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相位对比磁共振成像定量评估烟雾病患者血管重建术前后血流动力学 被引量:11
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作者 段宇 徐斌 +4 位作者 毛仁玲 高丰 冯江 陈功 李键 《国际脑血管病杂志》 2020年第3期185-190,共6页
目的采用相位对比磁共振成像(phase-contrast magnetic resonance imaging,PC-MRI)评估烟雾病患者脑血管重建术术前及术后6个月时的血流动力学,分析术后发生脑过度灌注综合征(cerebral hyperperfusion syndrome,CHS)的危险因素。方法回... 目的采用相位对比磁共振成像(phase-contrast magnetic resonance imaging,PC-MRI)评估烟雾病患者脑血管重建术术前及术后6个月时的血流动力学,分析术后发生脑过度灌注综合征(cerebral hyperperfusion syndrome,CHS)的危险因素。方法回顾性纳入2017年1月至2019年4月在复旦大学附属华东医院接受联合血管重建术的烟雾病患者。在术前及术后6个月行PC-MRI检查,记录颈内动脉、颈外动脉、颞浅动脉和椎动脉的血流速度、血流量以及血管管腔感兴趣区(regions of interest,ROI)面积。应用多变量logistic回归分析确定CHS的独立相关因素。结果共纳入80例烟雾病患者,男性35例(43.75%),年龄(42.4±10.1)岁(范围19~60岁)。术后6个月时颞浅动脉血流速度(P<0.05)、血流量(P<0.01)及ROI面积(P<0.01)均较术前显著增加,而椎动脉血流量变慢(P<0.05)。单变量分析显示,伴有糖尿病、优势半球侧手术、术前颞浅动脉血流速度加快、颈内动脉流量变小以及颈外动脉流量升高是烟雾病患者术后发生CHS的可能危险因素。多变量分析显示,优势半球侧手术[优势比(odds ratio,OR)4.627,95%可信区间(confidence internal,CI)1.019~21.009;P=0.047]、术前颞浅动脉血流量(OR 1.208,95%CI 1.053~1.387;P=0.007)和颈外动脉血流量(OR 0.139,95%CI 0.027~0.719;P=0.019)与术后CHS独立相关。结论PC-MRI能评估颅内外主要血管血流动力学参数,并可作为评价烟雾病术后风险的重要依据之一。 展开更多
关键词 烟雾病 脑血管重建术 手术后并发症 磁共振成像 脑血管循环 危险因素
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Memory and behavior-related problems of patients with neurocognitive disorders and the attitudes of their caregivers 被引量:1
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作者 Qingyan Wang fen jiang +1 位作者 Sanmei Chen Siyuan Tang 《Family Medicine and Community Health》 2013年第4期23-30,共8页
Objective:The purpose of this study was to investigate the memory and behavior-related problems of patients with neurocognitive disorders and the attitudes of their caregivers so as to provide an effective basis for n... Objective:The purpose of this study was to investigate the memory and behavior-related problems of patients with neurocognitive disorders and the attitudes of their caregivers so as to provide an effective basis for nursing interventions against such problems.Methods:The subjects were selected from patients who were under treatment or short-term hospitalization between April 2011 and March 2012.One hundred fifty-three patients with neurocognitive disorders and their major caregivers were selected from 9 grade 3 Class A hospitals of Hunan Province.The Revised Memory and Behavior Problems Checklist(RMBPC)was used to measure the memory and behavior-related problems of patients with neurocognitive disorders and the influence on their caregivers.The occurrence of different memory and behavior-related prob-lems and the distress on their caregivers was compared.Results:The RMBPC investigation showed that among 153 patients and their caregivers,152(99.3%)had memory-related problems,137(89.5%)had depression,and 136 patients(88.9%)had destructive behaviors.The incidence of memory-related problems was higher than depression and destructive behaviors(P<0.01).Caregivers bore more distress when encountering destructive behaviors(1.95±1.13 points)than memory-related problems and depression(0.91±0.76 points and 0.89±0.85 points;P<0.01).Curve fitting was used to analyze the relationship between the number of memory and behavior-related problems and the distress on their caregivers.A curve correlation existed between the two factors(the recorded maximum value of the Cubic equation curve was 0.278,F=229.212,P<0.05).Conclusion:Among patients with neurocognitive disorders,memory-related problems had the highest incidence,while the caregivers bore the strongest distress when encountering destructive behaviors,thus interventions should be conducted in consideration of patient memory and behavior-related problems,and caregivers’attitude to further reduce caregiver burden. 展开更多
关键词 Neurocognitive disorders Memory Disorder CAREGIVER Attitude Revised Memory and Behavior Problems Checklist
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Effect of a Patient Education Intervention on Asthma Control and Patient-Doctor Relationship 被引量:2
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作者 Yu-Qin Zeng David H Au +5 位作者 Shan Cai Evan Carey fen jiang Yan Chen Zhi-Jun Liu Ping Chen 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第9期1110-1112,共3页
To the Editor:Asthma control is the focus of modern asthma management,while only 2% of Chinese patients are controlled.[1] A good patient-doctor relationship is one of the first steps in the successful management of... To the Editor:Asthma control is the focus of modern asthma management,while only 2% of Chinese patients are controlled.[1] A good patient-doctor relationship is one of the first steps in the successful management of asthma;patients can know more information about their condition and the processes of their health through talking thoroughly with doctors.Due to large numbers of outpatients,most physicians in China spend no more than 5 min with a patient in clinics,limiting the opportunity to give the appropriate treatment and discuss further knowledge about asthma with the patients. 展开更多
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