopment and cognition, and to further investigate the relevant mechanism. Compared with the control group, the Ta1 mice displayed better cognitive abilities in early life. The numbers of 5-bromodeoxyuridine（Brd U）＋, nestin＋,T-box transcription factor 2（Tbr2）＋, Brd U＋/doublecortin（DCX）＋, Brd U＋/ionized calcium-binding adaptor molecule 1（Iba1）＋, and Brd U＋/neuronal nuclei（Neu N）＋ cells in the hippocampus were increased in the Ta1 group,accompanied by increased interleukin-4（IL-4）, interferon-gamma, brain-derived neurotrophic factor, nerve growth factor, and insulin-like growth factor-1 as well as decreased IL-6 and tumor necrosis factor-a. Furthermore, the Ta1-group showed a Th1-polarized immune response, and the neurotrophic factors were positively associated with the Th1/Th2 ratio. More importantly, administration of Ta1 blocked lipopolysaccharide-induced impairment of hippocampal neurogenesis in early life. These findings suggest that peripheral Ta1 contributes to neurogenesis and cognition probably through a systemic Th1 bias, as well as neuroprotection against LPS infection by Ta1.

Effects of different root zone heating systems on the microclimate and crop development in solar greenhouses

Heating greenhouse is indispensable for plant development particularly in winter when the air temperature is lower.In that sense,root zone heating is more energy-saving than traditional air heating.The current work was devoted to the study of the effect of two root zone heating systems based on carbon crystal electrothermal film and low temperature hot water pipe on the microclimate and tomato yield in solar greenhouse.And their performance was tested in the coldest period of winter in Yongqing County of Hebei Province.The results showed that the use of root zone heating system can improve the average substrate temperature by 6.8℃.This microclimate improvement had a positive impact on tomato production.The output per square meter has increased by 19%compared to the unheated.It was also noted that the presence of root zone heating leads to a decrease in the development of disease in heated areas.Based on these results,the root zone heating system can be an effective method of improving the environmental temperature of crop plant,which is of great significance for increasing crop yield.

Optimization of Chinese solar greenhouse building parameters based on CFD simulation and entropy weight method

The building parameters of Chinese solar greenhouse(CSG)directly affect the front roof lighting and indoor thermal environment.In order to obtain the optimal parameter combination,a building parameter optimization method based on computational fluid dynamics(CFD)simulation and entropy weight method was proposed.Firstly,a three-dimensional thermal and humidity environment model of CSG was constructed considering the coupling effect of soil,crop,and back wall based on CFD.The reliability of the model was validated through experiments in a CSG of Yongqing County,Hebei Province of China.Then,the indoor air temperature rise rate,air temperature and humidity uneven coefficient,and average air temperature and humidity were selected as the evaluation indicators of CSG thermal and humidity environment.The ridge height,back wall height and the horizontal projection of back roof of CSG were selected as the three factors of the orthogonal test plan,and a three-factor and four-level plan was designed,resulting in 16 different parameter combinations.By use of CFD simulation,the thermal and humidity environment evaluation indicators under different parameter combinations were calculated.The entropy weight method was used to assign weights to the evaluation indicators,and the comprehensive evaluation indicators of CSG thermal and humidity environment were obtained based on the linear weighting principle.By comparing comprehensive evaluation indicators,the optimal combination of building parameters was obtained with a ridge height of 5.72 m,a back wall height of 3.2 m,and a horizontal projection of 2.1 m on the back roof.The research results can provide a practical and feasible method for optimizing the building parameters of CSG,and provided theoretical guidance for the structural design and optimization of CSG.

运动视觉及视觉训练的研究进展

运动视觉也称运动视力,是人在运动过程中通过观察环境和事物的变化后,对自己的动作及时做出反馈调整的能力.运动视觉是视觉领域的一个新学科,主要包括评价和提高视觉表现力,对视觉问题进行诊断,并提供必要的视觉训练帮助.视觉训练是一种眼睛和大脑的训练方式,是对大脑视觉神经认知系统的刺激与训练.目前该研究在很多体育运动项目中受到广泛关注,已成为一个新兴热点.运动员的运动视觉能力基本上是在长期的训练和比赛实践中得到增长的,现就其国内外的研究成果作一综述.

Effect of salinity on community structure and naphthalene dioxygenase gene diversity of a halophilic bacterial consortium

The aim of this study is to analyze the effect of salinity on polycyclic aromatic hydrocarbons （PAHs） biodegradation, community structure and naphthalene dioxygenase gene （ndo） diversity of a halophilic bacterial consortium with the denaturing gradient gel electrophoresis （DGGE） approach. The consortium was developed from oil-contaminated saline soil after enrichment for six times, using phenanthrene as the substrate. The prominent species in the bacterial consortium at all salinities were identified as halophilic bacteria Halomonas, Alcanivorax, Marinobacter, Idiomarina, Martelella and uncultured bacteria. The predominant microbes gradually changed associating with the saline concentration fluctuations ranging from 0.1% to 25% （w/v）. Two ndo alpha subunits were dominant at salinities ranging, from 0.1% to 20%. while not been clearly detected at 25% salinity. Consistently. the biodegradation occurred at salmltles rangmg from 0.1% to 20%, while no at 25% salinity, suggesting the two ndo genes played an important role in the degradation. The phylogenetic analysis revealed that both of the two ndo alpha subunits were related to the classic nab-like gene from Pseudomonas stutzeri AN10 and Pseudomonas aeruginosa PaK1, while one with identity of about 82% and the other one with identity of 90% at amino acid sequence level. We concluded that salinity greatly affected halophilic bacterial community structure and also the functional genes which were more related to biodegradation.

Analysis of moisture and total sugar content of Huizao based on surface images

Moisture and total sugar content are two important internal qualities of Huizao.In order to explore their correlation with external qualities,a novel method of moisture and total sugar content analysis was proposed based on surface images.Firstly,five geometric features and seven texture features of Huizao were obtained to be the external quality indexes by digital image processing technology.Secondly,the wrinkle degree as an important index was extracted by marked watershed segmentation algorithm.According to the external quality the Huizao samples were grouped,and the moisture and total sugar content were determined through physical and chemical methods.Lastly,the moisture and total sugar content and twelve external indexes were all processed by step discriminatory analysis.Meanwhile,the regression models of moisture content with short diameter,contrast,and wrinkle degree and total sugar with wrinkle degree were established.The coefficients of the model were 0.9992 and 0.9978 respectively,and all the significance was less than 0.01,which show that the regression equation and regression coefficient effect are highly significant.The results indicate that the moisture and total sugar content of Huizao are greatly correlated with the wrinkle degree.The moisture and total sugar content are the highest when the wrinkle degree is at 2 to 3 grade,and they decrease gradually with the wrinkle degree increasing.Moisture content shows positive correlation with the size of Huizao.The results of model analysis agree well with the experimental results,which can provide valuable reference for improving Huizao grade diversity.

Study for entrained-flow gasifier modeling and measurement

The syngas composition change during the measurement process was analyzed using a detailed gas phase reaction mechanism.Results showed that the measurement error induced by the temperature and pressure change in the measurement process cannot be ignored.Based on the results,suggestions were proposed for syngas concentration measurement and temperature measurement.